Structure

Glycan references

GlyTouCan : G58667NI

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Composition

Hex:4 HexNAc:4 dHex:1

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IUPAC

Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:b-dglc-HEX-1:5
4s:n-acetyl
5b:b-dman-HEX-1:5
6b:a-dman-HEX-1:5
7b:b-dglc-HEX-1:5
8s:n-acetyl
9b:b-dgal-HEX-1:5
10b:a-dman-HEX-1:5
11b:b-dglc-HEX-1:5
12s:n-acetyl
13b:a-lgal-HEX-1:5|6:d
LIN
1:1d(2+1)2n
2:1o(4+1)3d
3:3d(2+1)4n
4:3o(4+1)5d
5:5o(3+1)6d
6:6o(2+1)7d
7:7d(2+1)8n
8:7o(4+1)9d
9:5o(6+1)10d
10:10o(2+1)11d
11:11d(2+1)12n
12:1o(6+1)13d

References (26)

Structural studies on IgG oligosaccharides of patients with primary Sjogren's syndrome. (2002)
Kuroda Y, Nakata M, Makino A, Matsumoto A, Ohashi K, Itahashi K, Takeuchi F, Goto M, Kojima N, Mizuochi T
Pubmed : 12652077  
Status : Reviewed

In vivo trafficking and catabolism of IgG1 antibodies with Fc associated carbohydrates of differing structure. (2000)
Wright A, Sato Y, Okada T, Chang K, Endo T, Morrison S
Pubmed : 11159927  
Status : Reviewed

Oligosaccharide analysis and molecular modeling of soluble forms of glycoproteins belonging to the Ly-6, scavenger receptor, and immunoglobulin superfamilies expressed in Chinese hamster ovary cells. (1999)
Rudd P, Wormald M, Harvey D, Devasahayam M, McAlister M, Brown M, Davis S, Barclay A, Dwek R
Pubmed : 10207177  
Status : Reviewed

Localization of neutral N-linked carbohydrate chains in pig zona pellucida glycoprotein ZPC. (1999)
Yonezawa N, Fukui N, Kudo K, Nakano M
Pubmed : 10091584  
Status : Reviewed

N-glycan structures of a recombinant mouse soluble Fcgamma receptor II. (1998)
Takahashi N, Yamada W, Masuda K, Araki H, Tsukamoto Y, Galinha A, Sauts C, Kato K, Shimada I
Pubmed : 10052594  
Status : Reviewed

Multiple interactions of IgG with its core oligosaccharide can modulate recognition by complement and human Fc gamma recpetor I and influence the synthesis of its oligosaccharide chains (1996)
Lund, Takahashi, Pound, Goodall, Jefferis
Pubmed : 8943402  
Status : Reviewed

First evidence of human meconium glycoasparagines. (1995)
Cuvillier O, Alonso C, Wieruszeski J, Brassart C, Strecker G, Bouquelet S, Michalski J
Pubmed : 7655165  
Status : Reviewed

Identification of neutral and sialyl N-linked oligosaccharide structures from human serum glycoproteins using three kinds of high-performance liquid chromatography. (1995)
Nakagawa H, Kawamura Y, Kato K, Shimada I, Arata Y, Takahashi N
Pubmed : 7785764   DOI : 10.1006/abio.1995.1200
Status : Reviewed

Structural characterization of the N-glycans of a humanized anti-CD18 murine immunoglobulin G. (1994)
Ip C, Miller W, Silberklang M, Mark G, Ellis R, Huang L, Glushka J, Van Halbeek H, Zhu J, Alhadeff J
Pubmed : 7906504  
Status : Reviewed

Structural changes in the N-linked sugar chains of serum immunoglobulin G of HTLV-I transgenic mice. (1993)
Endo T, Iwakura Y, Kobata A
Pubmed : 8507175   DOI : 10.1006/bbrc.1993.1516
Status : Reviewed

Control of IgG/Fc glycosylation: a comparison of oligosaccharides from chimeric human/mouse and mouse subclass immunoglobulin Gs. (1993)
Lund J, Takahashi N, Nakagawa H, Goodall M, Bentley T, Hindley S, Tyler R, Jefferis R
Pubmed : 8502242  
Status : Reviewed

