E3 ubiquitin-protein ligase HERC2

Taxonomy

• Homo sapiens (Human)

Protein

• E3 ubiquitin-protein ligase HERC2 / Homo sapiens    O95714

Source

• Blood Serum (UBERON_0001977)  
• Mammary Gland (UBERON_0001911)  

Reported structure

Composition

• Hex:5 HexNAc:4 NeuAc:1 (avg mass : 1932.7652 )
• Hex:6 HexNAc:2 (avg mass : 1397.2597 )

Disease

• Cancer, breast (DOID:1612)

Reference

• Site-Specific Profiling of Serum Glycoproteins Using N-Linked Glycan and Glycosite Analysis Revealing Atypical N-Glycosylation Sites on Albumin and α-1B-Glycoprotein (2018 - Shisheng Sun, Yingwei Hu, Li Jia, Shadi Toghi Eshghi, Yang Liu, Punit Shah, Hui Zhang) / Status : Unreviewed
• Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018 - Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang) / Status : Unreviewed

Reported glycosite

• E3 ubiquitin-protein ligase HERC2 / Homo sapiens
  •        Asn-2790
  •        Asn-3746

Mass spectrometry observed peptide

• SLNVSSSVNQASR (13aa)
  •    O95714    Asn-2790
• LNLASNR (7aa)
  •    O95714    Asn-3746