Cobra venom factor

Taxonomy

• Naja kaouthia (Monocled cobra)

Protein

• Cobra venom factor / Naja kaouthia    Q91132

Source

• Venom (UBERON_0007113)  

Reported structure

• N-Linked / Complex / {Fuc(a1-3)}k[Gal(b1-4)]GlcNAc(b1-2)Man(a1-3)[{Fuc(a1-3)}j[Gal(b1-4)]GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"where j+k=1.3"
• N-Linked / Complex / {Fuc(a1-3)}j[Gal(a1-3)Gal(b1-4)]GlcNAc(b1-2)Man(a1-?)[{Fuc(a1-3)}k[Gal(b1-4)]GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"where j+k=1.8"
• N-Linked / Complex / {Fuc(a1-3)}k[Gal(b1-4)]GlcNAc(b1-2)Man(a1-?)[{Fuc(a1-3)}j[NeuAc(a2-3)Gal(b1-4)]GlcNAc(b1-2)Man(a1-?)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"where j+k=1.2"
• N-Linked / Complex / Fuc(a1-3)[Gal(a1-3)Gal(b1-4)]GlcNAc(b1-2)Man(a1-3)[Fuc(a1-3)[Gal(a1-3)Gal(b1-4)]GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Man(a1-3)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Man(a1-6)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / {Fuc(a1-3)}j[NeuAc(a2-3)Gal(b1-4)]GlcNAc(b1-2)Man(a1-3)[{Fuc(a1-3)}k[NeuAc(a2-3)Gal(b1-4)]GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"where j+k=1.2"
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-4)]Man(a1-3)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ Gal(a1-3)"
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Man(a1-6)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ Gal(a1-3)"
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-4)]Man(a1-3)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ 2 x Gal(a1-3)"
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Man(a1-6)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ 2 x Gal(a1-3)"
• N-Linked / Complex / Fuc(a1-3)[Gal(a1-3)Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(a1-3)Gal(b1-4)]GlcNAc(b1-4)]Man(a1-3)[Fuc(a1-3)[Gal(a1-3)Gal(b1-4)]GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Fuc(a1-3)[Gal(a1-3)Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(a1-3)Gal(b1-4)]GlcNAc(b1-6)]Man(a1-6)[Fuc(a1-3)[Gal(a1-3)Gal(b1-4)]GlcNAc(b1-2)Man(a1-3)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-4)]Man(a1-3)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-4)]Man(a1-3)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ Gal(a1-3)"
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-4)]Man(a1-3)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ 2 x Gal(a1-3)"
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-4)]Man(a1-3)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ 3 x Gal(a1-3)"
• N-Linked / Complex / Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-4)]Man(a1-3)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-2)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc+"+ 4 x Gal(a1-3)"
• N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ 2 x Man"
• N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ 3 x Man"
• N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ 4 x Man"
• N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ 5 x Man"
• N-Linked / High-Mannose / Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc+"+ 6 x Man"

Composition

• Hex:5 HexNAc:2 (avg mass : 1235.1173 )
• Hex:5 HexNAc:4 dHex:3 (avg mass : 2079.9363 )
• Hex:5 HexNAc:4 dHex:3 NeuAc:1 (avg mass : 2371.1942 )
• Hex:5 HexNAc:4 dHex:3 NeuAc:2 (avg mass : 2662.4521 )
• Hex:6 HexNAc:2 (avg mass : 1397.2597 )
• Hex:6 HexNAc:4 dHex:3 (avg mass : 2242.0787 )
• Hex:6 HexNAc:5 dHex:4 (avg mass : 2591.4167 )
• Hex:7 HexNAc:2 (avg mass : 1559.4021 )
• Hex:7 HexNAc:4 dHex:3 (avg mass : 2404.2211 )
• Hex:7 HexNAc:5 dHex:4 (avg mass : 2753.5591 )
• Hex:7 HexNAc:6 dHex:5 (avg mass : 3102.8971 )
• Hex:8 HexNAc:2 (avg mass : 1721.5445 )
• Hex:8 HexNAc:5 dHex:4 (avg mass : 2915.7015 )
• Hex:8 HexNAc:6 dHex:5 (avg mass : 3265.0395 )
• Hex:9 HexNAc:2 (avg mass : 1883.6869 )
• Hex:9 HexNAc:5 dHex:4 (avg mass : 3077.8439 )
• Hex:9 HexNAc:6 dHex:5 (avg mass : 3427.1819 )
• Hex:10 HexNAc:6 dHex:5 (avg mass : 3589.3243 )
• Hex:11 HexNAc:6 dHex:5 (avg mass : 3751.4667 )

Disease

Reference

• N-linked oligosaccharides of cobra venom factor contain novel alpha(1-3)galactosylated Le(x) structures. (2001 - Gowda DC, Glushka J, van-Halbeek H , Thotakura RN, Bredehorst R, Vogel C-W) / Status : Reviewed

Reported glycosite

• Cobra venom factor / Naja kaouthia
  •        Undefined site

Mass spectrometry observed peptide