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  • GlyConnect >
  • GlycoProteins >
  • Cathepsin F

Cathepsin F

Taxonomy : Homo sapiens

SNFG, Text, Oxford
Taxonomy (1) Protein (1) Source (1) Structure (0) Composition (4) Disease (1) Site (2) Peptide (2)

    Taxonomy

  • Homo sapiens (Human)

    Protein

  • Cathepsin F / Homo sapiens    Q9UBX1

    Source

  • Mammary Gland (UBERON_0001911)  

    Reported structure

    Composition

  • Hex:5 HexNAc:4 dHex:2 NeuAc:1 (avg mass : 2225.0512 )
  • Hex:12 HexNAc:2 (avg mass : 2370.1141 )
  • Hex:6 HexNAc:2 (avg mass : 1397.2597 )
  • Hex:4 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2119.9608 )

    Disease

  • Cancer, breast (DOID:1612)

    Reported glycosite

  • Cathepsin F / Homo sapiens :
    •        Asn-195
    •        Asn-378

    Mass spectrometry validated peptide

  • NFVITYNR (8aa)
    •    Q9UBX1    Asn-195
  • VYINDSVEISQNEQK (15aa)
    •    Q9UBX1    Asn-378
  • 6 x 2 x
    • Hex:6 HexNAc:2 (avg mass : 1397.2597 )
    • Site (1) Suggested Structure (0)

        Suggested structure

        Reported glycosite

      • Cathepsin F / Homo sapiens :
        •        Asn-378
  • 4 x 5 x 1 x 1 x
    • Hex:4 HexNAc:5 dHex:1 NeuAc:1 (avg mass : 2119.9608 )
    • Site (1) Suggested Structure (0)

        Suggested structure

        Reported glycosite

      • Cathepsin F / Homo sapiens :
        •        Asn-195
  • 5 x 4 x 2 x 1 x
    • Hex:5 HexNAc:4 dHex:2 NeuAc:1 (avg mass : 2225.0512 )
    • Site (1) Suggested Structure (0)

        Suggested structure

        Reported glycosite

      • Cathepsin F / Homo sapiens :
        •        Asn-195
  • 12 x 2 x
    • Hex:12 HexNAc:2 (avg mass : 2370.1141 )
    • Site (1) Suggested Structure (0)

        Suggested structure

        Reported glycosite

      • Cathepsin F / Homo sapiens :
        •        Asn-195

Protein and gene references

UniProtKB : Q9UBX1

neXtProt : NX_Q9UBX1

GeneCards : CTSF

3D structure from PDB

Either no PDB or existing PDB of non-glycosylated form

References (1)

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879   DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed

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