O-glycosylation mimics N-glycosylation in the 16-KDa fragment of bovine pro-opiomelanocortin. The major O-glycan attached to Thr-45 carries SO4-4GalNAc beta 1-4GlcNAc beta 1-, which is the archetypal non-reducing epitope in the N-glycans of pituitary glycohormones. (1994)
Siciliano R, Morris H, Bennett H, Dell A
J Biol Chem, 1994 vol.269:910-920
SNFG,
Text,
Oxford
taxonomy (1)
protein (1)
source (1)
structure (4)
composition (4)
disease (0)
reference (1)
site (1)
peptide (0)
- Bos taurus (Bovine)
Taxonomy
- Neurohypophysis (UBERON_0002198)
Source
- O-Linked / Core 1 / Gal(b1-3)GalNAc
- O-Linked / Core 2 / Gal(b1-4)GlcNAc(b1-6)[Gal(b1-3)]GalNAc
- O-Linked / Core 2 / HSO3(-4)GalNAc(b1-4)GlcNAc(b1-6)[Gal(b1-3)]GalNAc
- O-Linked / Undefined core / Fuc(?1-?)[GalNAc(?1-?)]GlcNAc(?1-6)[Gal(?1-3)]GalNAc
Reported structure
- Hex:1 HexNAc:1 (avg mass : 383.3527 )
- Hex:1 HexNAc:3 Su:1 (avg mass : 869.8069 )
- Hex:1 HexNAc:3 dHex:1 (avg mass : 935.8857 )
- Hex:2 HexNAc:2 (avg mass : 748.6901 )
Composition
Disease
- Corticotropin - lipotropin, npp peptide / Bos taurus
Reported glycosite
Mass spectrometry observed peptide
-
- O-Linked / Core 1
(avg mass : 383.3527)
- Neurohypophysis (UBERON_0002198)
- Corticotropin - lipotropin, npp peptide / Bos taurus
-
- O-Linked / Core 2
(avg mass : 748.6901)
- Neurohypophysis (UBERON_0002198)
- Corticotropin - lipotropin, npp peptide / Bos taurus
-
- O-Linked / Core 2
(avg mass : 869.8069)
- Neurohypophysis (UBERON_0002198)
- Corticotropin - lipotropin, npp peptide / Bos taurus
-
- O-Linked / Undefined core
(avg mass : 935.8857)
- Neurohypophysis (UBERON_0002198)
- Corticotropin - lipotropin, npp peptide / Bos taurus
Source
Reported glycosite
- O-Linked / Undefined core
(avg mass : 935.8857)
Source
Reported glycosite
- O-Linked / Core 2
(avg mass : 869.8069)
Source
Reported glycosite
- O-Linked / Core 2
(avg mass : 748.6901)
Source
Reported glycosite
- O-Linked / Core 1
(avg mass : 383.3527)