Naturally Occurring Structural Isomers in Serum IgA1 O-Glycosylation (2012)
Kazuo Takahashi, Archer D. Smith, IV, Knud Poulsen, Mogens Kilian, Bruce A. Julian, Jiri Mestecky, Jan Novak, Matthew B. Renfrow
J Proteome Res, 2012 vol.11(2):692-702
SNFG,
Text,
Oxford
taxonomy (1)
protein (1)
source (1)
structure (3)
composition (3)
disease (2)
reference (1)
site (6)
peptide (2)
- Homo sapiens (Human)
Taxonomy
- Blood Plasma (UBERON_0001969)
Source
- O-Linked / Core 0 / GalNAc
- O-Linked / Core 8 / Gal(a1-3)GalNAc
- O-Linked / Undefined core / Gal(?1-3)GalNAc+"+ NeuAc(?2-?)"
Reported structure
- HexNAc:1 (avg mass : 221.2103 )
- Hex:1 HexNAc:1 (avg mass : 383.3527 )
- Hex:1 HexNAc:1 NeuAc:1 (avg mass : 674.6106 )
Composition
- Immunoglobulin heavy constant alpha 1 / Homo sapiens
Reported glycosite
- HYTNPSQDVTVPCPVPSTPPTPSP (24aa)
- STPPTPSPSCCHPR (14aa)
Mass spectrometry observed peptide
-
- O-Linked / Core 0
(avg mass : 221.2103)
- Blood Plasma (UBERON_0001969)
- Immunoglobulin heavy constant alpha 1 / Homo sapiens
- HYTNPSQDVTVPCPVPSTPPTPSP (24aa)
- STPPTPSPSCCHPR (14aa)
-
- O-Linked / Core 8
(avg mass : 383.3527)
- Blood Plasma (UBERON_0001969)
- Immunoglobulin heavy constant alpha 1 / Homo sapiens
- HYTNPSQDVTVPCPVPSTPPTPSP (24aa)
- STPPTPSPSCCHPR (14aa)
-
- O-Linked / Undefined core
(avg mass : 674.6106)
- Blood Plasma (UBERON_0001969)
- Control/Healthy
- Immunoglobulin heavy constant alpha 1 / Homo sapiens
- HYTNPSQDVTVPCPVPSTPPTPSP (24aa)
Source
Disease
Reported glycosite
Mass spectrometry observed peptide
- O-Linked / Undefined core
(avg mass : 674.6106)
Source
Reported glycosite
Mass spectrometry observed peptide
- O-Linked / Core 8
(avg mass : 383.3527)
Source
Reported glycosite
Mass spectrometry observed peptide
- O-Linked / Core 0
(avg mass : 221.2103)
