GlyConnect

taxonomy (1) protein (1) source (3) structure (7) composition (10) disease (2) reference (7) site (5) peptide (4)

Taxonomy

Homo sapiens (Human)

Protein

Plasminogen / Homo sapiens P00747

Source

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)
Prostate cancer (DOID:10283)

Reference

Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
Site-Specific Profiling of Serum Glycoproteins Using N-Linked Glycan and Glycosite Analysis Revealing Atypical N-Glycosylation Sites on Albumin and α-1B-Glycoprotein (2018 - Shisheng Sun, Yingwei Hu, Li Jia, Shadi Toghi Eshghi, Yang Liu, Punit Shah, Hui Zhang) / Status : Unreviewed
Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
Evidence for a novel O-linked sialylated trisaccharide on Ser-248 of human plasminogen 2. (1997 - Pirie-Shepherd S, Stevens R, Andon N, Enghild J, Pizzo S) / Status : Reviewed
Oligosaccharide processing in the expression of human plasminogen cDNA by lepidopteran insect (Spodoptera frugiperda) cells. (1990 - Davidson D, Fraser M, Castellino F) / Status : Reviewed
The N- and O-linked carbohydrate chains of human, bovine and porcine plasminogen. Species specificity in relation to sialylation and fucosylation patterns. (1988 - Marti T, Schaller J, Rickli E, Schmid K, Kamerling J, Gerwig G, van Halbeek H, Vliegenthart J) / Status : Reviewed
Carbohydrate of the human plasminogen variants. III. Structure of the O-glycosidically linked oligosaccharide unit. (1979 - Hayes M, Castellino F) / Status : Reviewed

Reported glycosite

Plasminogen / Homo sapiens
- Asn-150
- Ser-268
- Asn-308
- Thr-365
- Asn-415

Mass spectrometry observed peptide

FSPATHPSEGLEENYCR (17aa)
- P00747 Asn-150
GNVAVTVSGHTCQHWSAQTPHTHNR (25aa)
- P00747 Asn-308
SAQTPHTHNR (10aa)
- P00747 Asn-308
TPENYPNAGLTMNYCR (16aa)
- P00747 Asn-415

- O-Linked / Core 1 (avg mass : 674.6106)
- O-Linked / Core 1 (avg mass : 965.8685)
- N-Linked / Complex (avg mass : 1641.5073)
- N-Linked / Complex (avg mass : 1932.7652)
- N-Linked / Complex (avg mass : 2078.9082)
- N-Linked / Complex (avg mass : 2224.0231)
- N-Linked / Complex (avg mass : 2370.1661)

- Hex:5 HexNAc:4 / N-Linked (avg mass : 1641.5073)
- Hex:5 HexNAc:3 NeuAc:1 / N-Linked (avg mass : 1729.5702)
- Hex:5 HexNAc:4 NeuAc:1 / N-Linked (avg mass : 1932.7652)
- Hex:5 HexNAc:4 NeuAc:2 / N-Linked (avg mass : 2224.0231)
- Hex:6 HexNAc:5 NeuAc:2 / N-Linked (avg mass : 2589.3605)
- Hex:6 HexNAc:5 dHex:2 NeuAc:2 / N-Linked (avg mass : 2881.6465)