Structure

Details for this Core 1 / O-Linked glycan structure

SNFG, Text, Oxford

    Mass spectrometry validated peptide

Glycan references

GlyTouCan : G01614ZM

UniCarb-DB :

Composition

Hex:1 HexNAc:1 NeuAc:2

IUPAC

NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
5s:n-acetyl
6b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
7s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:3o(3+2)4d
4:4d(5+1)5n
5:1o(6+2)6d
6:6d(5+1)7n


References (86)

The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis (2014)
Ali L, Flowers SA, Jin C, Bennet EP, Ekwall AK, Karlsson NG
Pubmed : 25187573   DOI : 10.1074/mcp.M114.040865
Status : Reviewed

Site-specific analysis of the O-glycosylation of bovine fetuin by electron-transfer dissociation mass spectrometry (2014)
Windwarder M, Altmann F
Pubmed : 24907489   DOI : 10.1016/j.jprot.2014.05.022
Status : Reviewed

Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans. (2003)
Dell A, Chalabi S, Easton RL, Haslam SM, Sutton-Smith M, Patankar MS, Lattanzio F, Panico M, Morris HR, Clark GF
Pubmed : 14673092   DOI : 10.1073/pnas.2635507100
Status : Reviewed

Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation. (2002)
Muller S, Hanisch FG
Pubmed : 12000758   DOI : 10.1074/jbc.M202921200
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Structural elucidation of the N- and O-glycans of human apolipoprotein(a): role of O-glycans in conferring protease resistance. (2001)
Garner B, Merry A, Royle L, Harvey D, Rudd P, Thillet J
Pubmed : 11294842   DOI : 10.1074/jbc.M102150200
Status : Reviewed

Glycosylation analysis of two cysteine proteinase inhibitors from Atlantic salmon skin: di-O-acetylated sialic acids are the major sialic acid species on N-glycans (2001)
Ylonen, Kalkkinen, Saarinen, Bogwald, Helin
Pubmed : 11447131  
Status : Reviewed

O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organization of the enzyme. (2000)
Mattu T, Royle L, Langridge J, Wormald M, Van den Steen P, Van Damme J, Opdenakker G, Harvey D, Dwek R, Rudd P
Pubmed : 11123894  
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Impaired galactosylation of core 2 O-glycans in erythrocytes of beta1,4-galactosyltransferase knockout mice. (1999)
Kotani N, Asano M, Iwakura Y, Takasaki S
Pubmed : 10381349   DOI : 10.1006/bbrc.1999.0872
Status : Reviewed

Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type" neutral N-glycans. (1999)
Zamze S, Harvey D, Pesheva P, Mattu T, Schachner M, Dwek R, Wing D
Pubmed : 10406848  
Status : Reviewed

High prevalence of 2-mono- and 2,6-di-substituted manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis. (1999)
Chai W, Yuen C, Kogelberg H, Carruthers R, Margolis R, Feizi T, Lawson A
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Status : Reviewed

Phosphorylation and O-glycosylation sites of human chromogranin A (CGA79-439) from urine of patients with carcinoid tumors. (1998)
Gadroy P, Stridsberg M, Capon C, Michalski J, Strub J, Van Dorsselaer A, Aunis D, Metz-Boutigue M
Pubmed : 9852066  
Status : Reviewed

Structural study of the O-linked sugar chains of human leukocyte tyrosine phosphatase CD45. (1998)
Furukawa K, Funakoshi Y, Autero M, Horejsi V, Kobata A, Gahmberg C
Pubmed : 9492296  
Status : Reviewed

Structural characterisation of N-linked and O-linked oligosaccharides derived from interferon-alpha2b and interferon-alpha14c produced by Sendai-virus-induced human peripheral blood leukocytes (1998)
Nyman, Kalkkinen, Tolo, Helin
Pubmed : 9654101  
Status : Reviewed

The glycosylation and structure of human serum IgA1, Fab, and Fc regions and the role of N-glycosylation on Fc alpha receptor interactions. (1998)
Mattu T, Pleass R, Willis A, Kilian M, Wormald M, Lellouch A, Rudd P, Woof J, Dwek R
Pubmed : 9442070  
Status : Reviewed

Structural determination of the O-linked sialyl oligosaccharides liberated from fetuin with endo-alpha-N-acetylgalactosaminidase-S by HPLC analysis and 600-MHz 1H-NMR spectroscopy. (1997)
Ishii-Karakasa I, Iwase H, Hotta K
Pubmed : 9266717  
Status : Reviewed

Structure of the O-linked oligosaccharides from a major thyroid cell surface glycoprotein. (1997)
Edge A, Spiro R
Pubmed : 9210648   DOI : 10.1006/abbi.1997.0143
Status : Reviewed

Glycosylation analysis and protein structure determination of murine fetal antigen 1 (mFA1)--the circulating gene product of the delta-like protein (dlk), preadipocyte factor 1 (Pref-1) and stromal-cell-derived protein 1 (SCP-1) cDNAs. (1997)
Krogh T, Bachmann E, Teisner B, Skjdt K, Hjrup P
Pubmed : 9118998  
Status : Reviewed

Peptide, disulfide, and glycosylation mapping of recombinant human thrombopoietin from ser1 to Arg246. (1996)
Hoffman RC, Andersen H, Walker K, Krakover JD, Patel S, Stamm MR, Osborn SG
Pubmed : 8942648   DOI : 10.1021/bi961075b
Status : Reviewed

Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells. (1996)
Lloyd KO, Burchell J, Kudryashov V, Yin BW, Taylor-Papadimitriou J
Pubmed : 8969192  
Status : Reviewed

Structural analysis of the sialylated N- and O-linked carbohydrate chains of recombinant human erythropoietin expressed in Chinese hamster ovary cells. Sialylation patterns and branch location of dimeric N-acetyllactosamine units. (1995)
Hokke C, Bergwerff A, Van Dedem G, Kamerling J, Vliegenthart J
Pubmed : 7737204  
Status : Reviewed

Sialylation and sulfation of the carbohydrate chains in respiratory mucins from a patient with cystic fibrosis. (1994)
Lo-Guidice J, Wieruszeski J, Lemoine J, Verbert A, Roussel P, Lamblin G
Pubmed : 8034632  
Status : Reviewed

Structure determination of the intact major sialylated oligosaccharide chains of recombinant human erythropoietin expressed in Chinese hamster ovary cells. (1994)
Watson E, Bhide A, van Halbeek H
Pubmed : 8054720  
Status : Reviewed

An improved approach to the analysis of the structure of small oligosaccharides of glycoproteins: application to the O-linked oligosaccharides from human glycophorin A. (1993)
Krotkiewski H, Lisowska E, Nilsson G, Grnberg G, Nilsson B
Pubmed : 8384526  
Status : Reviewed

Structures of mucin-type sugar chains on human erythropoietins purified from urine and the culture medium of recombinant Chinese hamster ovary cells. (1993)
Inoue N, Takeuchi M, Asano K, Shimizu R, Takasaki S, Kobata A
Pubmed : 8460945   DOI : 10.1006/abbi.1993.1158
Status : Reviewed

Structures of sialylated oligosaccharides of human erythropoietin expressed in recombinant BHK-21 cells. (1993)
Nimtz M, Martin W, Wray V, Klppel K, Augustin J, Conradt H
Pubmed : 8477709  
Status : Reviewed

The carbohydrate chains of the beta subunit of human chorionic gonadotropin produced by the choriocarcinoma cell line BeWo. Novel O-linked and novel bisecting-GlcNAc-containing N-linked carbohydrates. (1992)
Hard K, Damm J, Spruijt M, Bergwerff A, Kamerling J, Van Dedem G, Vliegenthart J
Pubmed : 1374031  
Status : Reviewed

