Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Plasma (UBERON_0001969)  

Reported structure

• N-Linked / Complex / Neu?c(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[Neu?c(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

Composition

• Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )

Disease

• Myeloma, Multiple (DOID:9538)

Reference

• Structure of the carbohydrate units of IgE immunoglobulin. II. Sequence of the sialic acid-containing glycopeptides. (1974 - Baenziger J, Kornfeld S, Kochwa S) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / High-Mannose / Structure 314

Composition

• Hex:7 HexNAc:2 (avg mass : 1559.4021 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 350

Composition

• Hex:5 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2573.3611 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ Man"

Composition

• Hex:4 HexNAc:2 (avg mass : 1072.9749 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 1147

Composition

• Hex:5 HexNAc:5 (avg mass : 1844.7023 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 1344

Composition

• Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-3)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• Hex:5 HexNAc:2 (avg mass : 1235.1173 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)
• Hypersensitivity reaction disease (DOID:0060056)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed
• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 1497

Composition

• Hex:4 HexNAc:3 dHex:1 (avg mass : 1422.3129 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 1519

Composition

• Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Plasma (UBERON_0001969)  

Reported structure

• N-Linked / No-core / Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc(a1-3)[Man(a1-2)Man(a1-6)]Man(b1-4)GlcNAc

Composition

• Hex:6 HexNAc:2 (avg mass : 1397.2597 )

Disease

• Myeloma, Multiple (DOID:9538)

Reference

• Structure of the carbohydrate units of IgE immunoglobulin. I. Over-all composition, glycopeptide isolation, and structure of the high mannose oligosaccharide unit. (1974 - Baenziger J, Kornfeld S, Kochwa S) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 1850

Composition

• Hex:3 HexNAc:3 dHex:1 (avg mass : 1260.1705 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 1994

Composition

• Hex:4 HexNAc:3 (avg mass : 1276.1699 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 2011

Composition

• Hex:4 HexNAc:4 (avg mass : 1479.3649 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• Hex:6 HexNAc:2 (avg mass : 1397.2597 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Plasma (UBERON_0001969)  

Reported structure

• N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

Composition

• Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )

Disease

• Myeloma, Multiple (DOID:9538)

Reference

• Structure of the carbohydrate units of IgE immunoglobulin. II. Sequence of the sialic acid-containing glycopeptides. (1974 - Baenziger J, Kornfeld S, Kochwa S) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / High-Mannose / Structure 2636

Composition

• Hex:8 HexNAc:2 (avg mass : 1721.5445 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

Composition

• Hex:5 HexNAc:4 dHex:1 (avg mass : 1787.6503 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)
• Hypersensitivity reaction disease (DOID:0060056)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed
• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 2643

Composition

• Hex:3 HexNAc:4 dHex:1 (avg mass : 1463.3655 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 2719

Composition

• Hex:4 HexNAc:4 dHex:1 (avg mass : 1625.5079 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Pauci-Mannose / Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ GlcNAc"

Composition

• Hex:3 HexNAc:3 (avg mass : 1114.0275 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / NeuAc(?2-?)Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[NeuAc(?2-?)Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 3446

Composition

• Hex:5 HexNAc:5 dHex:1 (avg mass : 1990.8453 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)
• Hypersensitivity reaction disease (DOID:0060056)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed
• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• Hex:5 HexNAc:4 (avg mass : 1641.5073 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / High-Mannose / Structure 3485

Composition

• Hex:6 HexNAc:2 (avg mass : 1397.2597 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / High-Mannose / Structure 10029

Composition

• Hex:9 HexNAc:2 (avg mass : 1883.6869 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10128

Composition

• Hex:4 HexNAc:4 dHex:1 (avg mass : 1625.5079 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10151

Composition

• Hex:6 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2444.2456 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10186

Composition

• Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10203

Composition

• Hex:5 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2282.1032 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Hybrid / Structure 10205

Composition

• Hex:5 HexNAc:3 (avg mass : 1438.3123 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10231

Composition

• Hex:5 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2282.1032 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10246

Composition

• Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10248

Composition

• Hex:5 HexNAc:5 NeuAc:1 (avg mass : 2135.9602 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10275

Composition

• Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / High-Mannose / Structure 10291

Composition

• Hex:7 HexNAc:2 (avg mass : 1559.4021 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10293

Composition

• Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / High-Mannose / Structure 10300

Composition

• Hex:8 HexNAc:2 (avg mass : 1721.5445 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10303

Composition

• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )

Disease

• Hypersensitivity reaction disease (DOID:0060056)

Reference

• The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin (2004 - James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 10310

Composition

• Hex:4 HexNAc:5 dHex:1 (avg mass : 1828.7029 )

Disease

• Atopic dermatitis (DOID:3310)
• Hyper IgE syndrome (DOID:0080545)

Reference

• Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels, (2014 - Atfa Sassi, Sandra Lazaroski, Gang Wu, Stuart M. Haslam, Manfred Fliegauf, Fethi Mellouli, Turkan Patiroglu, Ekrem Unal, Mehmet Akif Ozdemir, Zineb Jouhadi, Khadija Khadir, Leila Ben-Khemis, Meriem Ben-Ali, Imen Ben-Mustapha, Lamia Borchani, Dietmar Pfeifer, Thilo Jakob, Monia Khemiri, A. Charlotta Asplund, Manuela O. Gustafsson, Karin E. Lundin, Elin Falk-Sörqvist, Lotte N. Moens, Hatice Eke Gungor, Karin R. Engelhardt, Magdalena Dziadzio, Hans Stauss, Bernhard Fleckenstein, Rebecca Meier, Khairunnadiya Prayitno, Andrea Maul-Pavicic, Sandra Schaffer, Mirzokhid Rakhmanov, Philipp Henneke, Helene Kraus, Hermann Eibel, Uwe Kölsch, Sellama Nadifi, Mats Nilsson, Mohamed Bejaoui, Alejandro A. Schäffer, C.I. Edvard Smith, Anne Dell, Mohamed-Ridha Barbouche, Bodo Grimbacher) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 138

Composition

• Hex:7 HexNAc:6 dHex:1 NeuAc:1 (avg mass : 2809.583 )

Disease

• IgE myeloma (DOID:9538)
• Myeloma, Multiple (DOID:9538)

Reference

• Site-specific N-glycosylation analysis of human immunoglobulin E. (2014 - Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CA, Deelder AM, Wuhrer M) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 350

Composition

• Hex:5 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2573.3611 )

Disease

• Control/Healthy
• Hyperimmune condition

Reference

• Site-specific N-glycosylation analysis of human immunoglobulin E. (2014 - Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CA, Deelder AM, Wuhrer M) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 923

Composition

• Hex:6 HexNAc:5 dHex:1 (avg mass : 2152.9877 )

Disease

• Hyperimmune condition

Reference

• Site-specific N-glycosylation analysis of human immunoglobulin E. (2014 - Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CA, Deelder AM, Wuhrer M) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 1147

Composition

• Hex:5 HexNAc:5 (avg mass : 1844.7023 )

Disease

• Hyperimmune condition

Reference

• Site-specific N-glycosylation analysis of human immunoglobulin E. (2014 - Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CA, Deelder AM, Wuhrer M) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 1149

Composition

• Hex:5 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2282.1032 )

Disease

• Control/Healthy
• Hyperimmune condition
• IgE myeloma (DOID:9538)
• Myeloma, Multiple (DOID:9538)

Reference

• Site-specific N-glycosylation analysis of human immunoglobulin E. (2014 - Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CA, Deelder AM, Wuhrer M) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 1519

Composition

• Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )

Disease

• Control/Healthy
• Hyperimmune condition
• IgE myeloma (DOID:9538)
• Myeloma, Multiple (DOID:9538)

Reference

• Site-specific N-glycosylation analysis of human immunoglobulin E. (2014 - Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CA, Deelder AM, Wuhrer M) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 1523

Composition

• Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )

Disease

• Control/Healthy
• Hyperimmune condition
• IgE myeloma (DOID:9538)
• Myeloma, Multiple (DOID:9538)

Reference

• Site-specific N-glycosylation analysis of human immunoglobulin E. (2014 - Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CA, Deelder AM, Wuhrer M) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 1712

Composition

• Hex:6 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2735.5035 )

Disease

• Control/Healthy
• Hyperimmune condition
• IgE myeloma (DOID:9538)
• Myeloma, Multiple (DOID:9538)

Reference

• Site-specific N-glycosylation analysis of human immunoglobulin E. (2014 - Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CA, Deelder AM, Wuhrer M) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• HEK293T (CVCL_0063)  

Reported structure

• N-Linked / Complex / Gal(?1-?)GlcNAc(?1-?)[Gal(?1-?)GlcNAc(?1-?)]Man(a1-3)[Gal(?1-?)GlcNAc(?1-?)[Gal(?1-?)GlcNAc(?1-?)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

Composition

• Hex:7 HexNAc:6 dHex:1 (avg mass : 2518.3251 )

Disease

Reference

• A single glycan on IgE is indispensable for initiation of anaphylaxis (2015 - Kai-Ting C. Shade, Barbara Platzer, Nathaniel Washburn, Vinidhra Mani, Yannic C. Bartsch, Michelle Conroy, Jose D. Pagan, Carlos Bosques, Thorsten R. Mempel, Edda Fiebiger, Robert M. Anthony) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Structure 2089

Composition

• Hex:6 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2444.2456 )

Disease

• Control/Healthy
• Hyperimmune condition
• IgE myeloma (DOID:9538)
• Myeloma, Multiple (DOID:9538)

Reference

• Site-specific N-glycosylation analysis of human immunoglobulin E. (2014 - Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CA, Deelder AM, Wuhrer M) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Asn-21

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin epsilon chain c region / Homo sapiens    P01854

Source

• Blood Serum (UBERON_0001977)  
• HEK293T (CVCL_0063)  

Reported structure

• N-Linked / Complex / Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

Composition

• Hex:5 HexNAc:4 dHex:1 (avg mass : 1787.6503 )

Disease

• Control/Healthy
• Hyperimmune condition

Reference

• A single glycan on IgE is indispensable for initiation of anaphylaxis (2015 - Kai-Ting C. Shade, Barbara Platzer, Nathaniel Washburn, Vinidhra Mani, Yannic C. Bartsch, Michelle Conroy, Jose D. Pagan, Carlos Bosques, Thorsten R. Mempel, Edda Fiebiger, Robert M. Anthony) / Status : Reviewed
• Site-specific N-glycosylation analysis of human immunoglobulin E. (2014 - Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CA, Deelder AM, Wuhrer M) / Status : Reviewed

Reported glycosite

• Immunoglobulin epsilon chain c region / Homo sapiens
  •        Undefined site
  •        Asn-21

Mass spectrometry observed peptide