Pigment epithelium-derived factor

Taxonomy

• Homo sapiens (Human)

Protein

• Pigment epithelium-derived factor / Homo sapiens    P36955

Source

• Blood Plasma (UBERON_0001969)  
• Blood Serum (UBERON_0001977)  
• Mammary Gland (UBERON_0001911)  

Reported structure

• N-Linked / Complex / Structure 3507

Composition

• Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )
• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )
• Hex:5 HexNAc:4 dHex:1 (avg mass : 1787.6503 )
• Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )
• Hex:5 HexNAc:4 dHex:2 NeuAc:1 (avg mass : 2225.0512 )
• Hex:12 HexNAc:2 (avg mass : 2370.1141 )

Disease

• Cancer, breast (DOID:1612)
• Esophageal cancer (DOID:5041)
• Prostate cancer (DOID:10283)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
• Computational framework for identification of intact glycopeptides in complex samples (2014 - Mayampurath A, Yu CY, Song E, Balan J, Mechref Y, Tang H.) / Status : Reviewed

Reported glycosite

• Pigment epithelium-derived factor / Homo sapiens
  •        Asn-285

Mass spectrometry observed peptide

• VTQNLTLIEESLTSEFIHDIDR (22aa)
  •    P36955    Asn-285     Pigment epithelium-derived factor / Homo sapiens
• VTQNLTLIEESLTSEFIHDIDRELK (25aa)
  •    P36955    Asn-285     Pigment epithelium-derived factor / Homo sapiens