Fractalkine

Taxonomy

• Homo sapiens (Human)

Protein

• Fractalkine / Homo sapiens    P78423

Source

• Mammary Gland (UBERON_0001911)  
• Urine (UBERON_0001088)  
• Cerebrospinal Fluid Secretion (GO_0033326)  

Reported structure

Composition

• Hex:1 HexNAc:1 (avg mass : 383.3527 )
• Hex:1 HexNAc:1 NeuAc:2 (avg mass : 965.8685 )
• Hex:6 HexNAc:6 (avg mass : 2210.0397 )

Disease

• Cancer, breast (DOID:1612)
• Prostate cancer (DOID:10283)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Distinct urinary glycoprotein signatures in prostate cancer patients (2018 - Rebeca Kawahara, Fabio Ortega, Livia Rosa-Fernandes, Vanessa Guimarães, Daniel Quina, Willian Nahas, Veit Schwämmle, Miguel Srougi, Katia R.M. Leite, Morten Thaysen-Andersen, Martin R. Larsen and Giuseppe Palmisano) / Status : Unreviewed
• Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD (2012 - Halim A, Nilsson J, Rüetschi U, Hesse C, Larson G) / Status : Reviewed
• Enrichment of glycopeptides for glycan structure and attachment site identification (2009 - Nilsson J, Rüetschi U, Halim A, Hesse C, Carlsohn E, Brinkmalm G, Larson G.) / Status : Reviewed

Reported glycosite

• Fractalkine / Homo sapiens
  •        Asn-33
  •        Thr-183
  •        Ser-253
  •        Thr-329

Mass spectrometry observed peptide

• CNITCSK (7aa)
  •    P78423    Asn-33
• AQDGGPVGTELFR (13aa)
  •    P78423    Thr-183