Structure

Glycan references

GlyTouCan : G64973KT

UniCarb-DB :

• 24
• 42
• 76
• 100
• 187
• 279
• 2638
• 2675
• 2777
• 3051
• 3496
• 3659

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Composition

Hex:2 HexNAc:2

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IUPAC

Gal(b1-4)GlcNAc(b1-6)[Gal(b1-3)]GalNAc

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:b-dglc-HEX-1:5
5s:n-acetyl
6b:b-dgal-HEX-1:5
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(6+1)4d
4:4d(2+1)5n
5:4o(4+1)6d

References (46)

The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis (2014)
Ali L, Flowers SA, Jin C, Bennet EP, Ekwall AK, Karlsson NG
Pubmed : 25187573   DOI : 10.1074/mcp.M114.040865
Status : Reviewed

Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans. (2003)
Dell A, Chalabi S, Easton RL, Haslam SM, Sutton-Smith M, Patankar MS, Lattanzio F, Panico M, Morris HR, Clark GF
Pubmed : 14673092   DOI : 10.1073/pnas.2635507100
Status : Reviewed

Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation. (2002)
Muller S, Hanisch FG
Pubmed : 12000758   DOI : 10.1074/jbc.M202921200
Status : Reviewed

In vivo glycosylation of mucin tandem repeats (2001)
Silverman, Parry, Sutton-Smith, Burdick, McDermott, Reid, Batra, Morris, Hollingsworth, Dell, Harris
Pubmed : 11445551  
Status : Reviewed

O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organization of the enzyme. (2000)
Mattu T, Royle L, Langridge J, Wormald M, Van den Steen P, Van Damme J, Opdenakker G, Harvey D, Dwek R, Rudd P
Pubmed : 11123894  
Status : Reviewed

High prevalence of 2-mono- and 2,6-di-substituted manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis. (1999)
Chai W, Yuen C, Kogelberg H, Carruthers R, Margolis R, Feizi T, Lawson A
Pubmed : 10469154  
Status : Reviewed

Purification and characterization of the MUC1 mucin-type glycoprotein, epitectin, from human urine: structures of the major oligosaccharide alditols. (1998)
Bhavanandan V, Zhu Q, Yamakami K, Dilulio N, Nair S, Capon C, Lemoine J, Fournet B
Pubmed : 9530955  
Status : Reviewed

Structural study of the O-linked sugar chains of human leukocyte tyrosine phosphatase CD45. (1998)
Furukawa K, Funakoshi Y, Autero M, Horejsi V, Kobata A, Gahmberg C
Pubmed : 9492296  
Status : Reviewed

Structure of the O-glycopeptides isolated from bovine milk component PP3. (1998)
Coddeville B, Girardet J, Plancke Y, Campagna S, Linden G, Spik G
Pubmed : 9613824  
Status : Reviewed

Carbohydrate and peptide structure of the alpha- and beta-subunits of human chorionic gonadotropin from normal and aberrant pregnancy and choriocarcinoma. (1997)
Elliott M, Kardana A, Lustbader J, Cole L
Pubmed : 9449027   DOI : 10.1007/BF02778058
Status : Reviewed

Structural analysis of oligosaccharide-alditols released by reductive beta-elimination from oviducal mucins of Bufo bufo: characterization of the carbohydrate sequence Gal(alpha1-3)GalNAc(alpha1-3)[Fuc(alpha1-2)]Gal. (1997)
Morelle W, Strecker G
Pubmed : 9376680  
Status : Reviewed

Isolation and characterization of ovarian cancer antigen CA 125 using a new monoclonal antibody (VK-8): identification as a mucin-type molecule. (1997)
Lloyd K, Yin B, Kudryashov V
Pubmed : 9180155  
Status : Reviewed

Structure of the O-linked oligosaccharides from a major thyroid cell surface glycoprotein. (1997)
Edge A, Spiro R
Pubmed : 9210648   DOI : 10.1006/abbi.1997.0143
Status : Reviewed

Structures of the O-glycans on P-selectin glycoprotein ligand-1 from HL-60 cells. (1996)
Wilkins P, McEver R, Cummings R
Pubmed : 8702529  
Status : Reviewed

The immunologically reactive O-linked polysaccharide chains derived from circulating cathodic antigen isolated from the human blood fluke Schistosoma mansoni have Lewis x as repeating unit. (1994)
van Dam G, Bergwerff A, Thomas-Oates J, Rotmans J, Kamerling J, Vliegenthart J, Deelder A
Pubmed : 7925469  
Status : Reviewed

