GlyConnect

taxonomy (8) protein (42) source (13) structure (1) composition (1) disease (4) reference (47) site (49) peptide (0)

Taxonomy

Protein

Source

Reported structure

N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )

Disease

Reference

N-Glycan structures of an osteopontin from human bone. (2000 - Masuda K, Takahashi N, Tsukamoto Y, Honma H, Kohri K) / Status : Reviewed
N-Glycan structures of an osteopontin from human bone. (2000 - Masuda K, Takahashi N, Tsukamoto Y, Honma H, Kohri K) / Status : Reviewed
Two-dimensional chromatography in the analysis of complex glycans from transferrin. (1998 - Charlwood J, Birrell H, Tolson D, Camilleri P) / Status : Reviewed
Expression of N-linked sialyl Le(x) determinants and O-glycans in the carbohydrate moiety of human amniotic fluid transferrin during pregnancy. (1998 - van Rooijen J, Jeschke U, Kamerling J, Vliegenthart J) / Status : Reviewed
Detailed oligosaccharide structures of human integrin alpha 5 beta 1 analyzed by a three-dimensional mapping technique. (1996 - Nakagawa H, Zheng M, Hakomori S, Tsukamoto Y, Kawamura Y, Takahashi N) / Status : Reviewed
Human alpha-fetoprotein produced from Hep G2 cell line: structure and heterogeneity of the oligosaccharide moiety. (1995 - Ferranti P, Pucci P, Marino G, Fiume I, Terrana B, Ceccarini C, Malorni A) / Status : Reviewed
Three-dimensional elution mapping of pyridylaminated N-linked neutral and sialyl oligosaccharides. (1995 - Takahashi N, Nakagawa H, Fujikawa K, Kawamura Y, Tomiya N) / Status : Reviewed
Structures of the N-linked oligosaccharides on human plasma vitronectin. (1995 - Ogawa H, Yoneda A, Seno N, Hayashi M, Ishizuka I, Hase S, Matsumoto I) / Status : Reviewed
Identification of neutral and sialyl N-linked oligosaccharide structures from human serum glycoproteins using three kinds of high-performance liquid chromatography. (1995 - Nakagawa H, Kawamura Y, Kato K, Shimada I, Arata Y, Takahashi N) / Status : Reviewed
An efficient preparation and structural characterization of sialylglycopeptides from protease treated egg yolk. (1995 - Koketsu M, Seko A, Juneja L, Kim M, Kashimura N, Yamamoto T) / Status : Reviewed
A strategy for the mapping of N-glycans by high-performance capillary electrophoresis. (1994 - Hermentin P, Doenges R, Witzel R, Hokke C, Vliegenthart J, Kamerling J, Conradt H, Nimtz M, Brazel D) / Status : Reviewed
Change in glycosylation of chicken transferrin glycans biosynthesized during embryogenesis and primary culture of embryo hepatocytes. (1994 - Jacquinot P, Leger D, Wieruszeski J, Coddeville B, Montreuil J, Spik G) / Status : Reviewed
Primary structure of the major glycan from human seminal transferrin. (1994 - D'Andrea G, D'Alessandro A, Salucci M, Oratore A) / Status : Reviewed
Human serum amyloid P component is an invariant constituent of amyloid deposits and has a uniquely homogeneous glycostructure. (1994 - Pepys M, Rademacher T, Amatayakul-Chantler S, Williams P, Noble G, Hutchinson W, Hawkins P, Nelson S, Gallimore J, Herbert J) / Status : Reviewed
Characterization of E-PHA-reactive alpha-fetoprotein isoforms by two-dimensional lectin affinity electrophoresis. (1993 - Taketa K, Fujii Y, Taga H) / Status : Reviewed
