GlyConnect

Taxonomy (1) Protein (1) Source (1) Structure (0) Composition (13) Disease (1) Site (1) Peptide (1)

Taxonomy

Homo sapiens (Human)

Protein

Nephronectin / Homo sapiens Q6UXI9

Source

Mammary Gland (UBERON_0001911)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)

Reported glycosite

Nephronectin / Homo sapiens :
- Asn-273

Mass spectrometry validated peptide

GNGTILK (7aa)
- Q6UXI9 Asn-273

- Hex:5 HexNAc:4 dHex:4
- Hex:4 HexNAc:5 NeuAc:1 (avg mass : 1973.8178 )
- Hex:5 HexNAc:5 dHex:1 (avg mass : 1990.8453 )
- Hex:3 HexNAc:6 dHex:1 NeuAc:1 (avg mass : 2161.0134 )
- Hex:5 HexNAc:5 dHex:3 (avg mass : 2283.1313 )
- Hex:12 HexNAc:2 (avg mass : 2370.1141 )
- Hex:5 HexNAc:4 dHex:2 NeuAc:1 (avg mass : 2225.0512 )
- Hex:4 HexNAc:6 dHex:2 (avg mass : 2178.0409 )
- Hex:4 HexNAc:5 dHex:3 (avg mass : 2120.9889 )
- Hex:6 HexNAc:4 dHex:3 (avg mass : 2242.0787 )
- Hex:5 HexNAc:4 dHex:3 (avg mass : 2079.9363 )
- Hex:4 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2119.9608 )
- Hex:4 HexNAc:5 dHex:2 NeuAc:1 (avg mass : 2266.1038 )

Protein and gene references

UniProtKB : Q6UXI9

neXtProt : NX_Q6UXI9

GeneCards : NPNT

GlycoDomain : Q6UXI9

3D structure from PDB

Either no PDB or existing PDB of non-glycosylated form

References (1)

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed