Neogenin

Taxonomy

• Homo sapiens (Human)

Protein

• Neogenin / Homo sapiens    Q92859

Source

• Blood Serum (UBERON_0001977)  
• Mammary Gland (UBERON_0001911)  

Reported structure

Composition

• Hex:4 HexNAc:3 dHex:1 NeuAc:1 (avg mass : 1713.5708 )
• Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )
• Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )
• Hex:6 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2241.0506 )
• Hex:6 HexNAc:5 NeuAc:1 (avg mass : 2298.1026 )
• Hex:6 HexNAc:5 NeuAc:2 (avg mass : 2589.3605 )
• Hex:6 HexNAc:5 dHex:1 NeuAc:3 (avg mass : 3026.7614 )
• Hex:6 HexNAc:6 NeuAc:2 (avg mass : 2792.5555 )
• Hex:6 HexNAc:6 dHex:1 NeuAc:2 (avg mass : 2938.6985 )
• Hex:12 HexNAc:2 (avg mass : 2370.1141 )

Disease

• Cancer, breast (DOID:1612)
• Prostate cancer (DOID:10283)

Reference

• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed
• Large-scale intact glycopeptide identification by Mascot database search (2018 - Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede) / Status : Unreviewed

Reported glycosite

• Neogenin / Homo sapiens
  •        Asn-210
  •        Asn-470
  •        Asn-639
  •        Asn-1146
  •        Asn-1298

Mass spectrometry observed peptide

• LPSGMLVISNATEGDGGLYR (20aa)
  •    Q92859    Asn-210     Neogenin / Homo sapiens
• TPASDPHGDNITYSVFYTK (19aa)
  •    Q92859    Asn-470     Neogenin / Homo sapiens
• TPASDPHGDNLTYSVFYTK (19aa)
  •    Q92859    Asn-470     Neogenin / Homo sapiens
• TLSDVPSAAPQNLSLEVR (18aa)
  •    Q92859    Asn-639     Neogenin / Homo sapiens
• TISDVPSAAPQNISIEVR (18aa)
  •    Q92859    Asn-639     Neogenin / Homo sapiens
• SVNGSHK (7aa)
  •    Q92859    Asn-1146     Neogenin / Homo sapiens
• ANSTESVR (8aa)
  •    Q92859    Asn-1298     Neogenin / Homo sapiens