Leishmania major

Taxonomy

• Leishmania major

Protein

• Gp96/92 / Leishmania major
• Leishmanolysin / Leishmania major    P08148

Source

• Cytoplasm (GO_0005737)  

Reported structure

• N-Linked/O-Linked / Truncated If N-Linked / GlcNAc
• N-Linked / High-Mannose / Man(a1-2)Man(a1-2)Man(a1-3)[Man(a1-3)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
• N-Linked / High-Mannose / Glc(a1-3)Man(a1-2)Man(a1-2)Man(a1-3)[Man(a1-3)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• HexNAc:1 (avg mass : 221.2103 )
• Hex:6 HexNAc:2 (avg mass : 1397.2597 )
• Hex:7 HexNAc:2 (avg mass : 1559.4021 )

Disease

Reference

• A unique, terminally glucosylated oligosaccharide is a common feature on Leishmania cell surfaces (1997 - Funk VA, Thomas-Oates JE, Kielland SL, Bates PA, Olafson RW) / Status : Reviewed
• Identification, characterisation and genomic cloning of a O-linked N-acetylglucosamine-containing cytoplasmic Leishmania glycoprotein. (1993 - Handman E, Barnett L, Osborn A, Goding J, Murray P) / Status : Reviewed

Reported glycosite

• Gp96/92 / Leishmania major
  •        Undefined site
• Leishmanolysin / Leishmania major
  •        Undefined site

Mass spectrometry observed peptide