Adenocarcinoma

Taxonomy

• Homo sapiens (Human)
• Mus musculus (House mouse)

Protein

• Estrogen receptor / Homo sapiens    P03372
• Mucin-1 / Homo sapiens    P15941
• Unspecified mucin / Homo sapiens    
• Epiglycanin / Mus musculus    D9N008

Source

• Colon (UBERON_0001155)   LS174T (CVCL_1384)  
• Mammary Gland (UBERON_0001911)   MCF-7 (CVCL_0031)  
• Mammary Gland (UBERON_0001911)   TA3/Ha (CVCL_4321)  
• Uterine Cervix (UBERON_0000002)   HEp-2 (CVCL_1906)  

Reported structure

• O-Linked / Core 0 / GalNAc
• O-Linked / O-GlcNAc / GlcNAc(b

Composition

• HexNAc:1 (avg mass : 221.2103 )

Disease

• Adenocarcinoma (DOID:299)

Reference

• Neutralization of pH in the Golgi apparatus causes redistribution of glycosyltransferases and changes in the O-glycosylation of mucins. (2001 - Axelsson M, Karlsson N, Steel D, Ouwendijk J, Nilsson T, Hansson G) / Status : Reviewed
• Purification and characterization of the MUC1 mucin-type glycoprotein, epitectin, from human urine: structures of the major oligosaccharide alditols. (1998 - Bhavanandan V, Zhu Q, Yamakami K, Dilulio N, Nair S, Capon C, Lemoine J, Fournet B) / Status : Reviewed
• A subpopulation of estrogen receptors are modified by O-linked N-acetylglucosamine. (1997 - Jiang M, Hart G) / Status : Reviewed
• Chemical structure of epiglycanin, the major glycoprotein of the TA3-Ha ascites cell. The carbohydrate chains. (1979 - van den Eijnden D, Evans N, Codington J, Reinhold V, Silber C, Jeanloz R) / Status : Reviewed
• Immunochemical and chemical investigations of the structure of glycoprotein fragments obtained from epiglycanin, a glycoprotein at the surface of the TA3-Ha cancer cell. (1975 - Codington J, Linsley K, Jeanlot R) / Status : Reviewed

Reported glycosite

• Estrogen receptor / Homo sapiens
  •        Undefined site
• Mucin-1 / Homo sapiens
  •        Undefined site
• Unspecified mucin / Homo sapiens
  •        Undefined site
• Epiglycanin / Mus musculus
  •        Undefined site

Mass spectrometry observed peptide