Characterization of E-PHA-reactive alpha-fetoprotein isoforms by two-dimensional lectin affinity electrophoresis. (1993)
Taketa K, Fujii Y, Taga H
Pubmed : 7511099  
Status : Reviewed

Structures of the asparagine-linked oligosaccharide chains of human von Willebrand factor. Occurrence of blood group A, B, and H(O) structures. (1992)
Matsui T, Titani K, Mizuochi T
Pubmed : 1577715  
Status : Reviewed

Detailed structural analysis of asparagine-linked oligosaccharides of the nicotinic acetylcholine receptor from Torpedo californica. (1992)
Shoji H, Takahashi N, Nomoto H, Ishikawa M, Shimada I, Arata Y, Hayashi K
Pubmed : 1633814  
Status : Reviewed

Structural analysis of the N-linked carbohydrate chains of the 55-kDa glycoprotein family (PZP3) from porcine zona pellucida. (1992)
Noguchi S, Hatanaka Y, Tobita T, Nakano M
Pubmed : 1551388  
Status : Reviewed

A simple method for the release of asparagine-linked oligosaccharides from a glycoprotein purified by SDS-polyacrylamide gel electrophoresis. (1992)
Kawashima H, Murata T, Yamamoto K, Tateishi A, Irimura T, Osawa T
Pubmed : 1639758  
Status : Reviewed

Structural study of the sugar moieties of monoclonal antibodies secreted by human-mouse hybridoma. (1991)
Tandai M, Endo T, Sasaki S, Masuho Y, Kochibe N, Kobata A
Pubmed : 1952948  
Status : Reviewed

Bovine glomerular basement membrane. Location and structure of the asparagine-linked oligosaccharide units and their potential role in the assembly of the 7 S collagen IV tetramer. (1991)
Langeveld J, Noelken M, Hrd K, Todd P, Vliegenthart J, Rouse J, Hudson B
Pubmed : 1990011  
Status : Reviewed

Neutral oligosaccharide structures linked to asparagines of porcine zona pellucida glycoproteins. (1991)
Mori E, Takasaki S, Hedrick J, Wardrip N, Mori T, Kobata A
Pubmed : 1998670  
Status : Reviewed

Carbohydrate structure of human pancreatic elastase 1. (1991)
Wendorf P, Linder D, Sziegoleit A, Geyer R
Pubmed : 1898343  
Status : Reviewed

A comparative study of the N-linked oligosaccharide structures of human IgG subclass proteins. (1990)
Jefferis R, Lund J, Mizutani H, Nakagawa H, Kawazoe Y, Arata Y, Takahashi N
Pubmed : 2363690  
Status : Reviewed

The polypeptide of immunoglobulin G influences its galactosylation in vivo. (1990)
Lee S, Connolly J, Ramirez-Soto D, Poretz R
Pubmed : 2108149  
Status : Reviewed

Structural heterogeneity of sugar chains in immunoglobulin G. Conformation of immunoglobulin G molecule and substrate specificities of glycosyltransferases. (1990)
Fujii S, Nishiura T, Nishikawa A, Miura R, Taniguchi N
Pubmed : 2138613  
Status : Reviewed

A protein structural change in aglycosylated IgG3 correlates with loss of huFc gamma R1 and huFc gamma R111 binding and/or activation. (1990)
Lund J, Tanaka T, Takahashi N, Sarmay G, Arata Y, Jefferis R
Pubmed : 2174119  
Status : Reviewed

Comparative structural study of the N-linked oligosaccharides of human normal and pathological immunoglobulin G. (1987)
Takahashi N, Ishii I, Ishihara H, Mori M, Tejima S, Jefferis R, Endo S, Arata Y
Pubmed : 3567160  
Status : Reviewed

Structures of the sugar chains of rabbit immunoglobulin G: occurrence of asparagine-linked sugar chains in Fab fragment. (1985)
Taniguchi T, Mizuochi T, Beale M, Dwek R, Rademacher T, Kobata A
Pubmed : 4074713  
Status : Reviewed