O-glycosylation mimics N-glycosylation in the 16-KDa fragment of bovine pro-opiomelanocortin. The major O-glycan attached to Thr-45 carries SO4-4GalNAc beta 1-4GlcNAc beta 1-, which is the archetypal non-reducing epitope in the N-glycans of pituitary glycohormones. (1994)
Siciliano R, Morris H, Bennett H, Dell A
Pubmed : 7507111  
Status : Reviewed

Assignment of O-glycan attachment sites to the hinge-like regions of human lysosomal membrane glycoproteins lamp-1 and lamp-2. (1993)
Carlsson S, Lycksell P, Fukuda M
Pubmed : 8323299   DOI : 10.1006/abbi.1993.1322
Status : Reviewed

Carbohydrate structure of Marburg virus glycoprotein. (1992)
Geyer H, Will C, Feldmann H, Klenk H, Geyer R
Pubmed : 1421752  
Status : Reviewed

The broad diversity of neutral and sialylated oligosaccharides derived from human salivary mucins. (1992)
Klein A, Carnoy C, Wieruszeski J, Strecker G, Strang A, van Halbeek H, Roussel P, Lamblin G
Pubmed : 1627559  
Status : Reviewed

Neutral oligosaccharides of bovine submaxillary mucin. A combined mass spectrometry and 1H-NMR study. (1992)
Chai W, Hounsell E, Cashmore G, Rosankiewicz J, Bauer C, Feeney J, Feizi T, Lawson A
Pubmed : 1730232  
Status : Reviewed

Characterisation of minor tetra- to hepta-saccharides O-linked to human meconium glycoproteins by t.l.c.-m.s. microsequencing of neoglycolipid derivatives in conjunction with conventional m.s. and 1H-n.m.r. spectroscopy. (1991)
Lawson A, Hounsell E, Stoll M, Feeney J, Chai W, Rosankiewicz J, Feizi T
Pubmed : 1726196  
Status : Reviewed

Structural characterization of neutral oligosaccharides with blood-group A and H activity isolated from bovine submaxillary mucin. (1991)
Savage A, D'Arcy S, Donoghue C
Pubmed : 1718265  
Status : Reviewed

Altered glycosylation of human chorionic gonadotropin decreases its hormonal activity as determined by cyclic-adenosine 3',5'-monophosphate production in MA-10 cells. (1990)
Amano J, Nishimura R, Sato S, Kobata A
Pubmed : 1967025  
Status : Reviewed

Structures of O-glycosidically linked oligosaccharides isolated from human meconium glycoproteins. (1989)
Capon C, Leroy Y, Wieruszeski J, Ricart G, Strecker G, Montreuil J, Fournet B
Pubmed : 2731547  
Status : Reviewed

Primary structure of twenty three neutral and monosialylated oligosaccharides O-glycosidically linked to the human secretory immunoglobulin A hinge region determined by a combination of permethylation analysis and 400-MHz 1H-NMR spectroscopy. (1989)
Pierce-Cretel A, Decottignies J, Wieruszeski J, Strecker G, Montreuil J, Spik G
Pubmed : 2737211  
Status : Reviewed

Comparative study of the mucin-type sugar chains of human chorionic gonadotropin present in the urine of patients with trophoblastic diseases and healthy pregnant women. (1988)
Amano J, Nishimura R, Mochizuki M, Kobata A
Pubmed : 3335536  
Status : Reviewed

Primary structure of neutral oligosaccharides derived from respiratory-mucus glycoproteins of a patient suffering from bronchiectasis, determined by combination of 500-MHz 1H-NMR spectroscopy and quantitative sugar analysis. 1. Structure of 16 oligosaccharides having the Gal beta(1---3)GalNAc-ol cor (1988)
Klein A, Lamblin G, Lhermitte M, Roussel P, Breg J, Van Halbeek H, Vliegenthart J
Pubmed : 3345749  
Status : Reviewed

Chemical structure of neutral sugar chains isolated from human mature milk kappa-casein. (1988)
Saito T, Itoh T, Adachi S
Pubmed : 3342257  
Status : Reviewed

Determination of the structure of sulfated tetra- and pentasaccharides obtained by alkaline borohydride degradation of hen ovomucin. A fast atom bombardment-mass spectrometric and 1H-NMR spectroscopic study. (1987)
Strecker G, Wieruszeski J, Martel C, Montreuil J
DOI : 10.1007/BF01048366
Status : Reviewed

Structure of sialyl-oligosaccharides isolated from bronchial mucus glycoproteins of patients (blood group O) suffering from cystic fibrosis. (1987)
Breg J, Van Halbeek H, Vliegenthart J, Lamblin G, Houvenaghel M, Roussel P
Pubmed : 3665919  
Status : Reviewed

