GlyConnect

Taxonomy (1) Protein (1) Source (1) Structure (0) Composition (13) Disease (1) Site (1) Peptide (2)

Taxonomy

Homo sapiens (Human)

Protein

Aspartyl/asparaginyl beta-hydroxylase / Homo sapiens Q12797

Source

Mammary Gland (UBERON_0001911)

Reported structure

Composition

Disease

Cancer, breast (DOID:1612)

Reported glycosite

Aspartyl/asparaginyl beta-hydroxylase / Homo sapiens :
- Asn-452

Mass spectrometry validated peptide

IVQIFPNDTSIK (12aa)
- Q12797 Asn-452
QLFPNDTSLK (10aa)
- Q12797 Asn-452

- Hex:4 HexNAc:6 dHex:1 (avg mass : 2031.8979 )
- Hex:9 HexNAc:2 (avg mass : 1883.6869 )
- Hex:8 HexNAc:2 (avg mass : 1721.5445 )
- Hex:5 HexNAc:2 dHex:1 (avg mass : 1381.2603 )
- Hex:7 HexNAc:2 (avg mass : 1559.4021 )
- Hex:5 HexNAc:6 dHex:1 NeuAc:1 (avg mass : 2485.2982 )
- Hex:3 HexNAc:3 dHex:1 (avg mass : 1260.1705 )
- Hex:3 HexNAc:2 dHex:1 (avg mass : 1056.9755 )
- Hex:3 HexNAc:4 dHex:1 (avg mass : 1463.3655 )
- Hex:5 HexNAc:2 (avg mass : 1235.1173 )
- Hex:3 HexNAc:4 NeuAc:2 (avg mass : 1899.7383 )
- Hex:6 HexNAc:2 (avg mass : 1397.2597 )
- Hex:4 HexNAc:3 dHex:3

Protein and gene references

UniProtKB : Q12797

neXtProt : NX_Q12797

GeneCards : ASPH

3D structure from PDB

Either no PDB or existing PDB of non-glycosylated form

References (1)

Reanalysis of global proteomic and phosphoproteomic data identified a large number of glycopeptides (2018)
Yingwei Hu, Punit Shah, David J. Clark, Minghui Ao, Hui Zhang
Pubmed : 29741879 DOI : 10.1021/acs.analchem.8b01137
Status : Unreviewed