GlyConnect

taxonomy (1) protein (1) source (1) structure (1) composition (1) disease (2) reference (1) site (9) peptide (0)

Taxonomy

Homo sapiens (Human)

Protein

Proteoglycan 4 (lubricin) / Homo sapiens Q92954

Source

Synovial Fluid (UBERON_0001090)

Reported structure

O-Linked / Core 1 / Gal(b1-3)GalNAc(a + "Neu5Ac(a"

Composition

Hex:1 HexNAc:1 NeuAc:1 (avg mass : 674.6106 )

Disease

Arthritis, Rheumatoid (DOID:7148)
Osteoarthritis (DOID:8398)

Reference

The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis (2014 - Ali L, Flowers SA, Jin C, Bennet EP, Ekwall AK, Karlsson NG) / Status : Reviewed

Reported glycosite

Proteoglycan 4 (lubricin) / Homo sapiens
- Ser-123
- Thr-277
- Thr-310
- Ser-317
- Thr-324
- Thr-332
- Thr-676
- Ser-892
- Thr-900

Mass spectrometry observed peptide

- O-Linked / Core 1 (avg mass : 674.6106)