Structure of neutral oligosaccharides derived from mucus glycoproteins of human seminal plasma. (1986)
Hanisch F-G, Egge H, Peter-Katalinic J, Uhlenbruck G
Pubmed : 3956483  
Status : Reviewed

Structural analysis of the O-glycosidically linked core-region oligosaccharides of human meconium glycoproteins which express oncofoetal antigens. (1985)
Hounsell EF, Lawson AM, Feeney J, Gooi HC, Pickering NJ, Stoll MS, Lui SC, Feizi T
Pubmed : 2580706  
Status : Reviewed

Primary structures and Lewis blood-group-dependent expression of major sialylated saccharides from mucus glycoproteins of human seminal plasma. (1985)
Hanisch F, Egge H, Peter-Katalini J, Uhlenbruck G, Dienst C, Fangmann R
Pubmed : 4054112  
Status : Reviewed

Structures of the O-linked oligosaccharides of the major cell surface sialoglycoprotein of MAT-B1 and MAT-C1 ascites sublines of the 13762 rat mammary adenocarcinoma. (1984)
Hull S, Laine R, Kaizu T, Rodriguez I, Carraway K
Pubmed : 6715325  
Status : Reviewed

Structures of oligosaccharides cleaved by base-borohydride from an I, H and Lea active ovarian cyst glycoprotein. (1984)
Tanaka M, Dube V, Anderson B
Pubmed : 6712992  
Status : Reviewed

Purification and structures of oligosaccharide chains in swine trachea and Cowper's gland mucin glycoproteins. (1984)
Rana SS, Chandrasekaran EV, Kennedy J, Mendicino J
Pubmed : 6436240  
Status : Reviewed

Immunochemical studies on blood groups. Purification and characterization of radioactive 3H-reduced di- to hexasaccharides produced by alkaline beta-elimination-borohydride 3H reduction of Smith degraded blood group A active glycoproteins. (1984)
Wu A, Kabat E, Nilsson B, Zopf D, Gruezo F, Liao J
Pubmed : 6539332  
Status : Reviewed

The combination of normal-phase and reverse-phase high-pressure liquid chromatography with NMR for the isolation and characterization of oligosaccharide alditols from ovarian cyst mucins. (1984)
Dua V, Dube V, Bush C
Pubmed : 6487655  
Status : Reviewed

Structural characterization of neutral oligosaccharides of human midcycle cervical mucin. (1982)
Yurewicz E, Matsuura F, Moghissi K
Pubmed : 6277894  
Status : Reviewed

Primary-structure determination of fourteen neutral oligosaccharides derived from bronchial-mucus glycoproteins of patients suffering from cystic fibrosis, employing 500-MHz 1H-NMR spectroscopy. (1982)
van Halbeek H, Dorland L, Vliegenthart J, Hull W, Lamblin G, Lhermitte M, Boersma A, Roussel P
Pubmed : 7140761  
Status : Reviewed

Isolation and characterisation of neutral oligosaccharides from human bronchial glycoproteins. (1982)
Lamblin G, Lhermitte M, Boersma A, Roussel P, Van Halbeek H, Dorland L, Vliegenthart J
Pubmed : 7080930  
Status : Reviewed

The chemical structure of neutral and acidic sugar chains obtained from bovine colostrum kappa-casein. (1981)
Saito T, Itoh T, Adachi S, Suzuki T, Usui T
Pubmed : 7317452  
Status : Reviewed

Heterogeneity of the glycans O-glycosidically linked to the hinge region of secretory immunoglobulins from human milk. (1981)
Pierce-Cretel A, Pamblanco M, Strecker G, Montreuil J, Spik G
Pubmed : 7215351  
Status : Reviewed

Structure of the asialyl oligosaccharide chains of kappa-casein isolated from ovine colostrum. (1980)
Soulier S, Sarfati R, Szab L
Pubmed : 7408862  
Status : Reviewed

Immunochemical studies on blood groups. Structures and immunochemical properties of oligosaccharides from two fractions of blood group substance from human ovarian cyst fluid differing in B, I, and i activities and reactivity toward concanavalin A. (1976)
Maisonrouge-McAuliffe F, Kabat E
Pubmed : 952526  
Status : Reviewed

Structures of oligosaccharides produced by base--borohydride degradation of human ovarian cyst blood group H, Le-b and Le-a active glycoproteins. (1973)
Rovis L, Anderson B, Kabat E, Gruenzo F, Liao J
Pubmed : 4357339  
Status : Reviewed