GlyConnect

Taxonomy (1) Protein (1) Source (1) Structure (0) Composition (16) Disease (1) Site (3) Peptide (5)

Taxonomy

Homo sapiens (Human)

Protein

CD63 antigen / Homo sapiens P08962

Source

Mammary Gland (UBERON_0001911)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)

Reported glycosite

CD63 antigen / Homo sapiens :
- Asn-130
- Asn-150
- Asn-172

Mass spectrometry validated peptide

NNHTASIIDR (10aa)
- P08962 Asn-130
CCGAANYTDWEK (12aa)
- P08962 Asn-150
GAANYTDWEK (10aa)
- P08962 Asn-150
NRVPDSCCINVTVGCGINFNEK (22aa)
- P08962 Asn-172
VPDSCCINVTVGCGINFNEK (20aa)
- P08962 Asn-172

- Hex:8 HexNAc:2 (avg mass : 1721.5445 )
- Hex:3 HexNAc:2 dHex:1 (avg mass : 1056.9755 )
- Hex:4 HexNAc:6 dHex:2 (avg mass : 2178.0409 )
- Hex:7 HexNAc:6 dHex:4
- Hex:5 HexNAc:4 dHex:4
- Hex:6 HexNAc:3 dHex:2
- Hex:6 HexNAc:3 dHex:1 NeuAc:1 (avg mass : 2037.8556 )
- Hex:6 HexNAc:5 dHex:3 (avg mass : 2445.2737 )
- Hex:4 HexNAc:6 dHex:1 (avg mass : 2031.8979 )
- Hex:6 HexNAc:3 NeuAc:1 (avg mass : 1891.7126 )
- Hex:4 HexNAc:3 dHex:1 NeuAc:1 (avg mass : 1713.5708 )
- Hex:4 HexNAc:3 dHex:3
- Hex:5 HexNAc:4 dHex:3 (avg mass : 2079.9363 )
- Hex:5 HexNAc:3 dHex:3
- Hex:3 HexNAc:3 dHex:1 (avg mass : 1260.1705 )
- Hex:6 HexNAc:3 dHex:3

Protein and gene references

UniProtKB : P08962

neXtProt : NX_P08962

GeneCards : CD63

3D structure from PDB

Either no PDB or existing PDB of non-glycosylated form

References (1)

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed