Hinge-Region O-Glycosylation of Human Immunoglobulin G3 (IgG3) (2015)
Rosina Plomp, Gillian Dekkers, Yoann Rombouts, Remco Visser, Carolien A.M.Koeleman, Guinevere S.M.Kammeijer, Bas C.Jansen, Theo Rispens, Paul J.Hensbergen, Gestur Vidarsson, Manfred Wuhrer
Mol Cell Proteomics, 2015 vol.14(5):1373-1384
SNFG,
Text,
Oxford
taxonomy (1)
protein (4)
source (3)
structure (20)
composition (20)
disease (0)
reference (1)
site (11)
peptide (1)
- Homo sapiens (Human)
Taxonomy
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens P01860
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens P01860
- Immunoglobulin heavy constant gamma 2 / Homo sapiens P01859
- Immunoglobulin heavy constant gamma 3 / Homo sapiens P01860
Protein
- N-Linked / Complex / GlcNAc(?1-?)Man(a1-3)[GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
- N-Linked / Complex / Structure 2643
- N-Linked / Complex / Structure 2011
- N-Linked / Complex / Structure 10152
- N-Linked / Complex / Structure 2719
- N-Linked / Complex / Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc
- N-Linked / Complex / Structure 2888
- N-Linked / Complex / Structure 2104
- N-Linked / Complex / Structure 231
- N-Linked / Complex / Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
- N-Linked / Complex / Structure 10049
- N-Linked / Complex / Structure 1147
- N-Linked / Complex / Structure 908
- N-Linked / Complex / Structure 3507
- N-Linked / Complex / Structure 3446
- N-Linked / Complex / Structure 1523
- O-Linked / Core 1 / Gal(b1-3)GalNAc
- O-Linked / Core 1 / Gal(b1-3)GalNAc(a + "Neu5Ac(a"
- O-Linked / Core 1 / Structure 10127
- O-Linked / Core 1 / Structure 10140
Reported structure
- Hex:1 HexNAc:1 (avg mass : 383.3527 )
- Hex:1 HexNAc:1 NeuAc:1 (avg mass : 674.6106 )
- Hex:1 HexNAc:1 NeuAc:2 (avg mass : 965.8685 )
- Hex:2 HexNAc:2 NeuAc:2 (avg mass : 1331.2059 )
- Hex:3 HexNAc:4 (avg mass : 1317.2225 )
- Hex:3 HexNAc:4 dHex:1 (avg mass : 1463.3655 )
- Hex:3 HexNAc:5 (avg mass : 1520.4175 )
- Hex:3 HexNAc:5 dHex:1 (avg mass : 1666.5605 )
- Hex:4 HexNAc:4 (avg mass : 1479.3649 )
- Hex:4 HexNAc:4 NeuAc:1 (avg mass : 1770.6228 )
- Hex:4 HexNAc:4 dHex:1 (avg mass : 1625.5079 )
- Hex:4 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 1916.7658 )
- Hex:4 HexNAc:5 (avg mass : 1682.5599 )
- Hex:4 HexNAc:5 dHex:1 (avg mass : 1828.7029 )
- Hex:5 HexNAc:4 (avg mass : 1641.5073 )
- Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )
- Hex:5 HexNAc:4 dHex:1 (avg mass : 1787.6503 )
- Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )
- Hex:5 HexNAc:5 (avg mass : 1844.7023 )
- Hex:5 HexNAc:5 dHex:1 (avg mass : 1990.8453 )
Composition
Disease
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
Reported glycosite
- SCDTPPPCPR (10aa)
- P01860 Thr-122 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-137 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-137 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-152 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-152 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- P01860 Thr-137 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- P01860 Thr-122 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-152 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-122 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
Mass spectrometry observed peptide
-
- N-Linked / Complex
(avg mass : 1317.2225)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1463.3655)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1479.3649)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1520.4175)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1625.5079)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1641.5073)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1666.5605)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1682.5599)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1770.6228)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1787.6503)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1828.7029)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1844.7023)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1916.7658)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1932.7652)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 1990.8453)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- N-Linked / Complex
(avg mass : 2078.9082)
- Immunoglobulin heavy constant gamma 2 / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
-
- O-Linked / Core 1
(avg mass : 383.3527)
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
- SCDTPPPCPR (10aa)
- P01860 Thr-122 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-137 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-137 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-152 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-152 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- P01860 Thr-137 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- P01860 Thr-122 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-152 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-122 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
-
- O-Linked / Core 1
(avg mass : 674.6106)
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
- SCDTPPPCPR (10aa)
- P01860 Thr-122 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-137 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-137 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-152 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-152 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- P01860 Thr-137 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- P01860 Thr-122 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-152 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-122 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
-
- O-Linked / Core 1
(avg mass : 965.8685)
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- Immunoglobulin heavy constant gamma 3 / Homo sapiens
- SCDTPPPCPR (10aa)
- P01860 Thr-122 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-137 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-137 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-152 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-152 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- P01860 Thr-137 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- P01860 Thr-122 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-152 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-122 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
-
- O-Linked / Core 1
(avg mass : 1331.2059)
- HEK293-F (CVCL_6642)
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- SCDTPPPCPR (10aa)
- P01860 Thr-122 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-137 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-137 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-152 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-152 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- P01860 Thr-137 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
- P01860 Thr-122 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(g) / monoclonal) / Homo sapiens
- P01860 Thr-152 Immunoglobulin heavy constant gamma 3 / Homo sapiens
- P01860 Thr-122 Immunoglobulin gamma-3 (anti-GDob1 allotype G3m(s) / monoclonal) / Homo sapiens
Source
Reported glycosite
Mass spectrometry observed peptide
- O-Linked / Core 1
(avg mass : 1331.2059)
Reported glycosite
Mass spectrometry observed peptide
- O-Linked / Core 1
(avg mass : 965.8685)
Reported glycosite
Mass spectrometry observed peptide
- O-Linked / Core 1
(avg mass : 674.6106)
Reported glycosite
Mass spectrometry observed peptide
- O-Linked / Core 1
(avg mass : 383.3527)
Reported glycosite
- N-Linked / Complex
(avg mass : 2078.9082)
Reported glycosite
- N-Linked / Complex
(avg mass : 1990.8453)
Reported glycosite
- N-Linked / Complex
(avg mass : 1932.7652)
Reported glycosite
- N-Linked / Complex
(avg mass : 1916.7658)
Reported glycosite
- N-Linked / Complex
(avg mass : 1844.7023)
Reported glycosite
- N-Linked / Complex
(avg mass : 1828.7029)
Reported glycosite
- N-Linked / Complex
(avg mass : 1787.6503)
Reported glycosite
- N-Linked / Complex
(avg mass : 1770.6228)
Reported glycosite
- N-Linked / Complex
(avg mass : 1682.5599)
Reported glycosite
- N-Linked / Complex
(avg mass : 1666.5605)
Reported glycosite
- N-Linked / Complex
(avg mass : 1641.5073)
Reported glycosite
- N-Linked / Complex
(avg mass : 1625.5079)
Reported glycosite
- N-Linked / Complex
(avg mass : 1520.4175)
Reported glycosite
- N-Linked / Complex
(avg mass : 1479.3649)
Reported glycosite
- N-Linked / Complex
(avg mass : 1463.3655)
Reported glycosite
- N-Linked / Complex
(avg mass : 1317.2225)