1H and 13C-NMR assignments for sialylated oligosaccharide-alditols related to mucins. Study of thirteen components from hen ovomucin and swallow nest mucin. (1992)
Strecker G, Wieruszeski J, Cuvillier O, Michalski J, Montreuil J
Pubmed : 1576207  
Status : Reviewed

Oligosaccharide structures of mucins secreted by the human colonic cancer cell line CL.16E. (1992)
Capon C, Laboisse C, Wieruszeski J, Maoret J, Augeron C, Fournet B
Pubmed : 1527047  
Status : Reviewed

Analysis of glycoform of O-glycan from human myeloma immunoglobulin A1 by gas-phase hydrazinolysis following pyridylamination of oligosaccharides. (1992)
Iwase H, Ishii-Karakasa I, Fujii E, Hotta K, Hiki Y, Kobayashi Y
Pubmed : 1280920  
Status : Reviewed

O-linked oligosaccharides of glycophorins A and B in erythrocytes of two individuals with the Tn polyagglutinability syndrome. (1992)
Blumenfeld O, Lalezari P, Khorshidi M, Puglia K, Fukuda M
Pubmed : 1421410  
Status : Reviewed

Altered O-glycan synthesis in lymphocytes from patients with Wiskott-Aldrich syndrome. (1991)
Piller F, Le Deist F, Weinberg K, Parkman R, Fukuda M
Pubmed : 2033371  
Status : Reviewed

The effect of the carbohydrate moiety upon the size and conformation of human plasma galactoglycoprotein as judged by electron microscopy and circular dichroism. Structural studies of a glycoprotein after stepwise enzymic carbohydrate removal. (1991)
Watzlawick H, Walsh M, Ehrhard I, Slayter H, Haupt H, Schwick H, Jourdian G, Hase S, Schmid K, Brossmer R
Pubmed : 1872812  
Status : Reviewed

Structure determination of the major N- and O-linked carbohydrate chains of the beta subunit from equine chorionic gonadotropin. (1990)
Damm J, Hard K, Kamerling J, van Dedem G, Vliegenthart J
Pubmed : 2331995  
Status : Reviewed

Structures of acidic O-linked polylactosaminoglycans on human skim milk mucins. (1990)
Hanisch F, Peter-Katalinic J, Egge H, Dabrowski U, Uhlenbruck G
Pubmed : 2136351  
Status : Reviewed

Oligosaccharides at individual glycosylation sites in glycoprotein 71 of Friend murine leukemia virus. (1990)
Geyer R, Dabrowski J, Dabrowski U, Linder D, Schlter M, Schott H, Stirm S
Pubmed : 2298213  
Status : Reviewed

Primary structure of the major O-glycosidically linked carbohydrate unit of human von Willebrand factor. (1989)
Samor B, Michalski J, Mazurier C, Goudemand M, De Waard P, Vliegenthart J, Strecker G, Montreuil J
Pubmed : 2535488  
Status : Reviewed

Structures of O-glycosidically linked oligosaccharides isolated from human meconium glycoproteins. (1989)
Capon C, Leroy Y, Wieruszeski J, Ricart G, Strecker G, Montreuil J, Fournet B
Pubmed : 2731547  
Status : Reviewed

Expression of human interleukin-2 in recombinant baby hamster kidney, Ltk-, and Chinese hamster ovary cells. Structure of O-linked carbohydrate chains and their location within the polypeptide. (1989)
Conradt H, Nimtz M, Dittmar K, Lindenmaier W, Hoppe J, Hauser H
Pubmed : 2793860  
Status : Reviewed

O-linked oligosaccharides from human serum immunoglobulin A1. (1989)
Field M, Dwek R, Edge C, Rademacher T
Pubmed : 2628063  
Status : Reviewed

Isolation and structural characterization of sialic-acid-containing glycopeptides of the O-glycosidic type from the urine of two patients with an hereditary deficiency in alpha-N-acetylgalactosaminidase activity. (1989)
Linden H, Klein R, Egge H, Peter-Katalinic J, Dabrowski J, Schindler D
Pubmed : 2775488  
Status : Reviewed

