Structure

Taxonomy

• Homo sapiens (Human)
• Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)

Protein

• Erythropoietin / Homo sapiens    P01588
• Recombinant Spike glycoprotein (CHO) - RBD domain / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)    P0DTC2
• Recombinant Spike glycoprotein (HEK293) - RBD domain / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)    P0DTC2

Source

• Ovary (UBERON_0000992)   CHO (CVCL_0213)  
• CHO (CVCL_0213)  
• HEK293 (CVCL_0045)  

Reported structure

• O-Linked / Core 1 / Structure 9312

Composition

• HexNAc:1 NeuAc:1 (avg mass : 512.4682 )

Disease

• COVID-19 (DOID:0080600)

Reference

• Structural and functional characterization of SARS-CoV-2 RBD domains produced in mammalian cells (2021 - Christoph Gstöttner, Tao Zhang, Anja Resemann, Sophia Ruben, Stuart Pengelley, Detlev Suckau, Tim Welsink, Manfred Wuhrer, Elena Domínguez-Vega) / Status : Reviewed
• Cysteine Aminoethylation Enables the Site-Specific Glycosylation Analysis of Recombinant Human Erythropoietin using Trypsin (2020 - Steffen Lippold, Alexander Büttner, Matthew S.F. Choo, Michaela Hook, Coen J. de Jong, Terry Nguyen-Khuong, Markus Haberger, Dietmar Reusch, Manfred Wuhrer, Noortje de Haan) / Status : Reviewed

Reported glycosite

• Erythropoietin / Homo sapiens
  •        Ser-153
• Recombinant Spike glycoprotein (CHO) - RBD domain / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
  •        Thr-323
• Recombinant Spike glycoprotein (HEK293) - RBD domain / Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
  •        Thr-323

Mass spectrometry observed peptide

• EAISPPDAASAAPLR (15aa)
  •    P01588    Ser-153     Erythropoietin / Homo sapiens

RES
1b:a-dgal-HEX-1:5
2b:x-dgro-dgal-NON-2:6|1:a|2:keto|3:d
3s:n-acetyl
4s:n-acetyl
LIN
1:1o(-1+2)2d
2:2d(5+1)3n
3:1d(2+1)4n