Neuropilin-1

Taxonomy

• Homo sapiens (Human)

Protein

• Neuropilin-1 / Homo sapiens    O14786

Source

• Blood Serum (UBERON_0001977)  
• Mammary Gland (UBERON_0001911)  

Reported structure

Composition

• Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )
• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )
• Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )
• Hex:6 HexNAc:5 dHex:1 NeuAc:3 (avg mass : 3026.7614 )
• Hex:7 HexNAc:6 dHex:1 NeuAc:3 (avg mass : 3392.0988 )
• Hex:12 HexNAc:2 (avg mass : 2370.1141 )

Disease

• Cancer, breast (DOID:1612)
• Prostate cancer (DOID:10283)

Reference

• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed
• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Site-Specific Profiling of Serum Glycoproteins Using N-Linked Glycan and Glycosite Analysis Revealing Atypical N-Glycosylation Sites on Albumin and α-1B-Glycoprotein (2018 - Shisheng Sun, Yingwei Hu, Li Jia, Shadi Toghi Eshghi, Yang Liu, Punit Shah, Hui Zhang) / Status : Unreviewed

Reported glycosite

• Neuropilin-1 / Homo sapiens
  •        Asn-150
  •        Asn-261
  •        Asn-522
  •        Asn-892

Mass spectrometry observed peptide

• GPECSQNYTTPSGVIK (16aa)
  •    O14786    Asn-150
• RGPECSQNYTTPSGVIK (17aa)
  •    O14786    Asn-150
• EGFSANYSVIQSSVSEDFK (19aa)
  •    O14786    Asn-261
• EGFSANYSVLQSSVSEDFK (19aa)
  •    O14786    Asn-261
• IGYSNNGSDWK (11aa)
  •    O14786    Asn-522
• NLSALENYNFELVDGVK (17aa)
  •    O14786    Asn-892