GlyConnect

Taxonomy (1) Protein (1) Source (1) Structure (0) Composition (13) Disease (1) Site (5) Peptide (9)

Taxonomy

Homo sapiens (Human)

Protein

Endoplasmin / Homo sapiens P14625

Source

Mammary Gland (UBERON_0001911)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)

Reported glycosite

Endoplasmin / Homo sapiens :
- Asn-62
- Asn-107
- Asn-217
- Asn-445
- Asn-502

Mass spectrometry validated peptide

ELISNASDALDK (12aa)
- P14625 Asn-107
TDDEVVQREEEAIQIDGINASQIR (24aa)
- P14625 Asn-62
EGSRTDDEVVQREEEAIQLDGLNASQIR (28aa)
- P14625 Asn-62
EEEAIQLDGLNASQIR (16aa)
- P14625 Asn-62
HNNDTQHIWESDSNEFSVIADPR (23aa)
- P14625 Asn-217
HNNDTQHIWE (10aa)
- P14625 Asn-217
HNNDTQHIWESDSNE (15aa)
- P14625 Asn-217
GVVDSDDIPINVSR (14aa)
- P14625 Asn-445
IGVIEDHSNR (10aa)
- P14625 Asn-502

- Hex:7 HexNAc:2 (avg mass : 1559.4021 )
- Hex:4 HexNAc:3 (avg mass : 1276.1699 )
- Hex:5 HexNAc:2 dHex:1 (avg mass : 1381.2603 )
- Hex:3 HexNAc:2 dHex:1 (avg mass : 1056.9755 )
- Hex:8 HexNAc:2 (avg mass : 1721.5445 )
- Hex:6 HexNAc:2 (avg mass : 1397.2597 )
- Hex:3 HexNAc:6 (avg mass : 1723.6125 )
- Hex:4 HexNAc:2 dHex:1 (avg mass : 1219.1179 )
- Hex:3 HexNAc:3 dHex:2 (avg mass : 1406.3135 )
- Hex:5 HexNAc:2 (avg mass : 1235.1173 )
- Hex:3 HexNAc:4 dHex:1 (avg mass : 1463.3655 )
- Hex:3 HexNAc:3 dHex:1 (avg mass : 1260.1705 )
- Hex:9 HexNAc:2 (avg mass : 1883.6869 )

Protein and gene references

UniProtKB : P14625

neXtProt : NX_P14625

GeneCards : HSP90B1

GlycoDomain : P14625

3D structure from PDB

Either no PDB or existing PDB of non-glycosylated form

References (1)

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed