Comprehensive N- and O-glycosylation mapping of human coagulation factor V. (2020)
Ma C, Liu D, Li D, Zhang J, Xu XQ, Zhu H, Wan XF, Miao CH, Konkle BA, Onigman P, Xiao W, Li L
J Thromb Haemost, 2020 vol.18(8):1884-1892
SNFG,
Text,
Oxford
taxonomy (1)
protein (1)
source (1)
structure (56)
composition (54)
disease (0)
reference (1)
site (38)
peptide (0)
- Homo sapiens (Human)
Taxonomy
- Blood Plasma (UBERON_0001969)
Source
- N-Linked / Complex / Structure 1994
- N-Linked / Complex / Structure 11163
- N-Linked / Complex / Structure 11212
- N-Linked / Complex / Structure 11150
- N-Linked / Complex / Structure 11195
- N-Linked / Complex / Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
- N-Linked / Complex / Structure 9792
- N-Linked / Complex / Structure 11155
- N-Linked / Complex / Structure 9689
- N-Linked / Complex / Structure 11145
- N-Linked / Complex / Structure 11153
- N-Linked / Complex / Structure 11191
- N-Linked / Complex / Structure 11182
- N-Linked / Complex / Structure 11244
- N-Linked / Complex / Structure 11238
- N-Linked / Complex / Structure 11214
- N-Linked / Complex / Structure 11220
- N-Linked / Complex / Structure 11177
- N-Linked / Complex / Structure 11157
- N-Linked / Complex / NeuAc(a2-?)Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[NeuAc(a2-?)Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
- N-Linked / Complex / Structure 11127
- N-Linked / Complex / NeuAc(a2-?)Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[NeuAc(a2-?)Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
- N-Linked / Complex / Structure 11208
- N-Linked / Complex / Structure 11241
- N-Linked / Complex / Structure 11203
- N-Linked / Complex / Structure 11221
- N-Linked / Complex / Structure 11151
- N-Linked / Complex / Structure 11193
- N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man(b1-4)GlcNAc(b1-4)GlcNAc
- N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
- N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)GlcNAc
- N-Linked / High-Mannose / Structure 11236
- N-Linked / High-Mannose / Structure 11130
- N-Linked / Hybrid / Structure 9730
- N-Linked / Hybrid / Structure 10699
- N-Linked / Hybrid / Structure 11166
- N-Linked / Hybrid / Structure 11159
- N-Linked / Hybrid / Structure 11172
- N-Linked / Hybrid / Structure 11184
- O-Linked / Core 0 / GalNAc
- O-Linked / Core 1 / Gal(b1-3)GalNAc
- O-Linked / Core 1 / NeuAc(a2-?)Gal(b1-3)GalNAc
- O-Linked / Core 1 / Structure 11170
- O-Linked / Core 1 / Structure 10127
- O-Linked / Core 2 / Gal(b1-3)[GlcNAc(b1-6)]GalNAc
- O-Linked / Core 2 / Structure 10074
- O-Linked / Core 2 / Structure 11209
- O-Linked / Core 2 / Structure 11239
- O-Linked / Core 2 / Structure 11229
- O-Linked / Core 2 / Structure 11216
- O-Linked / Core 2 / Structure 11161
- O-Linked / Core 2 / Structure 11185
- O-Linked / Core 4 / Structure 11222
- O-Linked / Core 4 / Structure 11256
- O-Linked / Core 6 / Structure 11106
- O-Linked / Core 9 / Structure 11137
Reported structure
- HexNAc:1 (avg mass : 221.2103 )
- Hex:1 HexNAc:1 (avg mass : 383.3527 )
- Hex:1 HexNAc:1 NeuAc:1 (avg mass : 674.6106 )
- Hex:1 HexNAc:1 NeuAc:2 (avg mass : 965.8685 )
- Hex:1 HexNAc:2 (avg mass : 586.5477 )
- Hex:1 HexNAc:2 NeuAc:1 (avg mass : 877.8056 )
- Hex:1 HexNAc:2 dHex:1 NeuAc:1 (avg mass : 1023.9486 )
- Hex:2 HexNAc:1 NeuAc:1 (avg mass : 836.753 )
- Hex:2 HexNAc:2 (avg mass : 748.6901 )
- Hex:2 HexNAc:2 NeuAc:1 (avg mass : 1039.948 )
- Hex:2 HexNAc:2 NeuAc:2 (avg mass : 1331.2059 )
- Hex:2 HexNAc:2 dHex:1 NeuAc:1 (avg mass : 1186.091 )
- Hex:2 HexNAc:3 NeuAc:1 (avg mass : 1243.143 )
- Hex:2 HexNAc:3 NeuAc:2 (avg mass : 1534.4009 )
- Hex:3 HexNAc:3 NeuAc:2 (avg mass : 1696.5433 )
- Hex:3 HexNAc:3 dHex:1 NeuAc:2 (avg mass : 1842.6863 )
- Hex:3 HexNAc:4 Ph:1 (avg mass : 1397.2024 )
- Hex:3 HexNAc:5 dHex:1 (avg mass : 1666.5605 )
- Hex:3 HexNAc:6 dHex:1 (avg mass : 1869.7555 )
- Hex:4 HexNAc:3 (avg mass : 1276.1699 )
- Hex:4 HexNAc:3 NeuAc:1 (avg mass : 1567.4278 )
- Hex:4 HexNAc:3 dHex:1 (avg mass : 1422.3129 )
- Hex:4 HexNAc:3 dHex:2 (avg mass : 1568.4559 )
- Hex:4 HexNAc:4 NeuAc:1 (avg mass : 1770.6228 )
- Hex:4 HexNAc:5 dHex:1 (avg mass : 1828.7029 )
- Hex:4 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2119.9608 )
- Hex:4 HexNAc:5 dHex:2 (avg mass : 1974.8459 )
- Hex:4 HexNAc:6 NeuAc:1 (avg mass : 2177.0128 )
- Hex:5 HexNAc:2 (avg mass : 1235.1173 )
- Hex:5 HexNAc:2 dHex:1 (avg mass : 1381.2603 )
- Hex:5 HexNAc:3 NeuAc:1 (avg mass : 1729.5702 )
- Hex:5 HexNAc:3 dHex:1 (avg mass : 1584.4553 )
- Hex:5 HexNAc:3 dHex:1 NeuAc:1 (avg mass : 1875.7132 )
- Hex:5 HexNAc:4 (avg mass : 1641.5073 )
- Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )
- Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )
- Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )
- Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )
- Hex:5 HexNAc:4 dHex:2 NeuAc:2 (avg mass : 2516.3091 )
- Hex:5 HexNAc:4 dHex:3 (avg mass : 2079.9363 )
- Hex:5 HexNAc:5 NeuAc:1 (avg mass : 2135.9602 )
- Hex:5 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2573.3611 )
- Hex:5 HexNAc:6 NeuAc:1 (avg mass : 2339.1552 )
- Hex:6 HexNAc:2 (avg mass : 1397.2597 )
- Hex:6 HexNAc:2 dHex:1 (avg mass : 1543.4027 )
- Hex:6 HexNAc:3 (avg mass : 1600.4547 )
- Hex:6 HexNAc:3 NeuAc:1 (avg mass : 1891.7126 )
- Hex:6 HexNAc:3 dHex:1 (avg mass : 1746.5977 )
- Hex:6 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2444.2456 )
- Hex:6 HexNAc:6 (avg mass : 2210.0397 )
- Hex:7 HexNAc:2 (avg mass : 1559.4021 )
- Hex:7 HexNAc:6 NeuAc:1 (avg mass : 2663.44 )
- Hex:7 HexNAc:6 NeuAc:2 (avg mass : 2954.6979 )
- Hex:7 HexNAc:7 (avg mass : 2575.3771 )
Composition
Disease
-
Coagulation factor V / Homo sapiens
- Asn-297
- Ser-310
- Asn-382
- Asn-468
- Asn-554
- Ser-720
- Asn-752
- Thr-805
- Thr-898
- Ser-917
- Asn-938
- Ser-985
- Ser-1018
- Thr-1029
- Ser-1044
- Thr-1047
- Ser-1053
- Asn-1074
- Ser-1150
- Thr-1211
- Asn-1221
- Thr-1238
- Thr-1247
- Thr-1283
- Thr-1302
- Ser-1481
- Thr-1520
- Asn-1559
- Ser-1594
- Asn-1703
- Ser-1781
- Ser-1868
- Ser-1926
- Thr-1990
- Asn-2010
- Thr-2053
- Ser-2090
- Asn-2209
Reported glycosite
Mass spectrometry observed peptide
-
- N-Linked / Complex
(avg mass : 1276.1699)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1397.2024)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1422.3129)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1567.4278)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1568.4559)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1641.5073)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1666.5605)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1770.6228)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1828.7029)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1869.7555)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1932.7652)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1932.7652)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1974.8459)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2078.9082)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2079.9363)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2119.9608)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2135.9602)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2177.0128)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2210.0397)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2224.0231)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2339.1552)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2370.1661)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2444.2456)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2516.3091)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2573.3611)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2575.3771)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2663.44)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2954.6979)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / High-Mannose
(avg mass : 1235.1173)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / High-Mannose
(avg mass : 1381.2603)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / High-Mannose
(avg mass : 1397.2597)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / High-Mannose
(avg mass : 1543.4027)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / High-Mannose
(avg mass : 1559.4021)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Hybrid
(avg mass : 1584.4553)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Hybrid
(avg mass : 1600.4547)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Hybrid
(avg mass : 1729.5702)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Hybrid
(avg mass : 1746.5977)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Hybrid
(avg mass : 1875.7132)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- N-Linked / Hybrid
(avg mass : 1891.7126)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 0
(avg mass : 221.2103)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 1
(avg mass : 383.3527)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 1
(avg mass : 674.6106)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 1
(avg mass : 674.6106)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 1
(avg mass : 965.8685)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 2
(avg mass : 586.5477)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 2
(avg mass : 748.6901)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 2
(avg mass : 877.8056)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 2
(avg mass : 1039.948)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 2
(avg mass : 1186.091)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 2
(avg mass : 1331.2059)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 2
(avg mass : 1696.5433)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 2
(avg mass : 1842.6863)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 4
(avg mass : 1243.143)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 4
(avg mass : 1534.4009)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 6
(avg mass : 1023.9486)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
-
- O-Linked / Core 9
(avg mass : 836.753)
- Blood Plasma (UBERON_0001969)
- Coagulation factor V / Homo sapiens
Source
Reported glycosite
- O-Linked / Core 9
(avg mass : 836.753)
Source
Reported glycosite
- O-Linked / Core 6
(avg mass : 1023.9486)
Source
Reported glycosite
- O-Linked / Core 4
(avg mass : 1534.4009)
Source
Reported glycosite
- O-Linked / Core 4
(avg mass : 1243.143)
Source
Reported glycosite
- O-Linked / Core 2
(avg mass : 1842.6863)
Source
Reported glycosite
- O-Linked / Core 2
(avg mass : 1696.5433)
Source
Reported glycosite
- O-Linked / Core 2
(avg mass : 1331.2059)
Source
Reported glycosite
- O-Linked / Core 2
(avg mass : 1186.091)
Source
Reported glycosite
- O-Linked / Core 2
(avg mass : 1039.948)
Source
Reported glycosite
- O-Linked / Core 2
(avg mass : 877.8056)
Source
Reported glycosite
- O-Linked / Core 2
(avg mass : 748.6901)
Source
Reported glycosite
- O-Linked / Core 2
(avg mass : 586.5477)
Source
Reported glycosite
- O-Linked / Core 1
(avg mass : 965.8685)
Source
Reported glycosite
- O-Linked / Core 1
(avg mass : 674.6106)
Source
Reported glycosite
- O-Linked / Core 1
(avg mass : 674.6106)
Source
Reported glycosite
- O-Linked / Core 1
(avg mass : 383.3527)
Source
Reported glycosite
- O-Linked / Core 0
(avg mass : 221.2103)
Source
Reported glycosite
- N-Linked / Hybrid
(avg mass : 1891.7126)
Source
Reported glycosite
- N-Linked / Hybrid
(avg mass : 1875.7132)
Source
Reported glycosite
- N-Linked / Hybrid
(avg mass : 1746.5977)
Source
Reported glycosite
- N-Linked / Hybrid
(avg mass : 1729.5702)
Source
Reported glycosite
- N-Linked / Hybrid
(avg mass : 1600.4547)
Source
Reported glycosite
- N-Linked / Hybrid
(avg mass : 1584.4553)
Source
Reported glycosite
- N-Linked / High-Mannose
(avg mass : 1559.4021)
Source
Reported glycosite
- N-Linked / High-Mannose
(avg mass : 1543.4027)
Source
Reported glycosite
- N-Linked / High-Mannose
(avg mass : 1397.2597)
Source
Reported glycosite
- N-Linked / High-Mannose
(avg mass : 1381.2603)
Source
Reported glycosite
- N-Linked / High-Mannose
(avg mass : 1235.1173)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2954.6979)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2663.44)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2575.3771)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2573.3611)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2516.3091)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2444.2456)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2370.1661)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2339.1552)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2224.0231)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2210.0397)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2177.0128)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2135.9602)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2119.9608)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2079.9363)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 2078.9082)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1974.8459)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1932.7652)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1932.7652)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1869.7555)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1828.7029)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1770.6228)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1666.5605)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1641.5073)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1568.4559)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1567.4278)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1422.3129)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1397.2024)
Source
Reported glycosite
- N-Linked / Complex
(avg mass : 1276.1699)
