Title Year Authors Journal Status External references Biological associations
Chemical structure of epiglycanin, the major glycoprotein of the TA3-Ha ascites cell. The carbohydrate chains. 1979 van den Eijnden D, Evans N, Codington J, Reinhold V, Silber C, Jeanloz R J Biol Chem Reviewed

    Mass spectrometry observed peptide

Structure determination of oligosaccharides isolated from A+, H+ and A-H- hog-submaxillary-gland mucin glycoproteins, by 360-MHz 1H-NMR spectroscopy, permethylation analysis and mass spectrometry. 1981 van Halbeek H, Dorland L, Haverkamp J, Veldink G, Vliegenthart J, Fournet B, Ricart G, Montreuil J, Gathmann W, Aminoff D Eur J Biochem Reviewed

    Protein

  • Mucin / Sus scrofa    

    Disease

    Mass spectrometry observed peptide

Extensive Crosstalk Between O-GlcNAcylation and Phosphorylation Regulates Cytokinesis 2010 Zihao Wang, Namrata D Udeshi, Chad Slawson, Philip D Compton, Kaoru Sakabe, Win D Cheung, Jeffrey Shabanowitz, Donald F Hunt, Gerald W Hart Sci Signal Reviewed

    Disease

Site-specific GlcNAcylation of Human Erythrocyte Proteins: Potential Biomarker(s) for Diabetes 2009 Zihao Wang, Kyoungsook Park, Frank Comer, Linda C Hsieh-Wilson, Christopher D Saudek, Gerald W Hart Diabetes Reviewed

    Disease

Identification of O-linked N-acetylglucosamine modification of ankyrinG isoforms targeted to nodes of Ranvier. 1996 Zhang X, Bennett V J Biol Chem Reviewed

    Protein

  • Ankyrin 3 / Bos taurus    E1BNC9

    Disease

    Mass spectrometry observed peptide

Reduction of O-linked N-acetylglucosamine-modified assembly protein-3 in Alzheimer's disease. 1998 Yao P, Coleman P J Neurosci Reviewed

    Mass spectrometry observed peptide

Intestinal glycoproteins of germfree rats. IV. Oligosaccharides obtained by chemical degradation of a water-soluble glycoprotein fraction. 1975 Wold J, Smestad B, Midtvedt T Acta Chem Scand B Reviewed

    Protein

  • Mucin / Rattus norvegicus    

    Disease

    Mass spectrometry observed peptide

Characterization of oligosaccharide structures on a chimeric respiratory syncytial virus protein expressed in insect cell line Sf9. 1991 Wathen M, Aeed P, Elhammer A Biochemistry Reviewed

    Disease

    Mass spectrometry observed peptide

Carbohydrate structures of bovine submaxillary mucin. 1986 Tsuji T, Osawa T Carbohydr Res Reviewed

    Protein

  • Mucin / Bos taurus    

    Disease

    Mass spectrometry observed peptide

Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surfaces of intact lymphocytes. Evidence for O-linked GlcNAc. 1984 Torres C, Hart G J Biol Chem Reviewed

    Disease

    Mass spectrometry observed peptide

Intestinal mucins from cystic fibrosis mice show increased fucosylation due to an induced Fucalpha1-2 glycosyltransferase. 2002 Thomsson KA, Hinojosa-Kurtzberg M, Axelsson KA, Domino SE, Lowe JB, Gendler SJ, Hansson GC Biochem J Reviewed

    Protein

  • Muc2 / Mus musculus    

    Mass spectrometry observed peptide

Structural studies on human erythrocyte glycoproteins. Alkali-labile oligosaccharides. 1969 Thomas D, Winzler R J Biol Chem Reviewed

    Disease

    Mass spectrometry observed peptide

Modification of Histones by Sugar β-N-acetylglucosamine (GlcNAc) Occurs on Multiple Residues, Including Histone H3 Serine 10, and Is Cell Cycle-Regulated 2011 Suisheng Zhang, Kevin Roche, Heinz-Peter Nasheuer, Noel Francis Lowndes J Biol Chem Reviewed