Comparative study of the mucin-type sugar chains of human chorionic gonadotropin present in the urine of patients with trophoblastic diseases and healthy pregnant women. (1988)
Amano J, Nishimura R, Mochizuki M, Kobata A
Pubmed : 3335536  
Status : Reviewed

Structural analysis of O-glycosidic type of sialyloligosaccharide-alditols derived from urinary glycopeptides of a sialidosis patient. (1988)
van Pelt J, Van Bilsen D, Kamerling J, Vliegenthart J
Pubmed : 3371361  
Status : Reviewed

The N- and O-linked carbohydrate chains of human, bovine and porcine plasminogen. Species specificity in relation to sialylation and fucosylation patterns. (1988)
Marti T, Schaller J, Rickli E, Schmid K, Kamerling J, Gerwig G, van Halbeek H, Vliegenthart J
Pubmed : 3356193  
Status : Reviewed

Structural studies on oncofetal carbohydrate antigens (Ca 19-9, Ca 50, and Ca 125) carried by O-linked sialyloligosaccharides on human amniotic mucins. (1988)
Hanisch F, Uhlenbruck G, Peter-Katalinic J, Egge H
Pubmed : 3191509  
Status : Reviewed

Human T-lymphocyte activation is associated with changes in O-glycan biosynthesis. (1988)
Piller F, Piller V, Fox R, Fukuda M
Pubmed : 2971663  
Status : Reviewed

Structural analysis by fast-atom-bombardment mass spectrometry of the mixture of alditols derived from the O-linked oligosaccharides of murine glycophorins. (1988)
Krotkiewski H, Lisowska E, Angel A, Nilsson B
Pubmed : 3242812  
Status : Reviewed

Identification of a tetrasialylated monofucosylated tetraantennary N-linked carbohydrate chain in human platelet glycocalicin. (1988)
Korrel S, Clemetson K, van Halbeek H, Kamerling J, Sixma J, Vliegenthart J
Pubmed : 3342888  
Status : Reviewed

[Sialic acid containing compounds in the hemofiltrate of patients with chronic renal insufficiency. II. Isolation and structure determination of sialoglycopeptides] (1987)
Weisshaar G, Baumann W, Friebolin H, Brunner H, Mann H, Sieberth H, Opferkuch H
Pubmed : 3442598  
Status : Reviewed

The structures of N- and O-glycosidic carbohydrate chains of a chondroitin sulfate proteoglycan isolated from the media of the human aorta. (1987)
Akiyama F, Stevens R, Hayashi S, Swann D, Binette J, Caterson B, Schmid K, Van Halbeek H, Mutsaers J, Gerwig G
Pubmed : 3813552  
Status : Reviewed

Isolation of sialylcompounds from hemofiltrate of chronic uremic patients and identification by nuclear magnetic resonance. (1987)
Weisshaar G, Brunner H, Friebolin H, Baumann W, Mann H, Opferkuch H, Sieberth H
Pubmed : 3447438  
Status : Reviewed

Structures of novel sialylated O-linked oligosaccharides isolated from human erythrocyte glycophorins. (1987)
Fukuda M, Lauffenburger M, Sasaki H, Rogers ME, Dell A
Pubmed : 3624241  
Status : Reviewed

Membrane glycophorins of Dantu blood group erythrocytes. (1987)
Blumenfeld O, Smith A, Moulds J
Pubmed : 3305497  
Status : Reviewed

Structures of O-linked oligosaccharides isolated from normal granulocytes, chronic myelogenous leukemia cells, and acute myelogenous leukemia cells. (1986)
Fukuda M, Carlsson S, Klock J, Dell A
Pubmed : 3462190  
Status : Reviewed

Characterization of O-glycosidically linked oligosaccharides of rat erythrocyte membrane sialoglycoproteins. (1986)
Edge A, Van Langenhove A, Reinhold V, Weber P
Pubmed : 3801456  
Status : Reviewed

