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  • Structure

Structure

Details for this Complex / N-Linked glycan structure

SNFG, Text, Oxford
Taxonomy (1) Protein (2) Source (1) Structure (1) Composition (1) Disease (0) Site (3) Peptide (0)

    Taxonomy

  • Homo sapiens (Human)

    Protein

  • Glycoprotein hormones alpha chain - choriogonadotropin / Homo sapiens    P01215
  • Lutropin beta chain / Homo sapiens    P01229

    Source

  • Pituitary Gland (UBERON_0000007)  

    Reported structure

  • N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuAc(a2-6)GalNAc(b1-4)GlcNAc(b1-2)Man(a1-3)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)GlcNAc

    Composition

  • Hex:4 HexNAc:6 NeuAc:2 (avg mass : 2468.2707 )

    Disease

    Reported glycosite

  • Lutropin beta chain / Homo sapiens :
    •        Asn-50
  • Glycoprotein hormones alpha chain - choriogonadotropin / Homo sapiens :
    •        Asn-76
    •        Asn-102

    Mass spectrometry validated peptide

  • No image
    • N-Linked / Complex (avg mass : 2468.2707 )
    • Site (3)

        Reported glycosite

      • Lutropin beta chain / Homo sapiens :
        •        Asn-50
      • Glycoprotein hormones alpha chain - choriogonadotropin / Homo sapiens :
        •        Asn-76
        •        Asn-102

Glycan references

GlyTouCan : G39540XG


Composition

Hex:4 HexNAc:6 NeuAc:2


IUPAC

NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)[NeuAc(a2-6)GalNAc(b1-4)GlcNAc(b1-2)Man(a1-3)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)GlcNAc

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:b-dglc-HEX-1:5
4s:n-acetyl
5b:b-dman-HEX-1:5
6b:a-dman-HEX-1:5
7b:b-dglc-HEX-1:5
8s:n-acetyl
9b:b-dgal-HEX-1:5
10s:n-acetyl
11b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
12s:n-acetyl
13b:b-dglc-HEX-1:5
14s:n-acetyl
15b:a-dman-HEX-1:5
16b:b-dglc-HEX-1:5
17s:n-acetyl
18b:b-dgal-HEX-1:5
19b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
20s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(4+1)3d
3:3d(2+1)4n
4:3o(4+1)5d
5:5o(3+1)6d
6:6o(2+1)7d
7:7d(2+1)8n
8:7o(4+1)9d
9:9d(2+1)10n
10:9o(6+2)11d
11:11d(5+1)12n
12:5o(4+1)13d
13:13d(2+1)14n
14:5o(6+1)15d
15:15o(2+1)16d
16:16d(2+1)17n
17:16o(4+1)18d
18:18o(3+2)19d
19:19d(5+1)20n


References (1)

NMR investigations of the N-linked oligosaccharides at individual glycosylation sites of human lutropin. (1991)
Weisshaar G, Hiyama J, Renwick A, Nimtz M
Pubmed : 1991473  
Status : Reviewed

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