Dickkopf-related protein 3

Taxonomy

• Homo sapiens (Human)

Protein

• Dickkopf-related protein 3 / Homo sapiens    Q9UBP4

Source

• Blood Serum (UBERON_0001977)  
• Cerebrospinal Fluid Secretion (GO_0033326)  

Reported structure

Composition

• Hex:1 HexNAc:1 (avg mass : 383.3527 )
• Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )
• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )
• Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )
• Hex:6 HexNAc:6 dHex:1 NeuAc:2 (avg mass : 2938.6985 )

Disease

• Prostate cancer (DOID:10283)

Reference

• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
• LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins (2013 - Halim A, Rüetschi U, Larson G, Nilsson J) / Status : Reviewed

Reported glycosite

• Dickkopf-related protein 3 / Homo sapiens
  •        Thr-26
  •        Thr-28
  •        Asn-106
  •        Asn-120

Mass spectrometry observed peptide

• VGNNTIHVHR (10aa)
  •    Q9UBP4    Asn-106
• ITNNQTGQMVFSETVITSVGDEEGR (25aa)
  •    Q9UBP4    Asn-120