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taxonomy (1) protein (1) source (2) structure (5) composition (6) disease (1) reference (4) site (4) peptide (2)

Taxonomy

Homo sapiens (Human)

Protein

Sex hormone-binding globulin / Homo sapiens P04278

Source

Blood Serum (UBERON_0001977)
Mammary Gland (UBERON_0001911)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)

Reference

Community Evaluation of Glycoproteomics Informatics Solutions Reveals High-Performance Search Strategies for Glycopeptide Analysis (2021 - Rebeca Kawahara, Kathirvel Alagesan, Marshall Bern, Meng Bo, Weiqian Cao, Robert J Chalkley, Kai Cheng, Matthew S. Choo, Nathan Edwards, Radoslav Goldman, Marcus Hoffmann, Yingwei Hu, Yifan Huang, Jin Young Kim, Doron Kletter, Benoit Liquet-Weiland, Mingqi Liu, Yehia Mechref, Sriram Neelamegham, Terry Nguyen-Khuong, Jonas Nilsson, Adam Pap, Gun Wook Park, Benjamin L. Parker, Cassandra L. Pegg, Josef M. Penninger, Toan K. Phung, Markus Pioch, Erdmann Rapp, Enes Sakalli, Miloslav Sanda, Benjamin L. Schulz, Nichollas Scott, Georgy Sofronov, Johannes Stadlmann, Sergey Vakhrushev, Christina Woo, Hung-Yi Wu, Pengyuan Yang, Wantao Ying, Zhang Yong, Hui Zhang, Jingfu Zhao, Joseph Zaia, Stuart M. Haslam, Giuseppe Palmisano, Jong Shin Yoo, Goran Larson, Kai-Hooi Khoo, Katalin F. Medzihradszky, Daniel Kolarich, Nicolle H. Packer, and Morten Thaysen-Andersen) / Status : Reviewed
Site-Specific Profiling of Serum Glycoproteins Using N-Linked Glycan and Glycosite Analysis Revealing Atypical N-Glycosylation Sites on Albumin and α-1B-Glycoprotein (2018 - Shisheng Sun, Yingwei Hu, Li Jia, Shadi Toghi Eshghi, Yang Liu, Punit Shah, Hui Zhang) / Status : Unreviewed
Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
Study of the carbohydrate moiety of human serum sex hormone-binding globulin. (1983 - Avvakumov G, Matveentseva I, Akhrem L, Strel'chyonok O, Akhrem A) / Status : Reviewed

Reported glycosite

Sex hormone-binding globulin / Homo sapiens
- Undefined site
- Thr-36
- Asn-380
- Asn-396

Mass spectrometry observed peptide

LDVDQALNR (9aa)
- P04278 Asn-380
SHEIWTHSCPQSPGNGTDASH (21aa)
- P04278 Asn-396

- N-Linked / Complex (avg mass : 2224.0231)
- N-Linked / Complex (avg mass : 2370.1661)
- O-Linked / Core 1 (avg mass : 674.6106)
- O-Linked / Core 1 (avg mass : 674.6106)
- O-Linked / Core 1 (avg mass : 965.8685)

- Hex:5 HexNAc:4 NeuAc:1 / N-Linked (avg mass : 1932.7652)
- Hex:5 HexNAc:4 NeuAc:2 / N-Linked (avg mass : 2224.0231)
- Hex:6 HexNAc:4 dHex:1 NeuAc:1 / N-Linked (avg mass : 2241.0506)