GlyConnect

Taxonomy (1) Protein (1) Source (1) Structure (0) Composition (11) Disease (1) Site (1) Peptide (1)

Taxonomy

Homo sapiens (Human)

Protein

HLA class II histocompatibility antigen, DRB1-10 beta chain / Homo sapiens Q30167

Source

Mammary Gland (UBERON_0001911)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)

Reported glycosite

HLA class II histocompatibility antigen, DRB1-10 beta chain / Homo sapiens :
- Asn-48

Mass spectrometry validated peptide

FECHFFNGTER (11aa)
- Q30167 Asn-48

- Hex:12 HexNAc:2 (avg mass : 2370.1141 )
- Hex:8 HexNAc:2 (avg mass : 1721.5445 )
- Hex:3 HexNAc:2 dHex:1 (avg mass : 1056.9755 )
- Hex:8 HexNAc:7 NeuAc:1
- Hex:6 HexNAc:5 dHex:3 NeuAc:1
- Hex:6 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2735.5035 )
- Hex:6 HexNAc:2 (avg mass : 1397.2597 )
- Hex:5 HexNAc:6 (avg mass : 2047.8973 )
- Hex:4 HexNAc:3 dHex:1 NeuAc:1 (avg mass : 1713.5708 )
- Hex:6 HexNAc:5 dHex:1 NeuAc:3 (avg mass : 3026.7614 )
- Hex:9 HexNAc:2 (avg mass : 1883.6869 )

Protein and gene references

UniProtKB : Q30167

neXtProt : NX_Q30167

GeneCards : HLA-DRB1

3D structure from PDB

Either no PDB or existing PDB of non-glycosylated form

References (1)

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed