Taxonomy

• Homo sapiens (Human)

Protein

• Proteoglycan 4 (lubricin) / Homo sapiens    Q92954

Source

• Synovial Fluid (UBERON_0001090)  

Reported structure

• O-Linked / Core 1 / Gal(b1-3)GalNAc(a + "Neu5Ac(a"

Composition

• Hex:1 HexNAc:1 NeuAc:1 (avg mass : 674.6106 )

Disease

• Arthritis, Rheumatoid (DOID:7148)
• Osteoarthritis (DOID:8398)

Reference

• The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis (2014 - Ali L, Flowers SA, Jin C, Bennet EP, Ekwall AK, Karlsson NG) / Status : Reviewed

Reported glycosite

• Proteoglycan 4 (lubricin) / Homo sapiens
  •        Thr-324

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Proteoglycan 4 (lubricin) / Homo sapiens    Q92954

Source

• Synovial Fluid (UBERON_0001090)  

Reported structure

• O-Linked / Core 1 / Gal(b1-3)GalNAc

Composition

• Hex:1 HexNAc:1 (avg mass : 383.3527 )

Disease

• Arthritis, Rheumatoid (DOID:7148)
• Osteoarthritis (DOID:8398)

Reference

• The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis (2014 - Ali L, Flowers SA, Jin C, Bennet EP, Ekwall AK, Karlsson NG) / Status : Reviewed

Reported glycosite

• Proteoglycan 4 (lubricin) / Homo sapiens
  •        Thr-324

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Proteoglycan 4 (lubricin) / Homo sapiens    Q92954

Source

• Synovial Fluid (UBERON_0001090)  

Reported structure

• O-Linked / Core 0 / GalNAc

Composition

• HexNAc:1 (avg mass : 221.2103 )

Disease

• Arthritis, Rheumatoid (DOID:7148)
• Osteoarthritis (DOID:8398)

Reference

• The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis (2014 - Ali L, Flowers SA, Jin C, Bennet EP, Ekwall AK, Karlsson NG) / Status : Reviewed

Reported glycosite

• Proteoglycan 4 (lubricin) / Homo sapiens
  •        Thr-324

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Proteoglycan 4 (lubricin) / Homo sapiens    Q92954

Source

• Synovial Fluid (UBERON_0001090)  

Reported structure

• O-Linked / Core 1 / NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc

Composition

• Hex:1 HexNAc:1 NeuAc:2 (avg mass : 965.8685 )

Disease

• Arthritis, Rheumatoid (DOID:7148)
• Osteoarthritis (DOID:8398)

Reference

• The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis (2014 - Ali L, Flowers SA, Jin C, Bennet EP, Ekwall AK, Karlsson NG) / Status : Reviewed

Reported glycosite

• Proteoglycan 4 (lubricin) / Homo sapiens
  •        Thr-324

Mass spectrometry observed peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Proteoglycan 4 (lubricin) / Homo sapiens    Q92954

Source

• Synovial Fluid (UBERON_0001090)  

Reported structure

• O-Linked / Core 2 / Gal(b1-4)GlcNAc(b1-6)[Gal(b1-3)]GalNAc

Composition

• Hex:2 HexNAc:2 (avg mass : 748.6901 )

Disease

• Arthritis, Rheumatoid (DOID:7148)
• Osteoarthritis (DOID:8398)

Reference

• The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis (2014 - Ali L, Flowers SA, Jin C, Bennet EP, Ekwall AK, Karlsson NG) / Status : Reviewed

Reported glycosite

• Proteoglycan 4 (lubricin) / Homo sapiens
  •        Thr-324

Mass spectrometry observed peptide