    Protein

  • Histone H3 / Homo sapiens    P68431

    Disease

Primary structure and function of novel O-glycosylated hirudins from the leech Hirudinaria manillensis. 1992 Steiner V, Knecht R, Brnsen K, Gassmann E, Stone S, Raschdorf F, Schlaeppi J, Maschler R Biochemistry Reviewed

    Disease

    Mass spectrometry observed peptide

Cysteine Aminoethylation Enables the Site-Specific Glycosylation Analysis of Recombinant Human Erythropoietin using Trypsin 2020 Steffen Lippold, Alexander Büttner, Matthew S.F. Choo, Michaela Hook, Coen J. de Jong, Terry Nguyen-Khuong, Markus Haberger, Dietmar Reusch, Manfred Wuhrer, Noortje de Haan Anal Chem Reviewed

    Disease

The serine-rich Entamoeba histolytica protein is a phosphorylated membrane protein containing O-linked terminal N-acetylglucosamine residues. 1995 Stanley Jr S, Tian K, Koester J, Li E J Biol Chem Reviewed

    Source

    Disease

    Mass spectrometry observed peptide

Identification of N-linked glycosylation and putative O-fucosylation, C-mannosylation sites in plasma derived ADAMTS13 2014 Sorvillo N, Kaijen PH, Matsumoto M, Fujimura Y, van der Zwaan C, Verbij FC, Pos W, Fijnheer R, Voorberg J, Meijer AB J Thromb Haemost Reviewed

    Disease

    Mass spectrometry observed peptide

Glycomic studies of Drosophila melanogaster embryos. 2006 Simon J North, Kate Koles, Caleb Hembd, Howard R Morris, Anne Dell, Vladislav M Panin, Stuart M Haslam Glycoconj J Reviewed

    Protein

    Disease

    Reported glycosite

    Mass spectrometry observed peptide

Mapping O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody 2011 Scott A Yuzwa, Anuj K Yadav, Yuliya Skorobogatko, Thomas Clark, Keith Vosseller, David J Vocadlo Amino acids Unreviewed

    Source

    Disease

A nuclear specific glycoprotein representative of a unique pattern of glycosylation. 1987 Schindler M, Hogan M, Miller R, DeGaetano D J Biol Chem Reviewed

    Disease

    Mass spectrometry observed peptide

Structural characterization of neutral oligosaccharides with blood-group A and H activity isolated from bovine submaxillary mucin. 1991 Savage A, D'Arcy S, Donoghue C Biochem J Reviewed

    Protein

  • Mucin / Bos taurus    

    Disease

    Mass spectrometry observed peptide

Detection of O-mannosyl glycans in rabbit skeletal muscle alpha-dystroglycan. 1998 Sasaki T, Yamada H, Matsumura K, Shimizu T, Kobata A, Endo T Biochim Biophys Acta Reviewed

    Composition

  • Hex:1 (avg mass : 180.1577 )

    Disease

    Mass spectrometry observed peptide

Electron Transfer Dissociation (ETD): The Mass Spectrometric Breakthrough Essential for O-GlcNAc Protein Site Assignments-A Study of the O-GlcNAcylated Protein Host Cell Factor C1 2013 Samuel A Myers, Salima Daou, El Bachir Affar, Al Burlingame Proteomics Reviewed

    Disease

Vertebrate lens alpha-crystallins are modified by O-linked N-acetylglucosamine. 1992 Roquemore E, Dell A, Morris H, Panico M, Reason A, Savoy L, Wistow G, Zigler J, Earles B, Hart G J Biol Chem Reviewed

    Disease

    Mass spectrometry observed peptide

Bovine lens alpha-crystalline subunits are modified by O-linked GlcNAc. 1991 Roquemore E, Dell A, Hart G Glycoconj J Reviewed