Sugar chains of human cord serum alpha-fetoprotein: characteristics of N-linked sugar chains of glycoproteins produced in human liver and hepatocellular carcinomas. (1993 - Yamashita K, Taketa K, Nishi S, Fukushima K, Ohkura T) / Status : Reviewed
Studies on the carbohydrate moiety and on the biosynthesis of rat C-reactive protein. (1993 - Sambasivam H, Rassouli M, Murray R, Nagpurkar A, Mookerjea S, Azadi P, Dell A, Morris H) / Status : Reviewed
Structures of sugar chains of hen egg yolk riboflavin-binding protein. (1993 - Tarutani M, Norioka N, Mega T, Hase S, Ikenaka T) / Status : Reviewed
Structures of the N-linked oligosaccharides on porcine plasma vitronectin. (1993 - Yoneda A, Ogawa H, Matsumoto I, Ishizuka I, Hase S, Seno N) / Status : Reviewed
Electrophoretic resolution and fluorescence detection of N-linked glycoprotein oligosaccharides after reductive amination with 8-aminonaphthalene-1,3,6-trisulphonic acid. (1992 - Stack R, Sullivan M) / Status : Reviewed
Structure of the N- and O-glycans of the A-chain of human plasma alpha 2HS-glycoprotein as deduced from the chemical compositions of the derivatives prepared by stepwise degradation with exoglycosidases. (1992 - Watzlawick H, Walsh M, Yoshioka Y, Schmid K, Brossmer R) / Status : Reviewed
Separation and characterization of the two Asn-linked glycosylation sites of chicken serum riboflavin-binding protein. Glycosylation differences despite similarity of primary structure. (1992 - Rohrer J, White H) / Status : Reviewed
N-glycosylation site mapping of human serotransferrin by serial lectin affinity chromatography, fast atom bombardment-mass spectrometry, and 1H nuclear magnetic resonance spectroscopy. (1992 - Fu D, van Halbeek H) / Status : Reviewed
Comparative study of asparagine-linked glycans of plasma T-kininogen in normal rats and during acute inflammation. (1992 - Baussant T, Alonso C, Wieruszeski J, Strecker G, Montreuil J, Alhenc-Gelas F, Michalski J) / Status : Reviewed
Structure determination of the glycans of human-serum alpha 1-antichymotrypsin using 1H-NMR spectroscopy and deglycosylation by N-glycanase. (1991 - Laine A, Hachulla E, Strecker G, Michalski J, Wieruszeski J) / Status : Reviewed
NMR investigations of the N-linked oligosaccharides at individual glycosylation sites of human lutropin. (1991 - Weisshaar G, Hiyama J, Renwick A, Nimtz M) / Status : Reviewed
Oligosaccharide structures present on asparagine-289 of recombinant human plasminogen expressed in a Chinese hamster ovary cell line. (1991 - Davidson D, Castellino F) / Status : Reviewed
Structures of the asparagine-289-linked oligosaccharides assembled on recombinant human plasminogen expressed in a Mamestra brassicae cell line (IZD-MBO503). (1991 - Davidson D, Castellino F) / Status : Reviewed
Asparagine-linked oligosaccharide processing in lepidopteran insect cells. Temporal dependence of the nature of the oligosaccharides assembled on asparagine-289 of recombinant human plasminogen produced in baculovirus vector infected Spodoptera frugiperda (IPLB-SF-21AE) cells. (1991 - Davidson D, Castellino F) / Status : Reviewed
Carbohydrate microheterogeneity of rat serotransferrin. Determination of glycan primary structures and characterization of a new type of trisialylated diantennary glycan. (1991 - Spik G, Coddeville B, Strecker G, Montreuil J, Regoeczi E, Chindemi P, Rudolph J) / Status : Reviewed
Structure determination of the major N- and O-linked carbohydrate chains of the beta subunit from equine chorionic gonadotropin. (1990 - Damm J, Hard K, Kamerling J, van Dedem G, Vliegenthart J) / Status : Reviewed
Structures of the asparagine-linked oligosaccharides of guinea-pig factor B of the alternative complement pathway. (1990 - Mizuochi T, Hamako J, Titani K, Matsushita M, Okada H) / Status : Reviewed
Primary structure of glycans isolated from human leucocyte lactotransferrin. Absence of fucose residues questions the proposed mechanism of hyposideraemia. (1990 - Derisbourg P, Wieruszeski J, Montreuil J, Spik G) / Status : Reviewed
The carbohydrate structures of a mouse monoclonal IgG antibody OKT3. (1990 - Krotkiewski H, Grnberg G, Krotkiewska B, Nilsson B, Svensson S) / Status : Reviewed
Oligosaccharide processing in the expression of human plasminogen cDNA by lepidopteran insect (Spodoptera frugiperda) cells. (1990 - Davidson D, Fraser M, Castellino F) / Status : Reviewed
The asparagine-linked oligosaccharides on bovine fetuin. Structural analysis of N-glycanase-released oligosaccharides by 500-megahertz 1H NMR spectroscopy. (1988 - Green E, Adelt G, Baenziger J, Wilson S, Van Halbeek H) / Status : Reviewed
The N- and O-linked carbohydrate chains of human, bovine and porcine plasminogen. Species specificity in relation to sialylation and fucosylation patterns. (1988 - Marti T, Schaller J, Rickli E, Schmid K, Kamerling J, Gerwig G, van Halbeek H, Vliegenthart J) / Status : Reviewed
The structures of the carbohydrate moieties of bovine blood coagulation factor IX (Christmas factor). (1983 - Mizuochi T, Taniguchi T, Fujikawa K, Titani K, Kobata A) / Status : Reviewed
Study of the carbohydrate moiety of human serum sex hormone-binding globulin. (1983 - Avvakumov G, Matveentseva I, Akhrem L, Strel'chyonok O, Akhrem A) / Status : Reviewed
The structures and microheterogeneity of the carbohydrate chains of human plasma ceruloplasmin. A study employing 500-MHz 1H-NMR spectroscopy. (1982 - Endo M, Suzuki K, Schmid K, Fournet B, Karamanos Y, Montreuil J, Dorland L, van Halbeek H, Vliegenthart J) / Status : Reviewed
Carbohydrate structure of human fibrinogen. Use of 300-MHz 1H-NMR to characterize glycosidase-treated glycopeptides. (1982 - Townsend RR, Hilliker E, Li Y-T, Laine RA, Bell WR, Lee YC) / Status : Reviewed
Structural studies of asparagine-linked sugar chains of human ceruloplasmin. Structural characteristics of the triantennary complex type sugar chains of human plasma glycoproteins. (1981 - Yamashita K, Liang CJ, Funakoshi S, Kobata A) / Status : Reviewed
Studies on the structures of the carbohydrate moiety of human prothrombin. (1981 - Mizuochi T, Fujii J, Kisiel W, Kobata A) / Status : Reviewed
Studies on the oligosaccharide chains of human alpha 1-protease inhibitor. II. Structure of oligosaccharides. (1980 - Mega T, Lujan E, Yoshida A) / Status : Reviewed
Structural studies of the sugar chains of cold-insoluble globulin isolated from human plasma. (1980 - Takasaki S, Yamashita K, Suzuki K, Kobata A) / Status : Reviewed
Structure of the oligosaccharide of human J chain. (1979 - Baenziger J) / Status : Reviewed
The carbohydrate of bovine prothrombin. Occurrence of Galb1-3GlcNAc grouping in asparagine-linked sugar chains. (1979 - Mizuochi T, Yamashita K, Fujikawa K, Kisiel W, Kobata A) / Status : Reviewed

Reported glycosite

Alpha-1-antichymotrypsin / Homo sapiens
- Undefined site
Alpha-1-antitrypsin / Homo sapiens
- Undefined site
Alpha-2-HS-glycoprotein / Homo sapiens
- Asn-156
- Asn-176
Alpha-fetoprotein / Homo sapiens
- Undefined site
- Asn-251
Ceruloplasmin / Homo sapiens
- Undefined site
Fibrinogen / Homo sapiens
- Undefined site
Fibrinogen beta chain / Homo sapiens
- Undefined site
Fibrinogen gamma chain / Homo sapiens
- Undefined site
Fibronectin / Homo sapiens
- Undefined site
Glycoprotein hormones alpha chain - choriogonadotropin / Homo sapiens
- Asn-76
- Asn-102
Immunoglobulin gamma / Homo sapiens
- Undefined site
Immunoglobulin j chain / Homo sapiens
- Asn-71
Integrin alpha-5/beta-1 / Homo sapiens
- Undefined site
Lactotransferrin / Homo sapiens
- Undefined site
Lutropin beta chain / Homo sapiens
- Asn-50
Osteopontin / Homo sapiens
- Undefined site
Plasminogen / Homo sapiens
- Asn-308
Prothrombin / Homo sapiens
- Undefined site
Recombinant plasminogen - [r580e] / Homo sapiens
- Undefined site
Recombinant plasminogen - [r580s] / Homo sapiens
- Undefined site
Seminal transferrin / Homo sapiens
- Undefined site
Serotransferrin / Homo sapiens
- Undefined site
- Asn-432
- Asn-630
Serum amyloid p-component / Homo sapiens
- Asn-51
Sex hormone-binding globulin / Homo sapiens
- Undefined site
Uncharacterized protein from Serum / Homo sapiens
- Undefined site
Vitronectin / Homo sapiens
- Undefined site
Alpha-2-hs-glycoprotein / Bos taurus
- Undefined site
Coagulation factor IX / Bos taurus
- Undefined site
Plasminogen / Bos taurus
- Asn-315
Prothrombin / Bos taurus
- Undefined site
Factor b1 / Cavia porcellus
- Undefined site
Factor b2 / Cavia porcellus
- Undefined site
Choriogonadotropin beta chain / Equus caballus
- Undefined site
Monoclonal antibody okt3 / Mus musculus
- Undefined site
C-reactive protein / Rattus norvegicus
- Asn-147
Serotransferrin / Rattus norvegicus
- Undefined site
T-kininogen / Rattus norvegicus
- Undefined site
Plasminogen / Sus scrofa
- Asn-289
Vitronectin / Sus scrofa
- Undefined site
Ovotransferrin / Gallus gallus
- Undefined site
Riboflavin-binding protein / Gallus gallus
- Undefined site
- Asn-53
- Asn-164
Uncharacterized protein from Yolk / Gallus gallus
- Undefined site

Mass spectrometry observed peptide

- N-Linked / Complex (avg mass : 2224.0231)

Cross-references

GlyTouCan : G84467IZ

UniCarb-DB :

Composition

Hex:5 HexNAc:4 NeuAc:2

IUPAC

NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc

GlycoCT

RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:b-dglc-HEX-1:5
4s:n-acetyl
5b:b-dman-HEX-1:5
6b:a-dman-HEX-1:5
7b:b-dglc-HEX-1:5
8s:n-acetyl
9b:b-dgal-HEX-1:5
10b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
11s:n-acetyl
12b:a-dman-HEX-1:5
13b:b-dglc-HEX-1:5
14s:n-acetyl
15b:b-dgal-HEX-1:5
16b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
17s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(4+1)3d
3:3d(2+1)4n
4:3o(4+1)5d
5:5o(3+1)6d
6:6o(2+1)7d
7:7d(2+1)8n
8:7o(4+1)9d
9:9o(6+2)10d
10:10d(5+1)11n
11:5o(6+1)12d
12:12o(2+1)13d
13:13d(2+1)14n
14:13o(4+1)15d
15:15o(6+2)16d
16:16d(5+1)17n