GlyConnect

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Site	Core / Type	Cartoon	Composition	Biological associations
Asn-219	N-Linked / Complex		Hex:4 HexNAc:5 dHex:1 NeuAc:1	taxonomy (1) protein (1) source (1) structure (1) composition (1) disease (1) reference (1) site (1) peptide (0) Taxonomy Homo sapiens (Human) Protein Tissue-type plasminogen activator / Homo sapiens P00750 Source Skin of Body (UBERON_0002097) HMCB (CVCL_3317) Reported structure N-Linked / Complex / Gal(?1-?)GlcNAc(b1-2)Man(a1-?)[GalNAc(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc+"+ NeuAc(a2-6)" Composition Hex:4 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2119.9608 ) Disease Melanoma (DOID:1909) Reference A novel sialylated N-acetylgalactosamine-containing oligosaccharide is the major complex-type structure present in Bowes melanoma tissue plasminogen activator. (1991 - Chan A, Morris H, Panico M, Etienne A, Rogers M, Gaffney P, Creighton-Kempsford L, Dell A) / Status : Reviewed Reported glycosite Tissue-type plasminogen activator / Homo sapiens Asn-219 Mass spectrometry observed peptide
Asn-219	N-Linked / Complex		Hex:3 HexNAc:6 dHex:1 NeuAc:1	taxonomy (1) protein (1) source (1) structure (1) composition (1) disease (1) reference (1) site (1) peptide (0) Taxonomy Homo sapiens (Human) Protein Tissue-type plasminogen activator / Homo sapiens P00750 Source Skin of Body (UBERON_0002097) HMCB (CVCL_3317) Reported structure N-Linked / Complex / NeuAc(a2-6)GalNAc(b1-4)GlcNAc(b1-2)Man(a1-?)[GalNAc(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc Composition Hex:3 HexNAc:6 dHex:1 NeuAc:1 (avg mass : 2161.0134 ) Disease Melanoma (DOID:1909) Reference A novel sialylated N-acetylgalactosamine-containing oligosaccharide is the major complex-type structure present in Bowes melanoma tissue plasminogen activator. (1991 - Chan A, Morris H, Panico M, Etienne A, Rogers M, Gaffney P, Creighton-Kempsford L, Dell A) / Status : Reviewed Reported glycosite Tissue-type plasminogen activator / Homo sapiens Asn-219 Mass spectrometry observed peptide
Asn-219	N-Linked / Complex		Hex:3 HexNAc:6 dHex:1 NeuAc:2	taxonomy (1) protein (1) source (1) structure (1) composition (1) disease (1) reference (1) site (1) peptide (0) Taxonomy Homo sapiens (Human) Protein Tissue-type plasminogen activator / Homo sapiens P00750 Source Skin of Body (UBERON_0002097) HMCB (CVCL_3317) Reported structure N-Linked / Complex / NeuAc(a2-6)GalNAc(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-6)GalNAc(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc Composition Hex:3 HexNAc:6 dHex:1 NeuAc:2 (avg mass : 2452.2713 ) Disease Melanoma (DOID:1909) Reference A novel sialylated N-acetylgalactosamine-containing oligosaccharide is the major complex-type structure present in Bowes melanoma tissue plasminogen activator. (1991 - Chan A, Morris H, Panico M, Etienne A, Rogers M, Gaffney P, Creighton-Kempsford L, Dell A) / Status : Reviewed Reported glycosite Tissue-type plasminogen activator / Homo sapiens Asn-219 Mass spectrometry observed peptide
Asn-219	N-Linked / Complex		Hex:3 HexNAc:6 dHex:1	taxonomy (1) protein (1) source (1) structure (1) composition (1) disease (1) reference (1) site (1) peptide (0) Taxonomy Homo sapiens (Human) Protein Tissue-type plasminogen activator / Homo sapiens P00750 Source Skin of Body (UBERON_0002097) HMCB (CVCL_3317) Reported structure N-Linked / Complex / GalNAc(b1-4)GlcNAc(b1-2)Man(a1-3)[GalNAc(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc Composition Hex:3 HexNAc:6 dHex:1 (avg mass : 1869.7555 ) Disease Melanoma (DOID:1909) Reference A novel sialylated N-acetylgalactosamine-containing oligosaccharide is the major complex-type structure present in Bowes melanoma tissue plasminogen activator. (1991 - Chan A, Morris H, Panico M, Etienne A, Rogers M, Gaffney P, Creighton-Kempsford L, Dell A) / Status : Reviewed Reported glycosite Tissue-type plasminogen activator / Homo sapiens Asn-219 Mass spectrometry observed peptide
Asn-219	N-Linked / Complex		Hex:4 HexNAc:5 dHex:1 NeuAc:2	taxonomy (1) protein (1) source (1) structure (1) composition (1) disease (1) reference (1) site (1) peptide (0) Taxonomy Homo sapiens (Human) Protein Tissue-type plasminogen activator / Homo sapiens P00750 Source Skin of Body (UBERON_0002097) HMCB (CVCL_3317) Reported structure N-Linked / Complex / NeuAc(a2-6)Gal(?1-?)GlcNAc(b1-2)Man(a1-?)[NeuAc(a2-6)GalNAc(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(?1-6)]GlcNAc Composition Hex:4 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2411.2187 ) Disease Melanoma (DOID:1909) Reference A novel sialylated N-acetylgalactosamine-containing oligosaccharide is the major complex-type structure present in Bowes melanoma tissue plasminogen activator. (1991 - Chan A, Morris H, Panico M, Etienne A, Rogers M, Gaffney P, Creighton-Kempsford L, Dell A) / Status : Reviewed Reported glycosite Tissue-type plasminogen activator / Homo sapiens Asn-219 Mass spectrometry observed peptide
Asn-219	N-Linked / Complex		Hex:3 HexNAc:6 dHex:1	taxonomy (1) protein (1) source (1) structure (1) composition (1) disease (1) reference (1) site (1) peptide (0) Taxonomy Homo sapiens (Human) Protein Tissue-type plasminogen activator / Homo sapiens P00750 Source Skin of Body (UBERON_0002097) HMCB (CVCL_3317) Reported structure N-Linked / Complex / GalNAc(b1-4)GlcNAc(b1-2)Man(a1-3)[GalNAc(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc Composition Hex:3 HexNAc:6 dHex:1 (avg mass : 1869.7555 ) Disease Melanoma (DOID:1909) Reference The glycosylation of Bowes melanoma tissue plasminogen activator: lectin mapping, reaction with anti-L2/HNK-1 antibodies and the presence of sulphated/glucuronic acid containing glycans. (1996 - Jaques A, Opdenakker G, Rademacher T, Dwek R, Zamze S) / Status : Reviewed Reported glycosite Tissue-type plasminogen activator / Homo sapiens Asn-219 Mass spectrometry observed peptide

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