GlyConnect

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taxonomy (10) protein (18) source (22) structure (1) composition (1) disease (10) reference (26) site (18) peptide (0)

Taxonomy

Protein

Source

Reported structure

O-Linked / Core 0 / NeuAc(a2-6)GalNAc

Composition

HexNAc:1 NeuAc:1 (avg mass : 512.4682 )

Disease

Reference

The O-Glycome of Human Nigrostriatal Tissue and Its Alteration in Parkinson's Disease. (2021 - Wilkinson H, Thomsson KA, Rebelo AL, Hilliard M, Pandit A, Rudd PM, Karlsson NG, Saldova R.) / Status : Unreviewed
Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation. (2002 - Muller S, Hanisch FG) / Status : Reviewed
Neutralization of pH in the Golgi apparatus causes redistribution of glycosyltransferases and changes in the O-glycosylation of mucins. (2001 - Axelsson M, Karlsson N, Steel D, Ouwendijk J, Nilsson T, Hansson G) / Status : Reviewed
Structural analysis of 20 oligosaccharide-alditols released from the jelly coat of Rana palustris eggs by reductive beta-elimination characterization of the polymerized sequence [Gal(beta1, 3)GalNAc(alpha1-4)]n. (1999 - Maes E, Florea D, Coppin A, Strecker G) / Status : Reviewed
Purification and characterization of the MUC1 mucin-type glycoprotein, epitectin, from human urine: structures of the major oligosaccharide alditols. (1998 - Bhavanandan V, Zhu Q, Yamakami K, Dilulio N, Nair S, Capon C, Lemoine J, Fournet B) / Status : Reviewed
Structural studies on sialylated oligosaccharides of bonnet monkey (Macaca radiata) luteal phase cervical mucus glycoprotein. (1997 - Mahmood Z, Khan A, Kasi M, Kehmood K, Khan A, Hoessli D, Rungger-Braendle E, Jeanloz R, Nasir-Ud-Din) / Status : Reviewed
Structural characterization of the carbohydrate chains from the skin mucus sialoglycoprotein of the stingray Dasyatis akajei. (1997 - Sumi T, Hama Y, Maruyama D, Asakawa M, Nakagawa H) / Status : Reviewed
Purification and characterization of glycoprotein from the skin mucus of the rainbow trout, Salmo gairdneri. (1997 - Sumi T, Hama Y, Maruyama D, Asakawa M, Nakagawa H) / Status : Reviewed
The glycosylation of rat intestinal Muc2 mucin varies between rat strains and the small and large intestine. A study of O-linked oligosaccharides by a mass spectrometric approach. (1997 - Karlsson N, Herrmann A, Karlsson H, Johansson M, Carlstedt I, Hansson G) / Status : Reviewed
Structures of monosialyl oligosaccharides isolated from the respiratory mucins of a non-secretor (O, Lea+b-) patient suffering from chronic bronchitis. Characterization of a novel type of mucin carbohydrate core structure. (1994 - van Halbeek H, Strang A, Lhermitte M, Rahmoune H, Lamblin G, Roussel P) / Status : Reviewed
Structures of mucin-type sugar chains on human erythropoietins purified from urine and the culture medium of recombinant Chinese hamster ovary cells. (1993 - Inoue N, Takeuchi M, Asano K, Shimizu R, Takasaki S, Kobata A) / Status : Reviewed
The broad diversity of neutral and sialylated oligosaccharides derived from human salivary mucins. (1992 - Klein A, Carnoy C, Wieruszeski J, Strecker G, Strang A, van Halbeek H, Roussel P, Lamblin G) / Status : Reviewed
O-linked oligosaccharides of glycophorins A and B in erythrocytes of two individuals with the Tn polyagglutinability syndrome. (1992 - Blumenfeld O, Lalezari P, Khorshidi M, Puglia K, Fukuda M) / Status : Reviewed
Analysis of N- and O-glycosidically bound sialooligosaccharides in glycoproteins by high-performance liquid chromatography with pulsed amperometric detection. (1990 - Honda S, Suzuki S, Zaiki S, Kakehi K) / Status : Reviewed
Isolation and structural characterization of low-molecular-mass monosialyl oligosaccharides derived from respiratory-mucus glycoproteins of a patient suffering from bronchiectasis. (1988 - van Halbeek H, Breg J, Vliegenthart J, Klein A, Lamblin G, Roussel P) / Status : Reviewed
Structure of acidic oligosaccharides isolated from pronase-treated glycoprotein of bonnet-monkey (Macaca radiata) cervical mucus. (1987 - Nasir-ud-Din ) / Status : Reviewed
Structures of novel sialylated O-linked oligosaccharides isolated from human erythrocyte glycophorins. (1987 - Fukuda M, Lauffenburger M, Sasaki H, Rogers ME, Dell A) / Status : Reviewed
Structure of sialyloligosaccharides isolated from bonnet monkey (Macaca radiata) cervical mucus glycoproteins exhibiting multiple blood group activities. (1986 - Nasir-Ud-Din , Jeanloz R, Lamblin G, Roussel P, van Halbeek H, Mutsaers J, Vliegenthart J) / Status : Reviewed
Carbohydrate structures of bovine submaxillary mucin. (1986 - Tsuji T, Osawa T) / Status : Reviewed
Structural variations of O-linked oligosaccharides present in leukosialin isolated from erythroid, myeloid, and T-lymphoid cell lines. (1986 - Carlsson S, Sasaki H, Fukuda M) / Status : Reviewed
Oligosaccharide structures of isolated human colonic mucin species. (1985 - Podolsky D) / Status : Reviewed
Oligosaccharide structures of human colonic mucin. (1985 - Podolsky D) / Status : Reviewed
Purification and structures of oligosaccharide chains in swine trachea and Cowper's gland mucin glycoproteins. (1984 - Rana SS, Chandrasekaran EV, Kennedy J, Mendicino J) / Status : Reviewed
Structure of disaccharide from eel skin mucous glycoprotein and its linkage to protein moiety. (1983 - Asakawa M) / Status : Reviewed
Structures of the major oligosaccharides from a human rectal adenocarcinoma glycoprotein. (1983 - Kurosaka A, Nakajima H, Funakoshi I, Matsuyama M, Nagayo T, Yamashina I) / Status : Reviewed
Isolation and characterization of oligosaccharides from canine submaxillary mucin. (1974 - Lombart C, Winzler R) / Status : Reviewed