Structures of O-linked oligosaccharides present in the proteoglycans secreted by human mammary epithelial cells. (1986)
Gowda D, Bhavanandan V, Davidson E
Pubmed : 3007481  
Status : Reviewed

The structure of the O-glycosidic oligosaccharide chains of the major Zajdela hepatoma ascites-cell-membrane glycoprotein. (1986)
Nato F, Goulut C, Bourrillon R, Van Halbeek H, Vliegenthart J
Pubmed : 3758066  
Status : Reviewed

Structural variations of O-linked oligosaccharides present in leukosialin isolated from erythroid, myeloid, and T-lymphoid cell lines. (1986)
Carlsson S, Sasaki H, Fukuda M
Pubmed : 2943741  
Status : Reviewed

Membrane glycophorins in Sta blood group erythrocytes. (1986)
Blumenfeld O, Adamany A, Kikuchi M, Sabo B, McCreary J
Pubmed : 3514617  
Status : Reviewed

Structures of the major carbohydrates of natural human interleukin-2. (1985)
Conradt H, Geyer R, Hoppe J, Grotjahn L, Plessing A, Mohr H
Pubmed : 3935432  
Status : Reviewed

Comparative study of glycophorin A derived O-glycans from human Cad, Sd(a+) and Sd(a-) erythrocytes. (1985)
Blanchard D, Capon C, Leroy Y, Cartron J, Fournet B
Pubmed : 4091823  
Status : Reviewed

Structure determination of oligosaccharides isolated from Cad erythrocyte membranes by permethylation analysis and 500-MHz 1H-NMR spectroscopy. (1985)
Herkt F, Parente J, Leroy Y, Fournet B, Blanchard D, Cartron J, van Halbeek H, Vliegenthart J
Pubmed : 3967649  
Status : Reviewed

Structural studies of O-glycosidic oligosaccharide units of dog erythrocyte glycophorin. (1985)
Yamashita T, Murayama J, Utsumi H, Hamada A
DOI : 10.1016/0304-4165(85)90177-1
Status : Reviewed

The structure of sialyl-glycopeptides of the O-glycosidic type, isolated from sialidosis (mucolipidosis I) urine. (1984)
Lecat D, Lemonnier M, Derappe C, Lhermitte M, van Halbeek H, Dorland L, Vliegenthart J
Pubmed : 6714238  
Status : Reviewed

Purification and structures of oligosaccharide chains in swine trachea and Cowper's gland mucin glycoproteins. (1984)
Rana SS, Chandrasekaran EV, Kennedy J, Mendicino J
Pubmed : 6436240  
Status : Reviewed

The structure of the carbohydrate units of human plasma galactoglycoprotein determined by 500-megahertz 1H NMR spectroscopy. (1984)
Akiyama K, Simons E, Bernasconi P, Schmid K, van Halbeek H, Vliegenthart J, Haupt H, Schwick H
Pubmed : 6725284  
Status : Reviewed

Structural studies on the O-linked carbohydrate chains of human platelet glycocalicin. (1984)
Korrel S, Clemetson K, Van Halbeek H, Kamerling J, Sixma J, Vliegenthart J
Pubmed : 6327299  
Status : Reviewed

The carbohydrates of mouse hepatitis virus (MHV) A59: structures of the O-glycosidically linked oligosaccharides of glycoprotein E1. (1984)
Niemann H, Geyer R, Klenk H, Linder D, Stirm S, Wirth M
Pubmed : 6325180  
Status : Reviewed

Glycoprotein E1 of MHV-A59: structure of the O-linked carbohydrates and construction of full length recombinant cDNA clones. (1984)
Niemann H, Heisterberg-Moutsis G, Geyer R, Klenk H, Wirth M
Pubmed : 6331111  
Status : Reviewed

Study of the carbohydrate moiety of human serum sex hormone-binding globulin. (1983)
Avvakumov G, Matveentseva I, Akhrem L, Strel'chyonok O, Akhrem A
Pubmed : 6684483  
Status : Reviewed

