GlyConnect

Taxonomy (1) Protein (1) Source (3) Structure (1) Composition (6) Disease (3) Site (4) Peptide (4)

Taxonomy

Homo sapiens (Human)

Protein

Complement component c6 / Homo sapiens P13671

Source

Reported structure

N-Linked / Complex / NeuAc(?2-?)Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[NeuAc(?2-?)Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

Disease

Reported glycosite

Complement component c6 / Homo sapiens :
- Asn-59
- Asn-324
- Asn-855
- Asn-910

Mass spectrometry validated peptide

YYQENFCEQICSK (13aa)
- P13671 Asn-59
VLNFTTK (7aa)
- P13671 Asn-324
LSSNSTK (7aa)
- P13671 Asn-855
TLNICEVGTIR (11aa)
- P13671 Asn-910

- N-Linked / Complex (avg mass : 2224.0231 )

- Hex:5 HexNAc:4 dHex:2 NeuAc:1 (avg mass : 2225.0512 )
- Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )
- Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )
- Hex:4 HexNAc:6 dHex:2 (avg mass : 2178.0409 )
- Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )
- Hex:6 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2735.5035 )

Cross-references

UniProtKB : P13671

neXtProt : NX_P13671

GeneCards : C6

3D structure from PDB

Select a PDB entry

Github Wiki

3D visualization by LiteMol

References (3)

Large-scale intact glycopeptide identification by Mascot database search (2018)
Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede
Pubmed : 29391424 DOI : 10.1038/s41598-018-20331-2
Status : Unreviewed

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed

Computational framework for identification of intact glycopeptides in complex samples (2014)
Mayampurath A, Yu CY, Song E, Balan J, Mechref Y, Tang H.
Pubmed : 24279413 DOI : 10.1021/ac402338u
Status : Reviewed