GlyConnect

Taxonomy (1) Protein (1) Source (1) Structure (0) Composition (10) Disease (1) Site (2) Peptide (2)

Taxonomy

Homo sapiens (Human)

Protein

Leucyl-cystinyl aminopeptidase / Homo sapiens Q9UIQ6

Source

Mammary Gland (UBERON_0001911)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)

Reported glycosite

Leucyl-cystinyl aminopeptidase / Homo sapiens :
- Asn-834
- Asn-850

Mass spectrometry validated peptide

SAIIEFACTHNIGNCSTTAMK (21aa)
- Q9UIQ6 Asn-834
IFDDWMASNGTQSIPTDVMTTVFK (24aa)
- Q9UIQ6 Asn-850

- Hex:6 HexNAc:5 NeuAc:3 (avg mass : 2880.6184 )
- Hex:6 HexNAc:5 dHex:3 NeuAc:1
- Hex:6 HexNAc:5 dHex:4 (avg mass : 2591.4167 )
- Hex:6 HexNAc:5 dHex:2 NeuAc:1 (avg mass : 2590.3886 )
- Hex:6 HexNAc:5 dHex:1 NeuAc:3 (avg mass : 3026.7614 )
- Hex:6 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2735.5035 )
- Hex:7 HexNAc:6 (avg mass : 2372.1821 )
- Hex:6 HexNAc:5 dHex:3 (avg mass : 2445.2737 )
- Hex:8 HexNAc:7 (avg mass : 2737.5195 )
- Hex:6 HexNAc:5 NeuAc:2 (avg mass : 2589.3605 )

Protein and gene references

UniProtKB : Q9UIQ6

neXtProt : NX_Q9UIQ6

GeneCards : LNPEP

GlycoDomain : Q9UIQ6

3D structure from PDB

Select a PDB entry

Github Wiki

3D visualization by LiteMol

References (1)

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed