GlyConnect

taxonomy (1) protein (1) source (1) structure (16) composition (15) disease (0) reference (2) site (2) peptide (0)

Taxonomy

Bos taurus (Bovine)

Protein

Corticotropin - lipotropin, npp peptide / Bos taurus P01190

Source

Neurohypophysis (UBERON_0002198)

Reported structure

Composition

Disease

Reference

O-glycosylation mimics N-glycosylation in the 16-KDa fragment of bovine pro-opiomelanocortin. The major O-glycan attached to Thr-45 carries SO4-4GalNAc beta 1-4GlcNAc beta 1-, which is the archetypal non-reducing epitope in the N-glycans of pituitary glycohormones. (1994 - Siciliano R, Morris H, Bennett H, Dell A) / Status : Reviewed
The Lewis x epitope is a major non-reducing structure in the sulphated N-glycans attached to Asn-65 of bovine pro-opiomelanocortin. (1993 - Siciliano R, Morris H, McDowell R, Azadi P, Rogers M, Bennett H, Dell A) / Status : Reviewed

Reported glycosite

Corticotropin - lipotropin, npp peptide / Bos taurus
- Thr-71
- Asn-91

Mass spectrometry observed peptide

- O-Linked / Core 1 (avg mass : 383.3527)
- O-Linked / Core 2 (avg mass : 748.6901)
- O-Linked / Core 2 (avg mass : 869.8069)
- O-Linked / Undefined core (avg mass : 935.8857)
- N-Linked / Complex (avg mass : 1463.3655)
- N-Linked / Complex (avg mass : 1543.4297)
- N-Linked / Complex (avg mass : 1625.5079)
- N-Linked / Complex (avg mass : 1666.5605)
- N-Linked / Complex (avg mass : 1746.6247)
- N-Linked / Complex (avg mass : 1787.6503)
- N-Linked / Complex (avg mass : 1828.7029)
- N-Linked / Complex (avg mass : 1908.7671)
- N-Linked / Complex (avg mass : 1933.7933)
- N-Linked / Complex (avg mass : 1974.8459)
- N-Linked / Complex (avg mass : 1974.8459)
- N-Linked / Complex (avg mass : 2054.9101)