Structures of the asparagine-linked sugar chain of glucose transporter from human erythrocytes. (1990)

Taxonomy

• Homo sapiens (Human)

Protein

• Solute carrier family 2, facilitated glucose transporter, member 1 / Homo sapiens    P11166

Source

• Erythrocyte (CL_0000232)   Plasma Membrane (GO_0005886)  

Reported structure

• N-Linked / Complex / Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-3)[Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"Where j+k=14 & j,k>=1"
• N-Linked / Complex / Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-3)[Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"Where j+k=14 & j,k>=1"
• N-Linked / Complex / Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-3)[Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-6)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"Where j+k=14 & j,k>=1"
• N-Linked / Complex / NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-?)[Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"Where j+k=14 & j,k>=1"
• N-Linked / Complex / Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-3)[Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-6)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"Where j+k=14 & j,k>=1"
• N-Linked / Complex / NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-?)[Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"Where j+k=14 & j,k>=1"
• N-Linked / Complex / NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-?)[Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-?)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"Where j+k=14 & j,k>=1"
• N-Linked / Complex / NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-3)[NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"Where j+k=14 & k,j>=1"
• N-Linked / Complex / NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-?)[Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-?)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"Where j+k=14 & j,k>=1"
• N-Linked / Complex / NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-3)[NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"Where j+k=14 & j,k>=1"
• N-Linked / Complex / NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-3)[NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-6)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"Where j+k=14 & j,k>=1"
• N-Linked / Complex / NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}kGlcNAc(b1-2)Man(a1-3)[NeuAc(a2-?)Gal(b1-4){GlcNAc(b1-3)Gal(b1-4)}jGlcNAc(b1-2)Man(a1-6)][GlcNAc(b1-4)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"Where j+k=14 & j,k>=1"
• N-Linked / High-Mannose / Man(a1-2)Man(a1-3)[Man(a1-2)Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• Hex:9 HexNAc:2 (avg mass : 1883.6869 )
• Hex:19 HexNAc:18 (avg mass : 6756.2309 )
• Hex:19 HexNAc:18 NeuAc:1 (avg mass : 7047.4888 )
• Hex:19 HexNAc:18 NeuAc:2 (avg mass : 7338.7467 )
• Hex:19 HexNAc:18 dHex:1 (avg mass : 6902.3739 )
• Hex:19 HexNAc:18 dHex:1 NeuAc:1 (avg mass : 7193.6318 )
• Hex:19 HexNAc:18 dHex:1 NeuAc:2 (avg mass : 7484.8897 )
• Hex:19 HexNAc:19 (avg mass : 6959.4259 )
• Hex:19 HexNAc:19 NeuAc:1 (avg mass : 7250.6838 )
• Hex:19 HexNAc:19 NeuAc:2 (avg mass : 7541.9417 )
• Hex:19 HexNAc:19 dHex:1 (avg mass : 7105.5689 )
• Hex:19 HexNAc:19 dHex:1 NeuAc:1 (avg mass : 7396.8268 )
• Hex:19 HexNAc:19 dHex:1 NeuAc:2 (avg mass : 7688.0847 )

Disease

Reference

• Structures of the asparagine-linked sugar chain of glucose transporter from human erythrocytes. (1990 - Endo T, Kasahara M, Kobata A) / Status : Reviewed

Reported glycosite

• Solute carrier family 2, facilitated glucose transporter, member 1 / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide