GlyConnect

Taxonomy (1) Protein (1) Source (1) Structure (0) Composition (14) Disease (1) Site (1) Peptide (1)

Taxonomy

Homo sapiens (Human)

Protein

Neurocan core protein / Homo sapiens O14594

Source

Mammary Gland (UBERON_0001911)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)

Reported glycosite

Neurocan core protein / Homo sapiens :
- Asn-122

Mass spectrometry validated peptide

ANATLLLGPLR (11aa)
- O14594 Asn-122

- Hex:7 HexNAc:2 (avg mass : 1559.4021 )
- Hex:4 HexNAc:6 (avg mass : 1885.7549 )
- Hex:5 HexNAc:2 (avg mass : 1235.1173 )
- Hex:6 HexNAc:4 NeuAc:1 (avg mass : 2094.9076 )
- Hex:3 HexNAc:6 (avg mass : 1723.6125 )
- Hex:4 HexNAc:2 dHex:1 (avg mass : 1219.1179 )
- Hex:5 HexNAc:2 dHex:1 (avg mass : 1381.2603 )
- Hex:5 HexNAc:6 (avg mass : 2047.8973 )
- Hex:6 HexNAc:2 (avg mass : 1397.2597 )
- Hex:6 HexNAc:3 dHex:1 (avg mass : 1746.5977 )
- Hex:6 HexNAc:3 NeuAc:1 (avg mass : 1891.7126 )
- Hex:6 HexNAc:3 (avg mass : 1600.4547 )
- Hex:6 HexNAc:3 dHex:2
- Hex:4 HexNAc:6 dHex:1 (avg mass : 2031.8979 )

Protein and gene references

UniProtKB : O14594

neXtProt : NX_O14594

GeneCards : NCAN

3D structure from PDB

Either no PDB or existing PDB of non-glycosylated form

References (1)

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed