Increasing the Coverage of a Mass Spectral Library of Milk Oligosaccharides Using a Hybrid-Search-Based Bootstrapping Method and Milks from a Wide Variety of Mammals (2020)
Concepcion Africano Remoroza, Yuxue Liang, Tytus D. Mak, Yuri Mirokhin, Sergey L. Sheetlin, Xiaoyu Yang, Joice V. San Andres, Michael L. Power, and Stephen E. Stein
Anal Chem, 2020 vol.92(15):10316-10326
SNFG,
Text,
Oxford
taxonomy (1)
protein (0)
source (1)
structure (70)
composition (30)
disease (0)
reference (1)
site (0)
peptide (0)
- Homo sapiens (Human)
Taxonomy
Protein
- Milk (UBERON_0001913)
Source
- Free / Lactose / Structure 9214
- Free / Lactose / Structure 9158
- Free / Lactose / Structure 9219
- Free / Lactose / Structure 9155
- Free / Lactose / Structure 9215
- Free / Lactose / [Gal(b1-4)GlcNAc(b1-6)][Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)]Gal(b1-4)Glc(b1-
- Free / Lactose / Structure 9217
- Free / Lactose / Structure 9218
- Free / Lactose / Structure 9216
- Free / Lactose / Structure 9152
- Free / Lactose / Structure 9220
- Free / Lactose / Structure 9221
- Free / Lactose / Structure 9222
- Free / Lactose / [Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-6)][Gal(b1-3)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-
- Free / Lactose / Structure 9199
- Free / Lactose / Structure 9207
- Free / Lactose / Structure 9154
- Free / Lactose / Structure 9157
- Free / Lactose / Structure 9212
- Free / Lactose / Structure 9208
- Free / Lactose / Structure 9156
- Free / Lactose / Structure 9197
- Free / Lactose / Structure 9200
- Free / Lactose / Structure 9201
- Free / Lactose / Structure 9202
- Free / Lactose / Structure 9223
- Free / Lactose / Structure 9153
- Free / Lactose / [[Gal(b1-4)GlcNAc(b1-6)][Gal(b1-3)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-6)][Gal(b1-3)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-
- Free / Lactose / Structure 9210
- Free / Lactose / Structure 9198
- Free / Lactose / Structure 9204
- Free / Lactose / Structure 9205
- Free / Lactose / Structure 9159
- Free / Lactose / Structure 9160
- Free / Lactose / Structure 9206
- Free / Lactose / Structure 9209
- Free / Lactose / Structure 9161
- Free / Lactose / Structure 9162
- Free / Lactose / Structure 9166
- Free / Lactose / Structure 9167
- Free / Lactose / Structure 9196
- Free / Lactose / [[Gal(b1-4)GlcNAc(b1-6)][Gal(b1-3)GlcNAc(b1-3)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-6)][[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)]Gal(b1-4)Glc(b1-
- Free / Lactose / Structure 9168
- Free / Lactose / Structure 9169
- Free / Lactose / Structure 9170
- Free / Lactose / Structure 9171
- Free / Lactose / Structure 9173
- Free / Lactose / Structure 9176
- Free / Lactose / Structure 9177
- Free / Lactose / Structure 9178
- Free / Lactose / [[Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-6)][[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-6)][[Fuc(a1-2)]Gal(b1-3)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-
- Free / Lactose / Structure 9174
- Free / Lactose / Structure 9175
- Free / Lactose / Structure 9179
- Free / Lactose / Structure 9180
- Free / Lactose / Structure 9181
- Free / Lactose / Structure 9182
- Free / Lactose / Structure 9183
- Free / Lactose / Structure 9184
- Free / Lactose / Structure 9185
- Free / Lactose / Structure 9186
- Free / Lactose / Structure 9187
- Free / Lactose / Structure 9188
- Free / Lactose / Structure 9189
- Free / Lactose / Structure 9190
- Free / Lactose / Structure 9191
- Free / Lactose / Structure 9192
- Free / Lactose / Structure 9193
- Free / Lactose / Structure 9194
- Free / Lactose / Structure 9195
Reported structure
- Hex:3 HexNAc:2 (avg mass : 910.8325 )
- Hex:4 HexNAc:1 dHex:1 (avg mass : 1015.9229 )
- Hex:4 HexNAc:2 dHex:1 (avg mass : 1219.1179 )
- Hex:4 HexNAc:2 dHex:4 (avg mass : 1657.5469 )
- Hex:5 (avg mass : 828.7273 )
- Hex:5 HexNAc:2 (avg mass : 1235.1173 )
- Hex:5 HexNAc:2 dHex:1 (avg mass : 1381.2603 )
- Hex:5 HexNAc:2 dHex:2 (avg mass : 1527.4033 )
- Hex:5 HexNAc:2 dHex:3 (avg mass : 1673.5463 )
- Hex:5 HexNAc:3 (avg mass : 1438.3123 )
- Hex:5 HexNAc:3 dHex:1 (avg mass : 1584.4553 )
- Hex:5 HexNAc:3 dHex:1 NeuAc:1 (avg mass : 1875.7132 )
- Hex:5 HexNAc:3 dHex:2 (avg mass : 1730.5983 )
- Hex:5 HexNAc:3 dHex:4 (avg mass : 2022.8843 )
- Hex:6 HexNAc:2 (avg mass : 1397.2597 )
- Hex:6 HexNAc:3 dHex:1 (avg mass : 1746.5977 )
- Hex:6 HexNAc:4 (avg mass : 1803.6497 )
- Hex:6 HexNAc:4 dHex:1 (avg mass : 1949.7927 )
- Hex:6 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2241.0506 )
- Hex:6 HexNAc:4 dHex:2 (avg mass : 2095.9357 )
- Hex:6 HexNAc:4 dHex:3 (avg mass : 2242.0787 )
- Hex:6 HexNAc:4 dHex:4 (avg mass : 2388.2217 )
- Hex:7 (avg mass : 1153.0121 )
- Hex:7 HexNAc:5 dHex:1 (avg mass : 2315.1301 )
- Hex:7 HexNAc:5 dHex:2 (avg mass : 2461.2731 )
- Hex:7 HexNAc:5 dHex:3 (avg mass : 2607.4161 )
- Hex:7 HexNAc:5 dHex:4 (avg mass : 2753.5591 )
- Hex:8 (avg mass : 1315.1545 )
- Hex:8 HexNAc:6 dHex:2 (avg mass : 2826.6105 )
- Hex:8 HexNAc:6 dHex:3 (avg mass : 2972.7535 )
Composition
Disease
Reported glycosite
Mass spectrometry observed peptide
-
- Free / Lactose
(avg mass : 828.7273)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 910.8325)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 910.8325)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1015.9229)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1153.0121)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1219.1179)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1219.1179)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1235.1173)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1315.1545)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1381.2603)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1381.2603)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1381.2603)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1397.2597)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1438.3123)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1438.3123)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1438.3123)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1527.4033)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1527.4033)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1584.4553)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1657.5469)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1673.5463)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1730.5983)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1730.5983)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1730.5983)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1730.5983)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1730.5983)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1746.5977)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1803.6497)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1803.6497)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1875.7132)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1875.7132)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1875.7132)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1949.7927)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1949.7927)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 1949.7927)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2022.8843)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2095.9357)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2095.9357)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2095.9357)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2095.9357)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2241.0506)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2242.0787)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2242.0787)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2242.0787)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2242.0787)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2242.0787)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2242.0787)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2315.1301)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2315.1301)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2315.1301)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2388.2217)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2388.2217)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2388.2217)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2461.2731)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2461.2731)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2461.2731)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2461.2731)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2607.4161)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2607.4161)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2607.4161)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2607.4161)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2607.4161)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2607.4161)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2753.5591)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2753.5591)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2753.5591)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2753.5591)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2826.6105)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2972.7535)
- Milk (UBERON_0001913)
-
- Free / Lactose
(avg mass : 2972.7535)
- Milk (UBERON_0001913)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2972.7535)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2972.7535)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2826.6105)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2753.5591)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2753.5591)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2753.5591)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2753.5591)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2607.4161)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2607.4161)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2607.4161)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2607.4161)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2607.4161)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2607.4161)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2461.2731)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2461.2731)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2461.2731)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2461.2731)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2388.2217)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2388.2217)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2388.2217)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2315.1301)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2315.1301)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2315.1301)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2242.0787)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2242.0787)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2242.0787)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2242.0787)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2242.0787)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2242.0787)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2241.0506)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2095.9357)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2095.9357)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2095.9357)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2095.9357)
Source
Reported glycosite
- Free / Lactose
(avg mass : 2022.8843)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1949.7927)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1949.7927)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1949.7927)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1875.7132)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1875.7132)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1875.7132)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1803.6497)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1803.6497)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1746.5977)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1730.5983)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1730.5983)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1730.5983)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1730.5983)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1730.5983)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1673.5463)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1657.5469)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1584.4553)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1527.4033)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1527.4033)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1438.3123)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1438.3123)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1438.3123)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1397.2597)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1381.2603)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1381.2603)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1381.2603)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1315.1545)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1235.1173)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1219.1179)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1219.1179)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1153.0121)
Source
Reported glycosite
- Free / Lactose
(avg mass : 1015.9229)
Source
Reported glycosite
- Free / Lactose
(avg mass : 910.8325)
Source
Reported glycosite
- Free / Lactose
(avg mass : 910.8325)
Source
Reported glycosite
- Free / Lactose
(avg mass : 828.7273)