Reported glycosite

Erythropoietin / Homo sapiens
- Undefined site
Glycophorin a and b / Homo sapiens
- Undefined site
Glycophorin a, b and c / Homo sapiens
- Undefined site
Leukosialin (cd43) / Homo sapiens
- Undefined site
Muc1 fusion protein / Homo sapiens
- Undefined site
Mucin-1 / Homo sapiens
- Undefined site
Mucin-2 / Homo sapiens
- Undefined site
Rgm / Homo sapiens
- Undefined site
Unspecified mucin / Homo sapiens
- Undefined site
Mucin / Bos taurus
- Undefined site
Mucin / Canis lupus familiaris
- Undefined site
Mucin / Macaca radiata
- Undefined site
Mucin-2 glycopeptide a / Rattus norvegicus
- Undefined site
Mucin / Sus scrofa
- Undefined site
Sialoglycoprotein / Anguilla japonica
- Undefined site
Mucus glycoprotein (rgp) / Oncorhynchus mykiss
- Undefined site
Mucin / Rana palustris
- Undefined site
Sialoglycoprotein / Dasyatis akajei
- Undefined site

Mass spectrometry observed peptide

- O-Linked / Core 0 (avg mass : 512.4682)

3D structure from GLYCAM

Cross-references

GlyTouCan : G36123IU

GlyGen : G36123IU

ChEBI : 61818

UniCarb-DB :

Composition

HexNAc:1 NeuAc:1

IUPAC

NeuAc(a2-6)GalNAc

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(6+2)3d
3:3d(5+1)4n

GWS

freeEnd--?a1D-GalNAc,p--6a2D-NeuAc,p$MONO,Und,0,0,freeEnd

SMILES

CC(=O)N[C@@H]1[C@H](C[C@@](O[C@H]1[C@@H]([C@@H](CO)O)O)(C(=O)O)OC[C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)O)NC(=O)C)O)O)O

InCHI key

CZOGCRVBCLRHQJ-WHWAGLCYSA-N

InCHI

InChI=1S/C19H32N2O14/c1-6(23)20-11-8(25)3-19(18(31)32,35-16(11)13(27)9(26)4-22)33-5-10-14(28)15(29)12(17(30)34-10)21-7(2)24/h8-17,22,25-30H,3-5H2,1-2H3,(H,20,23)(H,21,24)(H,31,32)/t8-,9+,10+,11+,12+,13+,14-,15+,16+,17-,19+/m0/s1