Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Blood Serum (UBERON_0001977)  

Reported structure

Composition

• Hex:6 HexNAc:5 dHex:1 NeuAc:3 (avg mass : 3026.7614 )

Disease

Reference

• Selective glycopeptide profiling by acetone enrichment and LC/MS (2014 - Takakura D, Harazono A, Hashii N, Kawasaki N) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site
  •        Asn-70
  •        Asn-107

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Blood Plasma (UBERON_0001969)  

Reported structure

Composition

• Hex:5 HexNAc:4 dHex:1 (avg mass : 1787.6503 )

Disease

• Esophageal cancer (DOID:5041)

Reference

• Glycomic analysis of high density lipoprotein shows a highly sialylated particle (2014 - Huang J1, Lee H, Zivkovic AM, Smilowitz JT, Rivera N, German JB, Lebrilla CB) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Blood Serum (UBERON_0001977)  

Reported structure

Composition

• Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )

Disease

Reference

• Selective glycopeptide profiling by acetone enrichment and LC/MS (2014 - Takakura D, Harazono A, Hashii N, Kawasaki N) / Status : Reviewed
• Simultaneous glycosylation analysis of human serum glycoproteins by high-performance liquid chromatography/tandem mass spectrometry (2008 - Harazono A, Kawasaki N, Itoh S, Hashii N, Matsuishi-Nakajima Y, Kawanishi T, Yamaguchi T) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Blood Serum (UBERON_0001977)  

Reported structure

Composition

• Hex:6 HexNAc:5 NeuAc:3 (avg mass : 2880.6184 )

Disease

Reference

• Selective glycopeptide profiling by acetone enrichment and LC/MS (2014 - Takakura D, Harazono A, Hashii N, Kawasaki N) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Blood Plasma (UBERON_0001969)  
• Blood Serum (UBERON_0001977)  

Reported structure

Composition

• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )

Disease

• Esophageal cancer (DOID:5041)

Reference

• Glycomic analysis of high density lipoprotein shows a highly sialylated particle (2014 - Huang J1, Lee H, Zivkovic AM, Smilowitz JT, Rivera N, German JB, Lebrilla CB) / Status : Reviewed
• Comparison of sialylated N-glycopeptide levels in serum of pancreatic cancer patients, acute pancreatitis patients, and healthy controls (2014 - Kontro H, Joenväärä S, Haglund C, Renkonen R) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Blood Serum (UBERON_0001977)  

Reported structure

Composition

• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )

Disease

Reference

• Selective glycopeptide profiling by acetone enrichment and LC/MS (2014 - Takakura D, Harazono A, Hashii N, Kawasaki N) / Status : Reviewed
• Simultaneous glycosylation analysis of human serum glycoproteins by high-performance liquid chromatography/tandem mass spectrometry (2008 - Harazono A, Kawasaki N, Itoh S, Hashii N, Matsuishi-Nakajima Y, Kawanishi T, Yamaguchi T) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site
  •        Asn-70

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )

Disease

Reference

• Studies on the oligosaccharide chains of human alpha 1-protease inhibitor. II. Structure of oligosaccharides. (1980 - Mega T, Lujan E, Yoshida A) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc

Composition

• Hex:5 HexNAc:4 dHex:1 (avg mass : 1787.6503 )

Disease

• Carcinoma, Hepatocellular (DOID:684)

Reference

• Structural analysis on the sugar chains of human alpha 1-antitrypsin: presence of fucosylated biantennary glycan in hepatocellular carcinoma. (1993 - Saitoh A, Aoyagi Y, Asakura H) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-4)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)]Man(a1-?)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• Hex:6 HexNAc:5 NeuAc:3 (avg mass : 2880.6184 )

Disease

Reference

• Studies on the oligosaccharide chains of human alpha 1-protease inhibitor. II. Structure of oligosaccharides. (1980 - Mega T, Lujan E, Yoshida A) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Blood Serum (UBERON_0001977)  

Reported structure

• N-Linked / Complex / Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• Hex:5 HexNAc:4 (avg mass : 1641.5073 )

Disease

• Carcinoma, Hepatocellular (DOID:684)

Reference

• Structural analysis on the sugar chains of human alpha 1-antitrypsin: presence of fucosylated biantennary glycan in hepatocellular carcinoma. (1993 - Saitoh A, Aoyagi Y, Asakura H) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Urine (UBERON_0001088)  

Reported structure

Composition

• Hex:5 HexNAc:4 (avg mass : 1641.5073 )

Disease

Reference

• Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD (2012 - Halim A, Nilsson J, Rüetschi U, Hesse C, Larson G) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Mammary Gland (UBERON_0001911)  

Reported structure

Composition

• Hex:6 HexNAc:5 dHex:1 NeuAc:3 (avg mass : 3026.7614 )

Disease

• Cancer, breast (DOID:1612)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site
  •        Asn-70
  •        Asn-107

Mass spectrometry validated peptide

• QLAHQSNSTNIFFSPVSIATAFAMLSLGTK (30aa)
  •    P01009    Asn-70

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Mammary Gland (UBERON_0001911)  

Reported structure

Composition

• Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )

Disease

• Cancer, breast (DOID:1612)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Asn-70

Mass spectrometry validated peptide

• QLAHQSNSTNIFFSPVSIATAFAMLSLGTK (30aa)
  •    P01009    Asn-70

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Blood Serum (UBERON_0001977)  
• Mammary Gland (UBERON_0001911)  

Reported structure

Composition

• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )

Disease

• Cancer, breast (DOID:1612)

Reference

• Site-Specific Profiling of Serum Glycoproteins Using N-Linked Glycan and Glycosite Analysis Revealing Atypical N-Glycosylation Sites on Albumin and α-1B-Glycoprotein (2018 - Shisheng Sun, Yingwei Hu, Li Jia, Shadi Toghi Eshghi, Yang Liu, Punit Shah, Hui Zhang) / Status : Unreviewed
• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site
  •        Asn-70

Mass spectrometry validated peptide

• QLAHQSNSTNIFFSPVSIATAF (22aa)
  •    P01009    Asn-70
• QLAHQSNSTNIFF (13aa)
  •    P01009    Asn-70
• QLAHQSNSTNIF (12aa)
  •    P01009    Asn-70
• QLAHQSNSTNIFFSPV (16aa)
  •    P01009    Asn-70
• QLAHQSNSTNIFFSPVSIATAFAMLSLGTK (30aa)
  •    P01009    Asn-70

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Mammary Gland (UBERON_0001911)  

Reported structure

Composition

• Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )

Disease

• Cancer, breast (DOID:1612)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Asn-70

Mass spectrometry validated peptide

• QLAHQSNSTNIFFSPVSIATAFAMLSLGTK (30aa)
  •    P01009    Asn-70

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Mammary Gland (UBERON_0001911)  

Reported structure

Composition

• Hex:12 HexNAc:2 (avg mass : 2370.1141 )

Disease

• Cancer, breast (DOID:1612)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Asn-70

Mass spectrometry validated peptide

• QLAHQSNSTNIFFSPVSIATAFAMLSLGTK (30aa)
  •    P01009    Asn-70

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Cerebrospinal Fluid Secretion (GO_0033326)  

Reported structure

• N-Linked / Complex / Structure 2011

Composition

• Hex:4 HexNAc:4 (avg mass : 1479.3649 )

Disease

Reference

• Enrichment of glycopeptides for glycan structure and attachment site identification (2009 - Nilsson J, Rüetschi U, Halim A, Hesse C, Carlsohn E, Brinkmalm G, Larson G.) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Asn-70

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Cerebrospinal Fluid Secretion (GO_0033326)  

Reported structure

• N-Linked / Complex / Structure 3041

Composition

• Hex:5 HexNAc:4 dHex:1 (avg mass : 1787.6503 )

Disease

Reference

• Enrichment of glycopeptides for glycan structure and attachment site identification (2009 - Nilsson J, Rüetschi U, Halim A, Hesse C, Carlsohn E, Brinkmalm G, Larson G.) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Asn-70

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Cerebrospinal Fluid Secretion (GO_0033326)  

Reported structure

• N-Linked / Complex / Gal(?1-?)GlcNAc(?1-?)Man(a1-3)[Gal(?1-?)GlcNAc(?1-?)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc

Composition

• Hex:5 HexNAc:4 (avg mass : 1641.5073 )

Disease

Reference

• Enrichment of glycopeptides for glycan structure and attachment site identification (2009 - Nilsson J, Rüetschi U, Halim A, Hesse C, Carlsohn E, Brinkmalm G, Larson G.) / Status : Reviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Asn-70

Mass spectrometry validated peptide

Taxonomy

• Homo sapiens (Human)

Protein

• Alpha-1-antitrypsin / Homo sapiens    P01009

Source

• Mammary Gland (UBERON_0001911)  

Reported structure

Composition

• Hex:6 HexNAc:5 dHex:1 NeuAc:3 (avg mass : 3026.7614 )

Disease

• Cancer, breast (DOID:1612)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed

Reported glycosite

• Alpha-1-antitrypsin / Homo sapiens :
  •        Undefined site
  •        Asn-70
  •        Asn-107

Mass spectrometry validated peptide

• ADTHDEIIEGINFNITEIPEAQIHEGFQEIIR (32aa)
  •    P01009    Asn-107