GlyConnect

taxonomy (5) protein (13) source (16) structure (1) composition (1) disease (9) reference (15) site (13) peptide (0)

Taxonomy

Protein

Source

Reported structure

O-Linked / Core 2 / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)[Gal(b1-3)]GalNAc

Composition

Hex:2 HexNAc:2 NeuAc:1 (avg mass : 1039.948 )

Disease

Reference

Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans. (2003 - Dell A, Chalabi S, Easton RL, Haslam SM, Sutton-Smith M, Patankar MS, Lattanzio F, Panico M, Morris HR, Clark GF) / Status : Reviewed
Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation. (2002 - Muller S, Hanisch FG) / Status : Reviewed
High prevalence of 2-mono- and 2,6-di-substituted manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis. (1999 - Chai W, Yuen C, Kogelberg H, Carruthers R, Margolis R, Feizi T, Lawson A) / Status : Reviewed
Structures of monosialyl oligosaccharides isolated from the respiratory mucins of a non-secretor (O, Lea+b-) patient suffering from chronic bronchitis. Characterization of a novel type of mucin carbohydrate core structure. (1994 - van Halbeek H, Strang A, Lhermitte M, Rahmoune H, Lamblin G, Roussel P) / Status : Reviewed
Sialylation and sulfation of the carbohydrate chains in respiratory mucins from a patient with cystic fibrosis. (1994 - Lo-Guidice J, Wieruszeski J, Lemoine J, Verbert A, Roussel P, Lamblin G) / Status : Reviewed
1H and 13C-NMR assignments for sialylated oligosaccharide-alditols related to mucins. Study of thirteen components from hen ovomucin and swallow nest mucin. (1992 - Strecker G, Wieruszeski J, Cuvillier O, Michalski J, Montreuil J) / Status : Reviewed
Oligosaccharide structures of mucins secreted by the human colonic cancer cell line CL.16E. (1992 - Capon C, Laboisse C, Wieruszeski J, Maoret J, Augeron C, Fournet B) / Status : Reviewed
Structure determination of the major N- and O-linked carbohydrate chains of the beta subunit from equine chorionic gonadotropin. (1990 - Damm J, Hard K, Kamerling J, van Dedem G, Vliegenthart J) / Status : Reviewed
Comparative study of the mucin-type sugar chains of human chorionic gonadotropin present in the urine of patients with trophoblastic diseases and healthy pregnant women. (1988 - Amano J, Nishimura R, Mochizuki M, Kobata A) / Status : Reviewed
Structure of sialyl-oligosaccharides isolated from bronchial mucus glycoproteins of patients (blood group O) suffering from cystic fibrosis. (1987 - Breg J, Van Halbeek H, Vliegenthart J, Lamblin G, Houvenaghel M, Roussel P) / Status : Reviewed
Structures of O-linked oligosaccharides isolated from normal granulocytes, chronic myelogenous leukemia cells, and acute myelogenous leukemia cells. (1986 - Fukuda M, Carlsson S, Klock J, Dell A) / Status : Reviewed
The structure of the O-glycosidic oligosaccharide chains of the major Zajdela hepatoma ascites-cell-membrane glycoprotein. (1986 - Nato F, Goulut C, Bourrillon R, Van Halbeek H, Vliegenthart J) / Status : Reviewed
Structural variations of O-linked oligosaccharides present in leukosialin isolated from erythroid, myeloid, and T-lymphoid cell lines. (1986 - Carlsson S, Sasaki H, Fukuda M) / Status : Reviewed
The carbohydrate moiety of human platelet glycocalicin. (1983 - Tsuji T, Tsunehisa S, Watanabe Y, Yamamoto K, Tohyama H, Osawa T) / Status : Reviewed
Structure of O-glycosidically linked sugar units from plasma membranes of an ascites hepatoma, AH 66. (1982 - Funakoshi I, Yamashina I) / Status : Reviewed

Reported glycosite

Choriogonadotropin - alpha and beta chains / Homo sapiens
- Undefined site
Glycocalicin / Homo sapiens
- Undefined site
Leukosialin (cd43) / Homo sapiens
- Undefined site
Muc1 fusion protein / Homo sapiens
- Undefined site
Mucin / Homo sapiens
- Undefined site
Uncharacterized protein from Granulocyte / Homo sapiens
- Undefined site
Uncharacterized protein from Granulocyte / Homo sapiens
- Undefined site
Zona pellucida sperm-binding protein 3 / Homo sapiens
- Undefined site
Choriogonadotropin beta chain / Equus caballus
- Undefined site
Brain non dialyzable glycopeptide / Oryctolagus cuniculus
- Undefined site
Major membrane glycoprotein - MII2 / Rattus norvegicus
- Undefined site
Uncharacterized protein from Cell Membranes / Rattus norvegicus
- Undefined site
Mucin / Collocalia sp
- Undefined site

Mass spectrometry observed peptide

- O-Linked / Core 2 (avg mass : 1039.948)

Cross-references

GlyTouCan : G11457RF

UniCarb-DB :

Composition

Hex:2 HexNAc:2 NeuAc:1

IUPAC

NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)[Gal(b1-3)]GalNAc

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:b-dglc-HEX-1:5
5s:n-acetyl
6b:b-dgal-HEX-1:5
7b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
8s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(6+1)4d
4:4d(2+1)5n
5:4o(4+1)6d
6:6o(3+2)7d
7:7d(5+1)8n