    Disease

    Mass spectrometry observed peptide

Community Evaluation of Glycoproteomics Informatics Solutions Reveals High-Performance Search Strategies for Glycopeptide Analysis 2021 Rebeca Kawahara, Kathirvel Alagesan, Marshall Bern, Meng Bo, Weiqian Cao, Robert J Chalkley, Kai Cheng, Matthew S. Choo, Nathan Edwards, Radoslav Goldman, Marcus Hoffmann, Yingwei Hu, Yifan Huang, Jin Young Kim, Doron Kletter, Benoit Liquet-Weiland, Mingqi Liu, Yehia Mechref, Sriram Neelamegham, Terry Nguyen-Khuong, Jonas Nilsson, Adam Pap, Gun Wook Park, Benjamin L. Parker, Cassandra L. Pegg, Josef M. Penninger, Toan K. Phung, Markus Pioch, Erdmann Rapp, Enes Sakalli, Miloslav Sanda, Benjamin L. Schulz, Nichollas Scott, Georgy Sofronov, Johannes Stadlmann, Sergey Vakhrushev, Christina Woo, Hung-Yi Wu, Pengyuan Yang, Wantao Ying, Zhang Yong, Hui Zhang, Jingfu Zhao, Joseph Zaia, Stuart M. Haslam, Giuseppe Palmisano, Jong Shin Yoo, Goran Larson, Kai-Hooi Khoo, Katalin F. Medzihradszky, Daniel Kolarich, Nicolle H. Packer, and Morten Thaysen-Andersen bioRxiv Reviewed

    Reported structure

    Disease

Identification of O-GlcNAc attachment sites in transcription factors. 1991 Reason A, Dell A, Morris H, Panico M, Treisman R, Marais R, Hart G, Haltiwanger R Glycoconj J Reviewed

    Mass spectrometry observed peptide

Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity. 1998 Prakobphol A, Thomsson K, Hansson G, Rosen S, Singer M, Phillips N, Medzihradszky K, Burlingame A, Leffler H, Fisher S Biochemistry Reviewed

    Protein

  • Mucin-7 / Homo sapiens    Q8TAX7

    Disease

    Mass spectrometry observed peptide

Sugar sequences of allergenically active oligosaccharide alcohols isolated from a large-molecular-size sea squirt antigen termed H-antigen. 1989 Ohta M, Shigeta S, Ono K, Takao T, Shimonishi Y, Oka S Arch Biochem Biophys Reviewed

    Protein

  • H-antigen / Styela plicata    

    Disease

    Mass spectrometry observed peptide

Schistosoma mansoni synthesizes glycoproteins containing terminal O-linked N-acetylglucosamine residues. 1987 Nyame K, Cummings R, Damian R J Biol Chem Reviewed

    Source

    Disease

    Mass spectrometry observed peptide

Characterization of the N- and O-linked oligosaccharides in glycoproteins synthesized by Schistosoma mansoni schistosomula. 1988 Nyame K, Cummings R, Damian R J Parasitol Reviewed

    Source

    Disease

    Mass spectrometry observed peptide

Immunochemical studies on blood groups. Immunochemical properties of B-active and non-B-active blood group substances from horse gastric mucosae and the relative size distributions of oligosaccharides liberated by base-borohydride. 1976 Newman W, Kabat E Arch Biochem Biophys Reviewed

    Protein

  • Mucin / Equus caballus    

    Disease

    Mass spectrometry observed peptide

Relative accessibility of N-acetylglucosamine in trimers of the adenovirus types 2 and 5 fiber proteins. 1990 Mullis K, Haltiwanger R, Hart G, Marchase R, Engler J J Virol Reviewed

    Mass spectrometry observed peptide

Multiple O-glycoforms on the spore coat protein SP96 in Dictyostelium discoideum. Fuc(alpha1-3)GlcNAc-alpha-1-P-Ser is the major modification. 2000 Mreyen M, Champion A, Srinivasan S, Karuso P, Williams K, Packer N J Biol Chem Reviewed

    Disease

    Mass spectrometry observed peptide

Structural analysis of oligosaccharide-alditols released by reductive beta-elimination from the jelly coats of the anuran Bufo arenarum. 1998 Morelle W, Cabada M, Strecker G Eur J Biochem Reviewed

    Protein

  • Mucin / Bufo arenarum    

    Disease

    Mass spectrometry observed peptide

Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules. 2000 Moloney D, Shair L, Lu F, Xia J, Locke R, Matta K, Haltiwanger R J Biol Chem Reviewed

    Protein

  • Notch 1 / Cricetulus griseus    

    Disease

    Mass spectrometry observed peptide

O-GlcNAc Regulates FoxO Activation in Response to Glucose 2008 Michael P Housley, Joseph T Rodgers, Namrata D Udeshi, Timothy J Kelly, Jeffrey Shabanowitz, Donald F Hunt, Pere Puigserver, Gerald W Hart J Biol Chem Reviewed
Nuclear localization of an O-glycosylated protein phosphotyrosine phosphatase from human cells. 1991 Meikrantz W, Smith D, Sladicka M, Schlegel R J Cell Sci Reviewed

    Mass spectrometry observed peptide

SV40 large T antigen is modified with O-linked N-acetylglucosamine but not with other forms of glycosylation. 1998 Medina L, Grove K, Haltiwanger R Glycobiology Reviewed

    Disease

    Mass spectrometry observed peptide

Neutral core oligosaccharides of bovine submaxillary mucin--use of lead tetraacetate in the cold for establishing branch positions. 1998 Martensson S, Levery S, Fang T, Bendiak B Eur J Biochem Reviewed

    Protein

  • Mucin / Bos taurus    

    Disease

    Mass spectrometry observed peptide

Immunochemical studies on blood groups. Structures and immunochemical properties of oligosaccharides from two fractions of blood group substance from human ovarian cyst fluid differing in B, I, and i activities and reactivity toward concanavalin A. 1976 Maisonrouge-McAuliffe F, Kabat E Arch Biochem Biophys Reviewed

    Mass spectrometry observed peptide

Structural analysis of the oligosaccharide-alditols released by reductive beta-elimination from oviducal mucins of Rana temporaria. 1997 Maes E, Florea D, Delplace F, Lemoine J, Plancke Y, Strecker G Glycoconj J Reviewed

    Protein

  • Mucin / Rana temporaria    

    Disease

    Mass spectrometry observed peptide

O-N-acetyl-D-glucosamine Moiety on Discrete Peptide of Multiple Protein 4.1 Isoforms Regulated by Alternative Pathways 1989 M Inaba, Y Maede J Biol Chem Reviewed

    Protein

  • Protein 4.1 / Homo sapiens    P11171

    Disease

Synapsins contain O-linked N-acetylglucosamine. 1991 Luthi T, Haltiwanger R, Greengard P, Bahler M J Neurochem Reviewed

    Protein

  • Synapsin-1 / Bos taurus    P17599

    Disease

    Mass spectrometry observed peptide

Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells. 1996 Lloyd KO, Burchell J, Kudryashov V, Yin BW, Taylor-Papadimitriou J J Biol Chem Reviewed

    Protein

  • Mucin-1 / Homo sapiens    P15941

    Mass spectrometry observed peptide

Structural studies on cutinase, a glycoprotein containing novel amino acids and glucuronic acid amide at the N terminus. 1980 Lin T, Kolattukudy P Eur J Biochem Reviewed

    Source

    Disease

    Mass spectrometry observed peptide

Altered sialylation of CD45 in HIV-1-infected T lymphocytes. 1994 Lefebvre J, Giordanengo V, Doglio A, Cagnon L, Breittmayer J, Peyron J, Lesimple J Virology Reviewed

    Mass spectrometry observed peptide

Identification and mutational analysis of the glycosylation sites of human keratin 18. 1995 Ku N, Omary M J Biol Chem Reviewed

    Mass spectrometry observed peptide

Glycosylation analysis and protein structure determination of murine fetal antigen 1 (mFA1)--the circulating gene product of the delta-like protein (dlk), preadipocyte factor 1 (Pref-1) and stromal-cell-derived protein 1 (SCP-1) cDNAs. 1997 Krogh T, Bachmann E, Teisner B, Skjdt K, Hjrup P Eur J Biochem Reviewed

    Disease

    Mass spectrometry observed peptide

Mucin-type glycoprotein from Drosophila melanogaster embryonic cells: characterization of carbohydrate component. 1996 Kramerov A, Arbatsky N, Rozovsky Y, Mikhaleva E, Polesskaya O, Gvozdev V, Shibaev V FEBS Lett Reviewed

    Disease

    Mass spectrometry observed peptide