Isolation and structural characterization of five major sialyloligosaccharides and a sialylglycopeptide from normal human urine. (1983)
Parkkinen J, Finne J
Pubmed : 6628386  
Status : Reviewed

Structures of the O-glycosidically linked oligosaccharides of human IgD. (1983)
Mellis S, Baenziger J
Pubmed : 6619128  
Status : Reviewed

Glycoproteins and proteoglycans of the chromaffin granule matrix. (1982)
Kiang W-L, Krusius T, Finne J, Margolis RU, Margolis RK
Pubmed : 7056734  
Status : Reviewed

Structures of N-linked and O-linked oligosaccharides on proteoglycan monomer isolated from the Swarm rat chondrosarcoma. (1982)
Nilsson B, De Luca S, Lohmander S, Hascall V
Pubmed : 7107637  
Status : Reviewed

The chemical structure of neutral and acidic sugar chains obtained from bovine colostrum kappa-casein. (1981)
Saito T, Itoh T, Adachi S, Suzuki T, Usui T
Pubmed : 7317452  
Status : Reviewed

Structural characterization of a novel acidic oligosaccharide unit derived from cow colostrum kappa-casein. A 500 MHz 1H-NMR study. (1981)
van Halbeek H, Dorland L, Vliegenthart J, Fiat A, Jolls P
Pubmed : 7308473  
Status : Reviewed

Structures of sialylated O-glycosidically and N-glycosidically linked oligosaccharides in a monoclonal immunoglobulin light chain. (1981)
Chandrasekaran EV, Mendicino A, Garver FA, Mendicino J
Pubmed : 6780550  
Status : Reviewed

Localization of the carbohydrate units in a human immunoglobulin light chain, protein Sm lambda. (1981)
Garver F, Chang L, Kiefer C, Mendicino J, Chandrasekaran E, Isobe T, Osserman E
Pubmed : 6786888  
Status : Reviewed

Amino acid and carbohydrate structural variants of glycoprotein products (M-N glycoproteins) of the M-N allelic locus. (1981)
Blumenfeld O, Adamany A, Puglia K
Pubmed : 6940143  
Status : Reviewed

Oligosaccharides on proteoglycans from the swarm rat chondrosarcoma. (1980)
Lohmander L, De Luca S, Nilsson B, Hascall V, Caputo C, Kimura J, Heinegard D
Pubmed : 7391006  
Status : Reviewed

A 360-MHz 1H-NMR study of three oligosaccharides isolated from cow kappa-casein. (1980)
van Halbeek H, Dorland L, Vliegenthart J, Fiat A, Jolles P
Pubmed : 7397215  
Status : Reviewed

The structures of the carbohydrate moieties of bovine blood coagulation factor X. (1980)
Mizuochi T, Yamashita K, Fujikawa K, Titani K, Kobata A
Pubmed : 6767721  
Status : Reviewed

Structure and location of the O-glycosidic carbohydrate units of human chorionic gonadotropin. (1979)
Kessler M, Mise T, Ghai R, Bahl O
Pubmed : 468798  
Status : Reviewed

Carbohydrate of the human plasminogen variants. III. Structure of the O-glycosidically linked oligosaccharide unit. (1979)
Hayes M, Castellino F
Pubmed : 479158  
Status : Reviewed

Cow kappa-casein: structure of the carbohydrate portion. (1979)
Fournet B, Fiat A, Alais C, Jolls P
Pubmed : 427192  
Status : Reviewed

Characterization of the oligosaccharide side chain of apolipoprotein C-III from human plasma very low density lipoproteins. (1978)
Vaith P, Assmann G, Uhlenbruck G
Pubmed : 208636  
Status : Reviewed

Structure of the O-glycosidically linked carbohydrate units of fetuin. (1974)
Spiro R, Bhoyroo V
Pubmed : 4137945  
Status : Reviewed

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