Apolipoprotein C-III

Taxonomy

• Homo sapiens (Human)

Protein

• Apolipoprotein C-III / Homo sapiens    P02656

Source

• Blood Plasma (UBERON_0001969)  
• Cerebrospinal Fluid (UBERON_0001359)  
• Urine (UBERON_0001088)  
• Very-Low-Density Lipoprotein Particle (GO_0034361)  

Reported structure

• O-Linked / Core 1 / NeuAc(a2-3)Gal(b1-3)GalNAc
• O-Linked / Core 1 / Neu5Ac(?2-?)Gal(b1-3)[Neu5Ac(?2-?)]GalNAc(a1-
• O-Linked / Core 1 / NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc

Composition

• Hex:1 HexNAc:1 (avg mass : 383.3527 )
• Hex:1 HexNAc:1 NeuAc:1 (avg mass : 674.6106 )
• Hex:1 HexNAc:1 NeuAc:2 (avg mass : 965.8685 )

Disease

• Hyperlipoproteinemia, Familial Type V (DOID:1171)

Reference

• Glycomic analysis of high density lipoprotein shows a highly sialylated particle (2014 - Huang J1, Lee H, Zivkovic AM, Smilowitz JT, Rivera N, German JB, Lebrilla CB) / Status : Reviewed
• LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins (2013 - Halim A, Rüetschi U, Larson G, Nilsson J) / Status : Reviewed
• Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD (2012 - Halim A, Nilsson J, Rüetschi U, Hesse C, Larson G) / Status : Reviewed
• Enrichment of glycopeptides for glycan structure and attachment site identification (2009 - Nilsson J, Rüetschi U, Halim A, Hesse C, Carlsohn E, Brinkmalm G, Larson G.) / Status : Reviewed
• Characterization of the oligosaccharide side chain of apolipoprotein C-III from human plasma very low density lipoproteins. (1978 - Vaith P, Assmann G, Uhlenbruck G) / Status : Reviewed

Reported glycosite

• Apolipoprotein C-III / Homo sapiens
  •        Thr-94

Mass spectrometry observed peptide