GlyConnect

Taxonomy (1) Protein (1) Source (2) Structure (0) Composition (11) Disease (1) Site (2) Peptide (2)

Taxonomy

Homo sapiens (Human)

Protein

Ig gamma-3 chain C region / Homo sapiens P01860

Source

Blood Serum (UBERON_0001977)
Mammary Gland (UBERON_0001911)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)

Reported glycosite

Ig gamma-3 chain C region / Homo sapiens :
- Asn-227
- Asn-322

Mass spectrometry validated peptide

EEQYNSTFR (9aa)
- P01860 Asn-227
GFYPSDIAVEWESSGQPENNYNTTPPMLDSDGSFFLYSK (39aa)
- P01860 Asn-322

- Hex:5 HexNAc:4 dHex:1 (avg mass : 1787.6503 )
- Hex:3 HexNAc:4 dHex:1 (avg mass : 1463.3655 )
- Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )
- Hex:4 HexNAc:5 dHex:1 (avg mass : 1828.7029 )
- Hex:5 HexNAc:4 (avg mass : 1641.5073 )
- Hex:4 HexNAc:5 (avg mass : 1682.5599 )
- Hex:3 HexNAc:5 dHex:1 (avg mass : 1666.5605 )
- Hex:4 HexNAc:4 (avg mass : 1479.3649 )
- Hex:5 HexNAc:5 (avg mass : 1844.7023 )
- Hex:3 HexNAc:5 (avg mass : 1520.4175 )
- Hex:4 HexNAc:4 dHex:1 (avg mass : 1625.5079 )

Protein and gene references

UniProtKB : P01860

neXtProt : NX_P01860

GeneCards : IGHG3

3D structure from PDB

Select a PDB entry

Github Wiki

3D visualization by LiteMol

References (2)

Site-Specific Profiling of Serum Glycoproteins Using N-Linked Glycan and Glycosite Analysis Revealing Atypical N-Glycosylation Sites on Albumin and α-1B-Glycoprotein (2018)
Shisheng Sun, Yingwei Hu, Li Jia, Shadi Toghi Eshghi, Yang Liu, Punit Shah, Hui Zhang
Pubmed : 29671580 DOI : 10.1021/acs.analchem.8b01051
Status : Unreviewed

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed