HYTNPSQDVTVPCPVPSTPPTPSP (24aa)

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin heavy constant alpha 1 / Homo sapiens    P01876

Source

• Blood Plasma (UBERON_0001969)  

Reported structure

• O-Linked / Core 0 / GalNAc
• O-Linked / Core 8 / Gal(a1-3)GalNAc
• O-Linked / Undefined core / Gal(?1-3)GalNAc+"+ NeuAc(?2-?)"

Composition

• HexNAc:1 (avg mass : 221.2103 )
• Hex:1 HexNAc:1 (avg mass : 383.3527 )
• Hex:1 HexNAc:1 NeuAc:1 (avg mass : 674.6106 )

Disease

• Control/Healthy
• Multiple myeloma (DOID:9538)

Reference

• Naturally Occurring Structural Isomers in Serum IgA1 O-Glycosylation (2012 - Kazuo Takahashi, Archer D. Smith, IV, Knud Poulsen, Mogens Kilian, Bruce A. Julian, Jiri Mestecky, Jan Novak, Matthew B. Renfrow) / Status : Reviewed

Reported glycosite

• Immunoglobulin heavy constant alpha 1 / Homo sapiens
  •        Thr-106
  •        Thr-109
  •        Ser-111
  •        Ser-113

Mass spectrometry observed peptide

• HYTNPSQDVTVPCPVPSTPPTPSP (24aa)
  •    P01876    Ser-113     Immunoglobulin heavy constant alpha 1 / Homo sapiens
  •    P01876    Thr-106     Immunoglobulin heavy constant alpha 1 / Homo sapiens
  •    P01876    Thr-109     Immunoglobulin heavy constant alpha 1 / Homo sapiens
  •    P01876    Ser-111     Immunoglobulin heavy constant alpha 1 / Homo sapiens