Immunoglobulin alpha (non secretory)

Taxonomy

• Homo sapiens (Human)

Protein

• Immunoglobulin alpha (non secretory) / Homo sapiens    P01876    P01877

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Undefined core / Man(?1-3)Man(?1-3)Man(?1-3)Man(?1-?)GlcNAc(?1-?)GlcNAc(?1-?)GlcNAc
• O-Linked / Undefined core / NeuAc(a2-3)Gal(?1-6)GlcNAc(b1-?)GlcNAc(b1-?)Gal(b1-?)Gal(b1-?)GalNAc
• N-Linked / Undefined core / NeuAc(?2-?)Gal(b1-?)GlcNAc(?1-?)[NeuAc(?2-?)Gal(b1-?)GlcNAc(b1-?)Man(?1-?)]Man(?1-?)[GlcNAc(?1-?)]Man(?1-?)[Fuc(?1-?)]GlcNAc

Composition

• Hex:3 HexNAc:3 NeuAc:1 (avg mass : 1405.2854 )
• Hex:4 HexNAc:3 (avg mass : 1276.1699 )
• Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )

Disease

• Myeloma, Multiple (DOID:9538)

Reference

• Investigations on the oligosaccharide units of an A myeloma globulin. (1968 - Dawson G, Clamp JR) / Status : Reviewed

Reported glycosite

• Immunoglobulin alpha (non secretory) / Homo sapiens
  •        Undefined site

Mass spectrometry observed peptide