taxonomy (1)
protein (1)
source (2)
structure (7)
composition (8)
disease (3)
reference (2)
site (44)
peptide (1)
- Homo sapiens (Human)
Taxonomy
- O-Linked / Core 0 / GalNAc
- O-Linked / Core 1 / Gal(b1-3)GalNAc
- O-Linked / Core 1 / Gal(b1-3)GalNAc(a + "Neu5Ac(a"
- O-Linked / Core 1 / NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc
- O-Linked / Core 2 / Gal(b1-3)[GlcNAc(b1-6)]GalNAc
- O-Linked / Core 2 / Gal(b1-4)GlcNAc(b1-6)[Gal(b1-3)]GalNAc
- O-Linked / Undefined core / GlcNAc(?1-?)GalNAc
Reported structure
- HexNAc:1 (avg mass : 221.2103 )
- HexNAc:2 (avg mass : 424.4053 )
- Hex:1 HexNAc:1 (avg mass : 383.3527 )
- Hex:1 HexNAc:1 NeuAc:1 (avg mass : 674.6106 )
- Hex:1 HexNAc:1 NeuAc:2 (avg mass : 965.8685 )
- Hex:1 HexNAc:2 (avg mass : 586.5477 )
- Hex:2 HexNAc:2 (avg mass : 748.6901 )
- Hex:5 HexNAc:2 (avg mass : 1235.1173 )
Composition
- Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
- The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis (2014 - Ali L, Flowers SA, Jin C, Bennet EP, Ekwall AK, Karlsson NG) / Status : Reviewed
Reference
-
Proteoglycan 4 (lubricin) / Homo sapiens
- Ser-123
- Ser-136
- Thr-240
- Thr-253
- Thr-277
- Thr-291
- Thr-305
- Ser-306
- Thr-310
- Ser-317
- Thr-324
- Thr-332
- Thr-338
- Thr-367
- Thr-407
- Thr-415
- Ser-427
- Thr-430
- Thr-485
- Ser-529
- Thr-532
- Thr-540
- Thr-541
- Ser-553
- Thr-555
- Thr-619
- Thr-627
- Thr-676
- Ser-812
- Thr-829
- Ser-892
- Thr-900
- Thr-930
- Thr-931
- Ser-962
- Thr-963
- Thr-968
- Thr-975
- Thr-978
- Thr-979
- Thr-980
- Thr-1039
- Asn-1159
- Thr-1161
Reported glycosite
- NGTLVAFR (8aa)
Mass spectrometry observed peptide
-
- O-Linked / Core 0
(avg mass : 221.2103)
- Synovial Fluid (UBERON_0001090)
- Proteoglycan 4 (lubricin) / Homo sapiens
-
- O-Linked / Core 1
(avg mass : 383.3527)
- Synovial Fluid (UBERON_0001090)
- Proteoglycan 4 (lubricin) / Homo sapiens
-
- O-Linked / Core 1
(avg mass : 674.6106)
- Synovial Fluid (UBERON_0001090)
- Proteoglycan 4 (lubricin) / Homo sapiens
-
- O-Linked / Core 1
(avg mass : 965.8685)
- Synovial Fluid (UBERON_0001090)
- Proteoglycan 4 (lubricin) / Homo sapiens
-
- O-Linked / Core 2
(avg mass : 586.5477)
- Synovial Fluid (UBERON_0001090)
- Proteoglycan 4 (lubricin) / Homo sapiens
-
- O-Linked / Core 2
(avg mass : 748.6901)
- Synovial Fluid (UBERON_0001090)
- Proteoglycan 4 (lubricin) / Homo sapiens
-
- O-Linked / Undefined core
(avg mass : 424.4053)
- Synovial Fluid (UBERON_0001090)
- Proteoglycan 4 (lubricin) / Homo sapiens
-
- Hex:5 HexNAc:2 / N-Linked
(avg mass : 1235.1173)
- Mammary Gland (UBERON_0001911)
- Cancer, breast (DOID:1612)
- Proteoglycan 4 (lubricin) / Homo sapiens
- NGTLVAFR (8aa)
Source
Suggested structure
Disease
Reported glycosite
Mass spectrometry observed peptide
- Hex:5 HexNAc:2 / N-Linked
(avg mass : 1235.1173)
Source
Reported glycosite
Suggested glycosite
- O-Linked / Undefined core
(avg mass : 424.4053)
Source
Reported glycosite
Suggested glycosite
- O-Linked / Core 2
(avg mass : 748.6901)
Source
Reported glycosite
Suggested glycosite
- O-Linked / Core 2
(avg mass : 586.5477)
Source
Reported glycosite
Suggested glycosite
- O-Linked / Core 1
(avg mass : 965.8685)
Source
Reported glycosite
Suggested glycosite
- O-Linked / Core 1
(avg mass : 674.6106)
Source
Reported glycosite
Suggested glycosite
- O-Linked / Core 1
(avg mass : 383.3527)
Source
Reported glycosite
Suggested glycosite
- O-Linked / Core 0
(avg mass : 221.2103)
