GlyConnect

Taxonomy (1) Protein (1) Source (2) Structure (44) Composition (42) Disease (1) Site (3) Peptide (2)

Taxonomy

Homo sapiens (Human)

Protein

Alpha-n-acetylgalactosaminidase / Homo sapiens P17050

Source

Mammary Gland (UBERON_0001911)
CHO-DG44 (CVCL_7180) Ovary (UBERON_0000992)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)

Reported glycosite

Alpha-n-acetylgalactosaminidase / Homo sapiens :
- Undefined site
- Asn-124
- Asn-177

Mass spectrometry validated peptide

LGIYADMGNFTCMGYPGTTLDK (22aa)
- P17050 Asn-124
MAAAINATGR (10aa)
- P17050 Asn-177

- N-Linked / Hybrid (avg mass : 1988.72 )
- N-Linked / Complex (avg mass : 1828.7029 )
- N-Linked / Hybrid (avg mass : 1600.4547 )
- N-Linked / Complex (avg mass : 2444.2456 )
- N-Linked / Hybrid (avg mass : 2279.9779 )
- N-Linked / High-Mannose (avg mass : 1315.0972 )
- N-Linked / Complex (avg mass : 1787.6503 )
- N-Linked / Complex (avg mass : 2152.9877 )
- N-Linked / Hybrid (avg mass : 2133.8349 )
- N-Linked / Complex (avg mass : 3026.7614 )
- N-Linked / High-Mannose (avg mass : 1719.3619 )
- N-Linked / Complex (avg mass : 3392.0988 )
- N-Linked / Complex (avg mass : 2006.8447 )
- N-Linked / High-Mannose (avg mass : 1477.2396 )
- N-Linked / Complex (avg mass : 2735.5035 )
- N-Linked / Hybrid (avg mass : 1908.7401 )
- N-Linked / Hybrid (avg mass : 1600.4547 )
- N-Linked / Complex (avg mass : 2210.0397 )
- N-Linked / Complex (avg mass : 3100.8409 )
- N-Linked / High-Mannose (avg mass : 1235.1173 )
- N-Linked / High-Mannose (avg mass : 1639.382 )
- N-Linked / High-Mannose (avg mass : 1397.2597 )
- N-Linked / Hybrid (avg mass : 1762.5971 )
- N-Linked / Complex (avg mass : 3026.7614 )
- N-Linked / Complex (avg mass : 2152.9877 )
- N-Linked / Complex (avg mass : 1932.7652 )
- N-Linked / Complex (avg mass : 2006.8447 )
- N-Linked / Hybrid (avg mass : 1842.577 )
- N-Linked / Complex (avg mass : 1567.4278 )
- N-Linked / Complex (avg mass : 2518.3251 )
- N-Linked / Complex (avg mass : 1641.5073 )
- N-Linked / High-Mannose (avg mass : 1235.1173 )
- N-Linked / Complex (avg mass : 2370.1661 )
- N-Linked / Pauci-Mannose (avg mass : 910.8325 )
- N-Linked / Complex (avg mass : 2031.8979 )
- N-Linked / Complex (avg mass : 1422.3129 )
- N-Linked / Pauci-Mannose (avg mass : 1056.9755 )
- N-Linked / High-Mannose (avg mass : 1559.4021 )
- N-Linked / Complex (avg mass : 1828.7029 )
- N-Linked / Complex (avg mass : 2444.2456 )
- N-Linked / Complex (avg mass : 2224.0231 )
- N-Linked / Complex (avg mass : 2735.5035 )
- N-Linked / Complex (avg mass : 2809.583 )
- N-Linked / Complex (avg mass : 2078.9082 )

- Hex:6 HexNAc:2 (avg mass : 1397.2597 )
- Hex:3 HexNAc:2 (avg mass : 910.8325 )
- Hex:5 HexNAc:3 NeuAc:1 (avg mass : 1729.5702 )
- Hex:5 HexNAc:3 dHex:2 (avg mass : 1730.5983 )
- Hex:5 HexNAc:2 dHex:1 (avg mass : 1381.2603 )
- Hex:7 HexNAc:2 (avg mass : 1559.4021 )
- Hex:6 HexNAc:3 (avg mass : 1600.4547 )
- Hex:5 HexNAc:2 (avg mass : 1235.1173 )
- Hex:3 HexNAc:2 dHex:1 (avg mass : 1056.9755 )
- Hex:6 HexNAc:3 dHex:2
- Hex:6 HexNAc:3 dHex:3
- Hex:4 HexNAc:2 dHex:1 (avg mass : 1219.1179 )
- Hex:4 HexNAc:3 NeuAc:1 (avg mass : 1567.4278 )

Protein and gene references

UniProtKB : P17050

neXtProt : NX_P17050

GeneCards : NAGA

3D structure from PDB

Select a PDB entry

Github Wiki

3D visualization by LiteMol

References (2)

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed

Human alpha-N-acetylgalactosaminidase: site occupancy and structure of N-linked oligosaccharides. (2000)
Ohta M, Ohnishi T, Ioannou Y, Hodgson M, Matsuura F, Desnick R
Pubmed : 10704524
Status : Reviewed