GlyConnect

Taxonomy (1) Protein (1) Source (2) Structure (0) Composition (12) Disease (2) Site (4) Peptide (4)

Taxonomy

Homo sapiens (Human)

Protein

Cholinesterase / Homo sapiens P06276

Source

Blood Serum (UBERON_0001977)
Mammary Gland (UBERON_0001911)

Reported structure

Composition

Disease

Prostate cancer (DOID:10283)
Cancer, breast (DOID:1612)

Reported glycosite

Cholinesterase / Homo sapiens :
- Asn-85
- Asn-284
- Asn-369
- Asn-509

Mass spectrometry validated peptide

WSDIWNATK (9aa)
- P06276 Asn-85
ENETEIIK (8aa)
- P06276 Asn-284
DNNSIITR (8aa)
- P06276 Asn-369
YGNPNETQNNSTSWPVFK (18aa)
- P06276 Asn-509

- Hex:5 HexNAc:4 NeuAc:2 (avg mass : 2224.0231 )
- Hex:6 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2444.2456 )
- Hex:6 HexNAc:5 dHex:2 NeuAc:1 (avg mass : 2590.3886 )
- Hex:6 HexNAc:6 NeuAc:2 (avg mass : 2792.5555 )
- Hex:6 HexNAc:6 dHex:1 NeuAc:3 (avg mass : 3229.9564 )
- Hex:5 HexNAc:4 dHex:1 NeuAc:1 (avg mass : 2078.9082 )
- Hex:6 HexNAc:5 dHex:1 NeuAc:3 (avg mass : 3026.7614 )
- Hex:6 HexNAc:5 dHex:2 NeuAc:3
- Hex:5 HexNAc:4 dHex:1 NeuAc:2 (avg mass : 2370.1661 )
- Hex:6 HexNAc:5 dHex:1 NeuAc:2 (avg mass : 2735.5035 )
- Hex:6 HexNAc:6 NeuAc:3 (avg mass : 3083.8134 )
- Hex:6 HexNAc:6 dHex:3 NeuAc:2

Protein and gene references

UniProtKB : P06276

neXtProt : NX_P06276

GeneCards : BCHE

3D structure from PDB

Select a PDB entry

Github Wiki

3D visualization by LiteMol

References (2)

Large-scale intact glycopeptide identification by Mascot database search (2018)
Ravi Chand Bollineni, Christian Jeffrey Koehler, Randi Elin Gislefoss, Jan Haug Anonsen, Bernd Thiede
Pubmed : 29391424 DOI : 10.1038/s41598-018-20331-2
Status : Unreviewed

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed