GlyConnect

taxonomy (1) protein (1) source (11) structure (5) composition (4) disease (1) reference (5) site (2) peptide (0)

Taxonomy

Homo sapiens (Human)

Protein

Non-secretory ribonuclease / Homo sapiens P10153

Source

Reported structure

Composition

Disease

Leukemia, Promyelocytic (DOID:0060318)

Reference

C-Mannosylation of human RNase 2 is an intracellular process performed by a variety of cultured cells. (1997 - Krieg J, Glasner W, Vicentini A, Doucey M, Loffler A, Hess D, Hofsteenge J) / Status : Reviewed
Spectroscopic and protein chemical analyses demonstrate the presence of C-mannosylated tryptophan in intact human RNase 2 and its isoforms. (1996 - Loffler A, Doucey M, Jansson A, Muller D, de Beer T, Hess D, Meldal M, Richter W, Vliegenthart J, Hofsteenge J) / Status : Reviewed
The hexopyranosyl residue that is C-glycosidically linked to the side chain of tryptophan-7 in human RNase Us is alpha-mannopyranose. (1995 - de Beer T, Vliegenthart J, Loffler A, Hofsteenge J) / Status : Reviewed
New type of linkage between a carbohydrate and a protein: C-glycosylation of a specific tryptophan residue in human RNase Us. (1994 - Hofsteenge J, Mller D, de Beer T, Lffler A, Richter W, Vliegenthart J) / Status : Reviewed
Human non-secretory ribonucleases. II. Structural characterization of the N-glycans of the kidney, liver and spleen enzymes by NMR spectroscopy and electrospray mass spectrometry. (1993 - Lawrence C, Little P, Little B, Glushka J, van Halbeek H, Alhadeff J) / Status : Reviewed

Reported glycosite

Non-secretory ribonuclease / Homo sapiens
- Undefined site
- Trp-34

Mass spectrometry observed peptide

- O-Linked/C-Linked / No-core (avg mass : 180.1577)
- C-Linked / Undefined core (avg mass : 180.1577)
- N-Linked / No-core (avg mass : 570.5483)
- N-Linked / No-core (avg mass : 894.8331)
- N-Linked / No-core (avg mass : 1098.0281)

- Hex:1 / C-Linked (avg mass : 180.1577)