Hepatocyte growth factor receptor

Taxonomy

• Homo sapiens (Human)

Protein

• Hepatocyte growth factor receptor / Homo sapiens    P08581

Source

• Blood Serum (UBERON_0001977)  
• Umbilical Vein (UBERON_0002066)   Endothelial Cell of Umbilical Vein (CL_0002618)  

Reported structure

Composition

• Hex:4 HexNAc:3 NeuAc:1 (avg mass : 1567.4278 )
• Hex:4 HexNAc:4 NeuAc:1 (avg mass : 1770.6228 )
• Hex:4 HexNAc:4 NeuAc:2 (avg mass : 2061.8807 )
• Hex:5 HexNAc:3 NeuAc:1 (avg mass : 1729.5702 )
• Hex:5 HexNAc:3 dHex:1 NeuAc:1 (avg mass : 1875.7132 )
• Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )
• Hex:5 HexNAc:4 dHex:2 NeuAc:1 (avg mass : 2225.0512 )
• Hex:5 HexNAc:4 dHex:2 NeuAc:2 (avg mass : 2516.3091 )
• Hex:5 HexNAc:6 dHex:1 (avg mass : 2194.0403 )
• Hex:6 HexNAc:4 NeuAc:1 (avg mass : 2094.9076 )
• Hex:6 HexNAc:5 NeuAc:1 (avg mass : 2298.1026 )
• Hex:6 HexNAc:5 NeuAc:2 (avg mass : 2589.3605 )
• Hex:6 HexNAc:5 NeuAc:3 (avg mass : 2880.6184 )
• Hex:6 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2735.5035 )
• Hex:7 HexNAc:6 NeuAc:1 (avg mass : 2663.44 )
• Hex:7 HexNAc:6 NeuAc:2 (avg mass : 2954.6979 )
• Hex:7 HexNAc:6 NeuAc:3 (avg mass : 3245.9558 )

Disease

• Prostate cancer (DOID:10283)

Reference

• Site-Specific Profiling of Serum Glycoproteins Using N-Linked Glycan and Glycosite Analysis Revealing Atypical N-Glycosylation Sites on Albumin and α-1B-Glycoprotein (2018 - Shisheng Sun, Yingwei Hu, Li Jia, Shadi Toghi Eshghi, Yang Liu, Punit Shah, Hui Zhang) / Status : Unreviewed
• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
• Glycoproteomic analysis of the secretome of human endothelial cells (2013 - Yin X, Bern M, Xing Q, Ho J, Viner R, Mayr M.) / Status : Reviewed

Reported glycosite

• Hepatocyte growth factor receptor / Homo sapiens
  •        Asn-106
  •        Asn-405
  •        Asn-785
  •        Asn-930
  •        Asn-998
  •        Asn-1171

Mass spectrometry observed peptide

• ANLSGGVWK (9aa)
  •    P08581    Asn-106
• NFTVACQHR (9aa)
  •    P08581    Asn-785
• SVSPTTEMVSNESVDYR (17aa)
  •    P08581    Asn-998
• NETHNPTVK (9aa)
  •    P08581    Asn-1171